(n.) A handsome Asiatic tree (Melia azedarach), common in the southern United States; -- called also, Pride of India, Pride of China, and Bead tree.
(n.) The bark of the roots of the azedarach, used as a cathartic and emetic.
Example Sentences:
(1) A glycopeptide isolated from the high plant Melia azedarach L. (meliacine) inhibits the in vitro replication of several RNA and DNA animal viruses.
(2) Abolition of libido in 100% males by leaf extracts of D. embryopteris and M. azedarach and in 60% of males by extract of C. tomentosa preclude these plants for antifertility use.
(3) A partially purified plant inhibitor (Meliacin) isolated from Melia azedarach L induced in cells a refractory state to virus infection.
(4) Melianoninol (I), melianol (II), melianone (III), meliandiol (IV), vanillin (V) and vanillic acid (VI) were isolated from the fruits of Melia azedarach L..
(5) It is concluded that an antiviral factor devoid of toxicity exists in M. azedarach L extracts, which exhibited a broad spectrum of antiviral activity.
(6) Partially purified extracts from leaves of Melia azedarach L. (MA) exert a broad range of antiviral effects on DNA and RNA viruses.
(7) A partially purified extract from fresh green leaves of Melia azedarach L prevents the replication of Pseudorabies virus (Suid herpesvirus, (PrV)) in Vero cells.
(8) Treatment of neonatal mice with an antiviral factor, (AVF), obtained from the leaves of Melia azedarach L. protected them against lethal encephalitis caused by Tacaribe virus inoculation.
(9) We have investigated a pollen widely spread in our province, called Melia azedarach and have demonstrated its property of inducing allergic respiratory disease.
(10) Evidence is presented for the structure of a new limonoid glycoside, 6-acetoxy-11 alpha-hydroxy-7-oxo-14 beta, 15 beta-epoxymeliacin-1,5-diene-3-O-alpha-L-rhamnopyranoside, which occurs together with salannin and meldenin in the seeds of Melia azedarach.
(11) Crude extracts from fresh green leaves of Melia azedarach L contain an antiviral factor (FAV) able to inhibit the replication of several animal viruses, e.g.
Margosa
Definition:
(n.) A large tree of genus Melia (M. Azadirachta) found in India. Its bark is bitter, and used as a tonic. A valuable oil is expressed from its seeds, and a tenacious gum exudes from its trunk. The M. Azedarach is a much more showy tree, and is cultivated in the Southern United States, where it is known as Pride of India, Pride of China, or bead tree. Various parts of the tree are considered anthelmintic.
Example Sentences:
(1) Seizures occurred in all animals given valproic acid, margosa oil and 4-pentenoic acid, and in 25% of those given 5% glucose solution + anti-diuretic hormone.
(2) While glucose and carnitine supplements appear to be beneficial, the other modes of therapy do not seem to hold much promise in the treatment of Reye-like syndrome in the margosa-oil-induced animal model.
(3) A statistically significant increase in brain water content was observed following injection of 5% glucose solution, valproic acid, acetyl salicylic acid, calcium hopantenate, margosa oil, 4-pentenoic acid, linolenate and arachidonate.
(4) Linoleic acid, a polyunsaturated fatty acid, is a constituent of margosa oil which has been implicated as a cause of Reye's syndrome (RS) in infants.
(5) Margosa oil (MO), a fatty acid-rich extract of the seeds of the neem tree and a reported cause of Reye's syndrome, has been used in the induction of an experimental model of Reye's syndrome in rats.
(6) Evaluation of coenzyme Q10 and carnitine on histopathologic parameters in the liver after a sublethal dose of margosa oil showed no obvious ameliorating effect on liver pathology.
(7) Margosa oil (MO), a long-chain fatty acid compound, has been shown to cause a Reye-like syndrome with death from hepatoencephalopathy, in children in Malaysia and India.
(8) We report here two infants with Margosa Oil poisoning presenting with encephalopathy.
(9) Margosa Oil is an extract of the seed of the Neem tree and is widely used as a traditional medicine by Indians in India, Sri Lanka, Burma, Thailand, Malaysia and Indonesia.
(10) This accords with the reports of reduced glutamic dehydrogenase activities in the livers of both patients with Reye's syndrome and rats treated with margosa oil.
(11) Changes in the mitochondria, ribosomes and endoplasmic reticulum were unaltered from the groups treated with margosa oil alone.
(12) Margosa Oil causes toxic encephalopathy particularly in infants and young children.
(13) Glucose and steroids have been used in the treatment of children with Reye's syndrome, while carnitine and coenzyme Q10 have been the subject of some recent studies which suggest that these agents may have a role in the treatment of Reye's syndrome and Reye-like syndrome due to margosa oil poisoning.
(14) Following reports of a Reye-like syndrome in children resulting from Margosa oil (MO) ingestion, we administered MO to laboratory rats in an attempt to produce an animal model of Reye's syndrome.
(15) These caveats were overcome by evaluation of these four treatment modalities in an established margosa-oil-induced animal model of Reye's syndrome.