(1) Responses of bovine adrenal capillary endothelial cells (BACE) on treatment with transforming growth factor beta 1 (TGF-beta 1) have been characterized and tested for sensitivity to inactivation of pertussis toxin-sensitive G-proteins.
(2) Analysis of p34cdc2 activity in BACE cells revealed potent inhibition of p34cdc2 histone H1 kinase activity by TGF-beta 1.
(3) Angiogenin modulates mitogenic stimuli in bovine adrenal capillary endothelial (BACE), rat aortic smooth muscle (RASM), and fibroblast (3T3) cells.
(4) Further investigation revealed that pertussis toxin treatment of BACE cells had no effect on TGF-beta 1-stimulated elevation of steady state mRNA levels for collagen type 1 (alpha 1(1) or alpha 2(1)) or for TGF-beta 1.
(5) The addition of SP to serum-free cultured endothelial cells, isolated from bovine adrenals (BACE) and from human umbilical cord veins (HUVE), increased proliferation of both cell lines in a concentration-dependent manner with maximal activity at 10(-8) M (BACE) and 10(-10) M (HUVE).
(6) Pertussis toxin treatment enhanced both inhibition of BACE cell [3H]methylthymidine uptake and remodeling of BACE monolayers by TGF-beta 1.
(7) TGF-beta 1 elicited growth inhibition, monolayer remodeling, elevation of steady state mRNA levels for collagen type 1 (alpha 1(1) and alpha 2(1)) and TGF-beta 1, and inhibition of p34cdc2 histone H1 kinase activity in BACE cells.
(8) Consistent with suppression of p34cdc2 activation, pertussis toxin also caused substantial inhibition of mitogen-stimulated BACE cell [3H]methylthymidine uptake.
(9) Thus, it enhances the mitogenic effect of certain conditioned media on RASM and 3T3 cells, but it inhibits the mitogenic effect on BACE cells.
Bice
Definition:
(n.) Alt. of Bise
Example Sentences:
(1) During subsequent assessments, agrammatic aphasics reveal on a metalinguistic judgment task their significant difficulty appreciating the grammatical form class of "bice"; on an object classification task, fluent aphasics are significantly impaired in their classification of bice-colored objects as "bice."
(2) (3) Whereas there was a positive relationship, in the data for the controls, between measures of syntactic and semantic awareness concerning "bice", there was no such relationship in the Korsakoffs data.
(3) In the context of drawing pictures with a number of felt pens identical in all respects except color, agrammatic Broca's aphasics and fluent aphasics were exposed to the new word "bice," an adjective referring to the dark green portion of the color spectrum.
(4) Specifically, on successive exposures to "bice," both Broca's aphasics and fluent aphasics exhibit progressively more accurate hypotheses for identifying a bice-colored object.
(5) The conceptual interpretation that the Korsakoffs developed for "bice" differed in three respects from the one that the controls developed.
(6) Dr. Bice was convinced that oral contraceptives played a significant part in the development of the patient's illness.
(7) Six Korsakoffs amnesics, three mixed amnesics, and eight normal controls were taught the meaning of "bice", the word for a particular shade of blue-green.