What's the difference between atom and polybasic?

Atom


Definition:

  • (n.) An ultimate indivisible particle of matter.
  • (n.) An ultimate particle of matter not necessarily indivisible; a molecule.
  • (n.) A constituent particle of matter, or a molecule supposed to be made up of subordinate particles.
  • (n.) The smallest particle of matter that can enter into combination; one of the elementary constituents of a molecule.
  • (n.) Anything extremely small; a particle; a whit.
  • (v. t.) To reduce to atoms.

Example Sentences:

  • (1) It has been conformed that catalase from bovine liver eliminates only the pro R hydrogen atom from ethanol.
  • (2) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
  • (3) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
  • (4) The bond distances of Cu to Cl(1), Cl(2), N(3) and N(3') atoms are 2.299 (1), 2.267 (1), 1.985 (4) and 1.996 (3) A, respectively.
  • (5) The common atoms of the [3Fe-4S] and [4Fe-4S] cores agree within 0.1 A; the three common cysteinyl S gamma ligand atoms agree within 0.25 A.
  • (6) This result was confirmed by atomic absorption spectroscopy, which indicated a stoicheiometry for copper and manganese of approx.
  • (7) The inter-molecular similarity measure used is the number of atoms in the 3-D common substructure (CS) between the two molecules which are being compared.
  • (8) The risks are determined, mainly by expert committees, from the steadily growing information on exposed human populations, especially the survivors of the atomic bombs dropped in Japan in 1945.
  • (9) All N and O atoms except N(3) and O(4') participate in a three-dimensional hydrogen-bonding system.
  • (10) This suggestion is supported by EPR studies, which show that the iron atoms in Fe(III)L-globin are in two low electronic states.
  • (11) The molar refractivity has been shown to be a superior parameter for the description of the activity of sulphonamides than the sum of electronegativities of atoms making up a heterocyclic substituent in the sulphonamide molecule and molecular weight of the substituent.
  • (12) Binding to HSA occurs primarily with the imidazolidine and thiazolidine groups of levamisole as it has been demonstrated by selective changes in the relaxation times and the chemical shifts of the protons attached to the carbon atoms.
  • (13) Each repeat unit contains thirty amino acids and is thought to bind a zinc atom using two cysteines and two histidines as ligands.
  • (14) NADP+ bound at the C8 atom in the adenine moiety proved to be the most efficient ligand whereas that bound at the C3 atom of the ribose moiety was relatively inefficient.
  • (15) This structure is further characterized by approaches of both the carbonyl and the furan O atoms to ring H atoms with separations which are slightly less than the sum of the relevant van der Waals radii.
  • (16) The magnitude of improvement achieved is dependent upon field size, SSD, the atomic number of the foil material, and foil thickness.
  • (17) For the liver enzyme, the logarithm of the inhibition constant was linearly related to the number of carbon atoms in the saturated fatty acids whereas the muscle enzyme, which was generally more strongly inhibited, showed a nonlinear dependence.
  • (18) Results obtained from a such study are here compared with levels obtained from a comparative determination of the metals in the mosses by three other techniques: Differential pulse anodic stripping voltammetry (DPASV), Direct current plasma (atomic emission) spectroscopy (DCPS) and X-ray fluorescence (XRF) spectroscopy.
  • (19) It was hypothesized that the observed activity variation of the paracetamol analogues was based on the relative abilities of these compounds to undergo H atom loss at the phenolic oxygen, and on the relative stabilities of the resulting free-radical species.
  • (20) The resulting family of structures has a mean backbone rmsd of 0.63 A (N, C alpha, C', O atoms), excluding the segments containing residues 45-59 and 84-88.

Polybasic


Definition:

  • (a.) Capable of neutralizing, or of combining with, several molecules of a monacid base; having several hydrogen atoms capable of being replaced by basic radicals; -- said of certain acids; as, sulphuric acid is polybasic.

Example Sentences:

  • (1) The polypeptide does not, however, have a deswelling effect on the tissue; the ultimate reduction in swelling is influenced by the absolute amount of polybase which enters the tissue during the swelling process.
  • (2) Only casein kinase-2 and a spleen tyrosine protein kinase (TPK-III) proved effective, their phosphorylation efficiency being dramatically enhanced by histones and other polybasic peptides while being depressed by 50 microM Ca2+.
  • (3) Within the hypervariable domain of p21K-ras(B), which is not palmitoylated, we have identified a novel plasma membrane targeting signal consisting of a polybasic domain that also acts in combination with the CAAX motif.
  • (4) The polybasic acids trypan blue and its analogue trypan red, bromphenol blue and its analogue bromthymol blue at concentrations of 0.22 mM and ethylenediaminetetra-acetic acid (EDTA) at a concentration of 1 mM are strong inhibitors of the enzyme.3.
  • (5) Mutational analysis of p21ras has shown that plasma membrane targeting requires the combination of a CAAX motif with a polybasic domain of six lysine residues or a nearby palmitoylation site.
  • (6) A method for the isolation of vacuoles based on polybase induced lysis of protoplasts of the cell wall deficient Neurospora crassa slime variant is described.
  • (7) Plasma membrane targeting of p21K-ras(B) requires a CAAX motif and a polybasic domain.
  • (8) The swelling kinetics of polybasic gels consisting of copolymers of methyl methacrylate and dimethylaminoethyl methacrylate are studied in solutions at various acidic pH values, with monoacidic derivatives of acetic acid added as buffers.
  • (9) Polybasic acids affording insoluble salts were evaluated for their ability to form drug:acid:metal complexes with the polyvalent metal ions, Zn++, Al+++, Mg++ and Ca++.
  • (10) Modification of BHV tissue was obtained by covalently binding protamine sulfate, a polybasic peptide, via glutaraldehyde.
  • (11) Potassium chloride in high concentrations and calcium chloride in low concentrations inhibited polybase induced lysis of spheroplasts by preventing or even reversing the polybase adsorption.
  • (12) Profilin with one covalently attached actin CNBr peptide was purified by gel filtration followed by gel electrophoresis and electroblotting on polybase-coated glass-fiber membranes.
  • (13) Modification of BHV tissue was obtained by covalently binding protamine sulfate, a polybasic peptide, via formaldehyde and subsequent glutaraldehyde tissue crosslinking.
  • (14) With labeled proteins used as models, it is found that the transport proceeds at very low rates, requires little energy, and is markedly enhanced by polybasic compounds.
  • (15) The polybasic macromolecules DEAE-dextran (diethylaminoethyl-dextran, molecular weight 500000) and poly-DL-lysine (molecular weight 30000-70000) were absorbed with a high affinity by spheroplasts of Candida utilis and subsequently, induced lysis.
  • (16) The differences in accumulation levels of Mn2+ and Sr2+ attained after prolonged incubation are completely abolished in cells of which the plasmamembrane has been permeabilized with the polybase DEAE-dextran under isotonic conditions.
  • (17) Adsorption of polybases was rapidly completed even at 0 degrees C; however, with small doses, lysis was poor at 0-12 degrees C and extensive at temperatures above 12 degrees C. This permitted the completion of adsorption before initiating lysis.
  • (18) The results indicate that the phosphorylated form of PGKARKKSSC-geranylgeranyl stoichiometrically interacts with smg p21 GDS, that the presence of the geranylgeranyl moiety is essential for, but not sufficient for, the smg p21 GDS action, and that the presence of the methyl moiety, removal of the three C-terminal amino acids, and the presence of the polybasic amino acids also affect the smg p21 GDS action.
  • (19) Vacuoles isolated from polybase lysed spheroplasts still contained large pools of soluble amino acids, and their ability to transport arginine specifically is a further indication of their functional integrity.
  • (20) It is proposed that the cationic C3a molecule activates rat mast cells in a secretory and nonlytic manner by a nonspecific mechanism similar to that of other polybasic compounds.

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