(1) The 27- and 15-kDa proteins were detected exclusively on the luminal side of mature, apical AUMs.
(2) The emergency service tend to victims of the Aum Shinrikyo sarin attack on Tokyo's subway in 1995.
(3) Using immunogold localization techniques, we showed that in cultured urothelial colonies--which are known to lack mature AUM plaques--UGP85 is distributed relatively uniformly on the apical surface of some differentiated cells.
(4) VX has been used in an assassination before, in 1995 when the Japanese Aum Shinrikyo cult sprayed it on a businessman it believed was spying on its activities.
(5) 111, 1207-1216), translocates from one side of the membrane to another during AUM maturation, (iii) indicate that uroplakin III may play a different structural role than uroplakins I and II in AUM formation, and (iv) establish the three uroplakins as markers for an advanced stage of urothelial differentiation.
(6) In the meantime, many superficial cells in cultured urothelial colonies make uroplakin I, a 27 x 10(3) Mr protein subunit of the asymmetrical unit membrane (AUM) characteristic of urothelial (superficial) umbrella cells.
(7) For example, the PRI’s coordinated engagement on managing risks in hydraulic fracturing, includes 41 institutional investors with a total AUM of $5.1tn.
(8) The identification of these AUM-associated and -related proteins, plus the availability of a culture system capable of synthesizing and processing some of these molecules, offer new opportunities for studying the detailed structure, assembly, and function of asymmetrical unit membrane.
(9) Based on complex formation data, we provisionally name the 15-kD protein uroplakin II; additional data will be required to determine whether this and the 47-kD protein are integral parts of AUM.
(10) The luminal surface of mammalian urothelium is covered with numerous plaques (also known as the asymmetric unit membrane or AUM) composed of semi-crystalline, hexagonal arrays of 12-nm protein particles.
(11) Two of seven EBV-transformed B-cell lines tested (ORSON and AUM cells) in response to BCGF-II exhibited augmentation of proliferation and cell surface Tac Ag expression.
(12) Using gradient centrifugation and detergent wash, we purified milligram quantities of AUMs which, interestingly, contained three major proteins (15, 27, and 47 kDa) that appeared to be identical to the three immunoaffinity purified, putatively AUM-associated proteins that we described earlier (Yu, J., Manabe, M., Wu, X.-R., Xu, C., Surya, B., and Sun, T.-T. (1990) J.
(13) Using monospecific antibodies to these three proteins, we showed that they were all restricted to the superficial urothelial cells and were AUM-associated.
(14) The initiative now has 1,260 signatories representing $45tn in assets under management (AUM).
(15) This suggests an unusual translocation of the AE31 epitope during AUM maturation; more data are required, however, to substantiate this interpretation.
(16) The Aum Shinrikyo sect in Japan was able to manufacture sarin gas and release it on the metro in Tokyo in 1995.
(17) Asymmetric unit membrane (AUM) is a component of the luminal membrane of urinary bladder in many species.
(18) In cytoplasmic vesicles containing immature AUM, the AE31 epitope is detected in patches on the cytoplasmic side, but in mature, apical AUM it is detected exclusively on the luminal side.
(19) But there are 'Japanese' aspects as well – especially aspects of Japan's history and recent social changes, such as echoes in the second world war, Aum Shinrikyo, the Kobe earthquake, (and) the economic decline of the past two decades.
(20) North Korea's use of nerve agent in murder sends a deliberate signal to foes Read more Months before killing about a dozen commuters and severely injuring dozens more in Tokyo with sarin, another kind of nerve gas, in March 1995, the Aum Shinrikyo Truth cult tried VX on at least three victims, killing one, whom cult members believed was a police informant.
Tum
Definition:
Example Sentences:
(1) The DNA of tum- variant P35 was transfected into P815 cell line P1.HTR.
(2) Mutagen treatment of mouse P815 tumor cells produces tum- variants that are rejected by syngeneic mice because these variants express new surface antigens.
(3) We have isolated human and bovine cDNA clones that encode the homologs of the mouse tum- antigen P198.
(4) apparently not to be due to any mutation such as typ, tup, tmp, per or tum.
(5) The diversity of these antigens appears to be very large, like that of the tum- antigens.
(6) Immunization of rats with one C variant (C8) tum- cells did not protect them against either metastases or local growth of the implanted tumours.
(7) This antigenic pattern is similar to that found on teratocarcinoma tum- variants.
(8) Each of these "tum-" variants is rejected in syngeneic mice and stimulates the production of immune memory cells (self-protection).
(9) Mutagen treatment of P815 tumour cells produces tum- variants that are rejected by syngeneic mice because they express new transplantation antigens.
(10) The cells carrying the mutant alleles have impaired tumorigenicity compared with their progenitors due to in vivo induction of a cytotoxic T-cell response specific for tum- antigens.
(11) The drug susceptibility pattern of the strains revealed that there was no significant association of resistance between Tum and streptomycin or rifampicin or ethambutol or ethionamide or isoniazid.
(12) The sequence of this gene and that of two other tum- genes are totally unrelated with each other and with any sequence presently recorded in data banks.
(13) Our results suggest that the procedure of using a mutagen in order to generate tum- variants carrying new transplantation antigens may be generally applicable to cancer cells.
(14) Rumbling tums can be quietened at plenty of places to eat round the estate, until 5.30pm.
(15) Although tum+ clones grew in normal mice, immune mice were able to prevent the growth of tum+ clones with high levels of H-2 antigens.
(16) We have analyzed the effects of high doses of cyclophosphamide (Cy) on primary and secondary antitumor immune response against immunogenic (tum-) variants of Lewis lung carcinoma (3LL) treated in vitro with UV light.
(17) The tum- allele differs from its normal counterpart by a point mutation.
(18) Mongolian gerbils (Meriones unguiculatus) of Tumble Blook (TUM) and Japan Medical Science (JMS) stocks were compared with regard to susceptibility to Leptospira interrogans serovar copenhageni.
(19) The tum- clones are therefore unable to generate tumors in syngeneic mice because they elicit an immune rejection response.
(20) No H-2 antigens were found on the cell surface of the parental BL6 clones, whereas all tum- clones from the BL6T2 line expressed high levels of H-2 antigens.