(v. t.) To make thin or slender, as by mechanical or chemical action upon inanimate objects, or by the effects of starvation, disease, etc., upon living bodies.
(v. t.) To make thin or less consistent; to render less viscid or dense; to rarefy. Specifically: To subtilize, as the humors of the body, or to break them into finer parts.
(v. t.) To lessen the amount, force, or value of; to make less complex; to weaken.
(v. i.) To become thin, slender, or fine; to grow less; to lessen.
(a.) Alt. of Attenuated
Example Sentences:
(1) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
(2) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
(3) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
(4) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
(5) These results indicate that during IPPV the increased Pcv attenuates the pressure gradient for venous return and decreases CO and that the compensatory increase in Psf is caused by a blood shift from unstressed to stressed blood volume.
(6) Mild, significant improvement was noted in one of the hearing components, "attenuation," and an adverse effect was shown on "distortion," owing to noise.
(7) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(8) Genetic regulation of the ilvGMEDA cluster involves attenuation, internal promoters, internal Rho-dependent termination sites, a site of polarity in the ilvG pseudogene of the wild-type organism, and autoregulation by the ilvA gene product, the biosynthetic L-threonine deaminase.
(9) Pharmacodynamic relationships are not well established for other therapeutic effects of theophylline, such as attenuation of pharmacologically induced bronchoconstriction.
(10) Propranolol, 0.85 X 10(-6) M, did not significantly depress the ouabain-enhanced rate of phase 4 depolarization but did attenuate the response to epinephrine through beta blockade.
(11) After large bowel removal, there was impaired glucose tolerance and attenuated plasma insulin secretion.
(12) Studies were conducted in isolated, buffer-perfused rat lungs to determine if prostaglandin (PG) E1 attenuated pulmonary edema provoked by hydrogen peroxide (H2O2).
(13) The toxins preferentially attenuate a slow phase of KCl-evoked glutamate release which may be associated with synaptic vesicle mobilization.
(14) The Northern quahaug and a strain of the type 1 attenuated poliovirus were used as the working model.
(15) Our dynamic study indicated that: 1) a bolus injection of contrast medium with our method of CTA (CTA-B) produced an attenuation difference between liver and tumor which was about double that obtained with standard methods for CTA, and 2) marked tumor-liver attenuation differences (above 20 HU) persisted for more than 60 s in CTA-B and for not more than 20 s with conventional methods for CTA.
(16) It appears that the viscosity of the arterial wall must be the major source of attenuation in the larger arteries, while the viscosity of the blood plays a significant role only in the smaller vessels.
(17) Fluid movement out of the ICF space attenuated the decrease in the ECF space.
(18) We show that the two mutants (A44 and A46) affect attenuator control by different mechanisms.
(19) The type I cells are squamous and give off attenuated sheets of cytoplasm which spread widely over the septal surface; these sheets contain few organelles.
(20) A sequence of seven pairings of chili-flavored diet with prompt recovery from thiamine deficiency did significantly attenuate the innate aversion and may have induced a chili preference in at least one case.
Lower
Definition:
(a.) Compar. of Low, a.
(a.) To let descend by its own weight, as something suspended; to let down; as, to lower a bucket into a well; to lower a sail or a boat; sometimes, to pull down; as, to lower a flag.
(a.) To reduce the height of; as, to lower a fence or wall; to lower a chimney or turret.
(a.) To depress as to direction; as, to lower the aim of a gun; to make less elevated as to object; as, to lower one's ambition, aspirations, or hopes.
(a.) To reduce the degree, intensity, strength, etc., of; as, to lower the temperature of anything; to lower one's vitality; to lower distilled liquors.
(a.) To bring down; to humble; as, to lower one's pride.
(a.) To reduce in value, amount, etc. ; as, to lower the price of goods, the rate of interest, etc.
(v. i.) To fall; to sink; to grow less; to diminish; to decrease; as, the river lowered as rapidly as it rose.
(v. i.) To be dark, gloomy, and threatening, as clouds; to be covered with dark and threatening clouds, as the sky; to show threatening signs of approach, as a tempest.
(v. i.) To frown; to look sullen.
(n.) Cloudiness; gloominess.
(n.) A frowning; sullenness.
Example Sentences:
(1) These factors might account for the lower systemic bioavailability of these compounds.
(2) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(3) In this study of ten consecutive patients sustaining molten metal injuries to the lower extremity who were treated with excision and grafting, treatment with compression Unna paste boot was compared with that with conventional dressing.
(4) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(5) Homozygotes have sparse greasy fur and lower viability and fertility than normal littermates.
(6) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
(7) On the other hand, the LAP level, identical in preterms and SDB, is lower than in full-term infants but higher than in adults.
(8) It is suggested that the Japanese may have lower trabecular bone mineral density than Caucasians but may also have a lower threshold for fracture of the vertebrae.
(9) Spontaneous locomotor activity was lower in naloxone-infused rats on day 3 only.
(10) After 55 days of unrestricted food availability the body weight of the neonatally deprived rats was approximately 15% lower than that of the controls.
(11) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
(12) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(13) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(14) Side effect incidence in patients treated with the paracetamol-sobrerol combination (3.7%) was significantly lower than that observed in subjects treated with paracetamol (6.1% - P less than 0.01), salicylics (25.1% - P less than 0.001), pyrazolics (12.6% - P less than 0.001), propionics (20.3%, P less than 0.001) or other antipyretics (17.9% - P less than 0.001).
(15) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(16) Diltiazem monotherapy effectively lowered blood pressure in 60% of patients at 8 weeks.
(17) Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
(18) Anesthetized sheep (n = 6) previously prepared with a lung lymph fistula underwent 2 hr of tourniquet ischemia of both lower limbs.
(19) Nicardipine lowered systolic and diastolic blood pressure to normal, plasma aldosterone was reduced and serum potassium levels were increased.
(20) The overall recoveries of activated ER following chromatography on DEAE-cellulose were significantly lower than the recoveries of the nonactivated ER, 71 and 85%, respectively.