(v. t.) To render authentic; to give authority to, by the proof, attestation, or formalities required by law, or sufficient to entitle to credit.
(v. t.) To prove authentic; to determine as real and true; as, to authenticate a portrait.
Example Sentences:
(1) Moreover in MIT-1, the size of the novel polypeptide was not that predicted of the precursor (44.9 kDa) but was about 39 kDa, the same size as the authentic GS gamma polypeptide in CYT-4.
(2) In the absence of an authentic target for the MASH proteins, we examined their DNA binding and transcriptional regulatory activity by using a binding site (the E box) from the muscle creatine kinase (MCK) gene, a target of MyoD.
(3) Except in the case of the phenolic metabolite, structures were confirmed by direct comparison of electron impact mass spectra and chromatographic behaviour with those of authentic samples.
(4) These latter cardiovascular changes imply that the endotracheal pressure variations are the reflection of authentic inspiratory movements under the influence of the central nervous system.
(5) Several in vitro transcripts both larger and smaller than the authentic transcript were seen; presumably, these transcripts result from adventitious promoterlike elements in adjacent chlamydial DNA and may be responsible for the expression of the gene in E. coli.
(6) The amidolytic activity of [R275G]t-PA was comparable to that of authentic one-chain t-PA, and so was the activity of [R275L,K277L]t-PA, in which additional substitution of lysine residue 277 was carried out.
(7) 15, 961-969] prompted an investigation to confirm its authenticity.
(8) The authentic dolichyl phosphates (Dol-7-P, Dol-9-P, and Dol-11-P) were assayed relative to the natural dolichyl phosphate mixture from pig liver as acceptors for transglycosylation from nucleoside diphosphate sugars (glucose, mannose) by standardized membrane vesicle preparations from plants (Volvox) and animals (liver).
(9) The polypeptide encoded by the cDNA was synthesized by in vitro transcription and translation and identified by its comigration with authentic plakoglobin in two-dimensional gel electrophoresis.
(10) An authentic poly(ADP-ribose), with a mean chain length of approximately 30 ADP-ribose units, produced significant inhibition of the neutral protease isolated from macrophage chromatin.
(11) Fructose 2-phosphorothioate 6-phosphate was 10-100-fold less potent than authentic fructose 2,6-bisphosphate in stimulating 6-phosphofructo-1-kinase and pyrophosphate:fructose 6-phosphate phosphotransferase, but about 10 times more potent in inhibiting fructose 1,6-bisphosphatase.
(12) The separated cholesterol oxides were identified by comparing with authentic standards.
(13) Radioimmunoassays carried out on acidic extracts of the same organs confirm the molecular results and lead us to conclude to the presence of substances strongly related to MK in the ovotestis as well as in the circumoesophageal ganglia (COG), and to ascertain that the MK-positive tentacular collar cells do not contain authentic MK.
(14) In return, the government would finger freelance or rival operators so that the authorities could give the impression of an authentic enforcement operation.
(15) Comparison of elution patterns of authentic cholesterol and cholesteryl esters revealed that a mu Bondasphere reverse-phase C8 (300-A) column was more suitable than a corresponding reverse-phase C4 or C18 column in terms of rapidity and sensitivity.
(16) This polypeptide reacted specifically with rabbit antisera made against synthetic peptides corresponding to exposed regions of authentic p14 as predicted from the S1 cDNA sequence.
(17) An aesthetic of authenticity guides his approach to movie-making.
(18) But if there's a piece you particularly enjoyed, or found interesting or useful, please add a comment below or tweet us: @GdnSocialCare At the start of the year, the BBC screened fly-on-the-wall documentary series Protecting Our Children , an authentic portrayal of the difficult decisions and situations social workers face every day.
(19) I don’t think this ghostwritten book undermines her authenticity elsewhere.
(20) It is concluded that authentic hCG does occur in human seminal plasma, but only in about a third of samples.
Substantiate
Definition:
(v. t.) To make to exist; to make real.
(v. t.) To establish the existence or truth of by proof or competent evidence; to verify; as, to substantiate a charge or allegation; to substantiate a declaration.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.