(1) The current studies suggest that the autochthonous mammary tumor cells, independent of estrogen for cell growth, were still inducible for casein gene expression in vitro and in vivo by appropriate hormones.
(2) A wide but discontinuous distribution of the snail on the north coast of Haiti is confirmed (no autochthonous infections with S. mansoni have been reported).
(3) Furthermore, it was also confirmed that TIL-LAK cells could be induced in autochthonous mouse tumor systems and human gastric tumor systems.
(4) Neither patients' sera nor peripheral blood leukocytes showed significant cytotoxicity against autochthonous tumour cells in microtitre assays.
(5) Neutrophils and macrophages first appeared following transplantation of autochthonous tumor.
(6) Aerobic microorganisms are constantly entering the digestive tract with food, but colonization is resisted by autochthonous anaerobic flora (microbial colonization resistance) and by host-related factors (physiologic colonization resistance).
(7) The mitogenic response of some but not all hyporesponsive spleens from autochthonous tumor bearers was restored after removal of phagocytic macrophages.
(8) When different methods of treatment of the stimulating autochthonous blasts were compared with untreated cells, mitomycin C gave the highest stimulation indices 2 out of 3 tests.
(9) Two tumor models were selected: (a) autochthonous, MNU-induced mammary carcinoma and (b) transplanted rat leukemia L5222.
(10) The promising activities of these new platinum-linked phosphonic acids in autochthonous rat colorectal carcinoma and in human colorectal cancer cell lines warrant further investigations of compounds of this class to elucidate their role in the treatment of colorectal cancer.
(11) Our results demonstrate that anti-inflammation is probably not required for emergence and growth of these autochthonous tumors, that strongly immunogenic tumors may actually enhance macrophage responses and that the effect of tumor bearing on macrophage inflammation is a characteristic of the tumor, including its site and host of origin, its immunogenicity and its transplant generation.
(12) Among 154 different, MCA-induced mouse sarcomas, the immunogenicities of those tumors that had had the shortest original latencies in their autochthonous hosts were of an intermediate level with relatively little scatter.
(13) Antibody-dependent, cell-mediated cytotoxicity in the Moloney sarcoma virus (MSV) system was analyzed in terms of the ability of autochthonous antibody to induce or potentiate cytotoxicity by lymphocytes from animals infected with MSV.
(14) Sera of eight unselected adult patients with acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement-dependent cytotoxicity against autochthonous peripheral white blood cells from the acute leukemia stage and from the remission stage, respectively.
(15) The antitumor activity of the cell-wall skeleton (CWS) of Propionibacterium acnes C7 was examined by using transplantable tumors in syngeneic mice and in guinea pigs, and autochthonous tumors in mice.
(16) Serums from three patients with renal cell carcinoma, one without any recurrent tumor and two with metastases, appear to significantly block the autochthonous and allogeneic lymphocyte cytotoxicity.
(17) This expression of metastatic potential was significantly different (p less than 0.05) from 14 primary cancers without autochthonous host metastases.
(18) Cells from autochthonous mouse mammary carcinomas which display estrogen-independent growth in vivo were studied for their hormonal responses in primary culture.
(19) Autochthonous, homologous, and heterologous immunizations of chickens and rats did not produce a detectable antibody response to a virus-specific tumor surface antigen.
(20) The lysis pattern of autochthonous M. tuberculosis is characterized by a prevalence of sensitivity to phages DS6A, GS4E, BG1, and D34.