(n.) A disease characterized by thickening and fatty degeneration of the inner coat of the arteries.
Example Sentences:
(1) An atheroma is often associated with saccular aneurysms, but its effect on this pathological process is still unknown.
(2) The usefulness of the serotonin (5-HT2) antagonist ketanserin in the treatment of hypertension is evaluated with respect to its known antihypertensive property as well as in relation to its effect on hypertension-induced cardiovascular changes, platelet hyperreactivity, and atheroma formation.
(3) Intracoronary imaging after balloon angioplasty reveals that a significant amount of atheroma is still present, which may partly explain why the incidence of restenosis is high after percutaneous transluminal coronary angioplasty.
(4) Two young women with homozygous familial hypercholesterolaemia and coronary and aortic atheroma were treated by repeated plasma exchange, using a continuous-flow blood-cell separator, for 4 and 8 months.
(5) The specific labelling of atheroma involves mainly protoporphyrin, hematoporphyrin and also minor components of Photofrin II which are accumulated.
(6) Between 1984 and 1989, 29 iliac renal artery bypasses were performed in 29 patients (mean age 67.8 years) with severe renovascular disease due to atheroma.
(7) The atherosclerotic plaques in the venous grafts resembled those in the coronary arteries, the main difference being the occurrence of multiple atheromas (up to 4 in a single section), the high number of T lymphocytes and macrophages related to these sites and the presence of atheromas bordering directly onto the luminal surface.
(8) He subsequently suffered from mesenteric angina due to stenosis of the origin of the superior mesenteric artery and intermittent claudication due to aorto-iliac atheroma.
(9) These results, when taken together with previous data demonstrating that PB increases serum triglyceride in the rabbit but lowers it in the rat, suggest that the drug may be atherogenic in the rabbit but not in the rat which, in any case, is highly resistant to atheroma.
(10) The nature of graft occlusion is related to immediate failure, usually technical, early failure due to myo-intimal hyperplasia and late failure due to progression of atheroma.
(11) 36 patients had no detectable atheroma, 23 mild, 21 moderate, and 36 severe.
(12) The results showed that the bare tip produced the most effective ablation in arterial atheroma, followed by the metal probe and the spectraprobe.
(13) In the remaining 16 patients, who had severe atheroma, PTA was made necessary by ischaemic renal failure.
(14) By comparing these findings with those observed in three other cases, in which biopsy of the pulp of the toe was also performed, the hypothesis can be advanced that these juvenile encephalic ischemic accidents are caused by atheroma, which can be detected, at an early stage, by studying the distal arteries in the finger or toe pulp.
(15) In this altered phenotype the smooth muscle cells proliferate in response to mitogens, synthesize large amounts of extracellular matrix and accumulate lipid, all characteristics of the smooth muscle cell in developing atheroma.
(16) The spectrum ranged from removal of atheroma to subtotal gastric resection.
(17) Cardiac ultrafast computed tomography showed that one half of the patients (21 of 40) had coronary artery calcification, indicating a high incidence of coronary atheroma in this patient population.
(18) Changes in atheroma volume are measured in repeat arteriographic examinations.
(19) Laser angioplasty is used to vaporize atheroma in limb arteries.
(20) The agar model needs further study to determine its limitations, but agar seems to be a useful substitute for atheroma in the study of laser catheter angioplasty.
Atheromatous
Definition:
(a.) Of, pertaining to, or having the nature of, atheroma.
Example Sentences:
(1) Post-operative levels of C3 breakdown products were significantly higher in atheromatic patients than in controls, most likely due to the insertion of dacron arterial prostheses in the first group.
(2) Five thousand patients of atheromatous heart disease, presented as angina pectoris, were studied over a period of five years.
(3) Studies in human postmortem atheromatous arteries and in animal models in vivo indicate that laser balloon angioplasty, by creating a lumen that approximates the size and smooth cylindrical shape of the balloon, should be effective in the treatment of important causes of restenosis.
(4) Percutaneous transluminal atherectomy (ATH) can remove the obstructing atheromatous material and may overcome the limitations of balloon angioplasty for the treatment of occlusive peripheral vascular disease.
(5) A study of hearts removed during medicolegal autopsy of drug addicts after their sudden death demonstrated the constant presence of coronary lesions very similar to common atherosclerosis but remarkable by their magnitude, especially in patients dying at an age when atheromatous disease is relatively rare.
(6) The patient died at the age of 25 years and histopathological examinations of the vessels demonstrated obstructive atheromatous lesions in the medium sized and small arteries of the brain and viscera.
(7) A similar episode of hematuria occurred a year postoperatively and another renal infarction, likely caused by atheromatous embolization, was demonstrable with tomographic and angiographic techniques.
(8) Which investigations have to be performed for diagnosing atheromatous renal failure?
(9) The clinical consequences of familial hypercholesterolemia (FH) result from its metabolic peculiarities that persist from very early childhood, leading to the accumulation of cholesterol in the form of xanthomas in skin and tendons and atheromatous lesions in the arterial wall, in particular, in the aorta and the stem of coronary arteries.
(10) The operative management of large and giant aneurysms is complicated by their typically atheromatous and thick walls, frequent intramural thrombosis with calcification, and broad-based necks that often incorporate perforating and other vital vessels.
(11) Atheromatous embolism disease is a recently defined entity of still to be determined prevalence.
(12) Cultured newborn rat aortic SMC furnish an in vitro model for the study of several aspects of SMC differentiation and possibly of mechanisms leading to the establishment and prevention of atheromatous plaques.
(13) Experimental studies have demonstrated a 30-50% reduction in the development of atheromatous lesions of the aorta in rabbits fed a diet rich in cholesterol when they were treated with nifedipine.
(14) It appears that plasma exchange combined with diet and drug therapy, while not producing regression of existing atheromatous lesions, does retard or prevent further progression.
(15) In this series, the association MCA curve dampened and PTI lower than 0.90 is the evidence of a more than 90% stenosis, except in 2 atheromatous and symptomatic occlusions.
(16) The atheromatous material was for the most part in the core of the thrombus.
(17) Four cases of unilateral digital ischaemia in the upper limb secondary to embolisation from atheromatous plaques in the proximal subclavian artery are presented.
(18) The patients participated in a study aiming to demonstrate whether serum lipid lowering by drugs could influence the development of femoral artery atheromatous disease.
(19) Together the results indicate that in rabbit atheromatous cells, lysosomes are the site of accumulation of intracellular cholesterol in excess of that structurally associated with membranes and that both cytoplasmic droplets and lysosomes are depot sites for cholesteryl esters.
(20) In 9 cases, it was an air embolus, in 4 others an atheromatous embolus.