(1) Responses of bovine adrenal capillary endothelial cells (BACE) on treatment with transforming growth factor beta 1 (TGF-beta 1) have been characterized and tested for sensitivity to inactivation of pertussis toxin-sensitive G-proteins.
(2) Analysis of p34cdc2 activity in BACE cells revealed potent inhibition of p34cdc2 histone H1 kinase activity by TGF-beta 1.
(3) Angiogenin modulates mitogenic stimuli in bovine adrenal capillary endothelial (BACE), rat aortic smooth muscle (RASM), and fibroblast (3T3) cells.
(4) Further investigation revealed that pertussis toxin treatment of BACE cells had no effect on TGF-beta 1-stimulated elevation of steady state mRNA levels for collagen type 1 (alpha 1(1) or alpha 2(1)) or for TGF-beta 1.
(5) The addition of SP to serum-free cultured endothelial cells, isolated from bovine adrenals (BACE) and from human umbilical cord veins (HUVE), increased proliferation of both cell lines in a concentration-dependent manner with maximal activity at 10(-8) M (BACE) and 10(-10) M (HUVE).
(6) Pertussis toxin treatment enhanced both inhibition of BACE cell [3H]methylthymidine uptake and remodeling of BACE monolayers by TGF-beta 1.
(7) TGF-beta 1 elicited growth inhibition, monolayer remodeling, elevation of steady state mRNA levels for collagen type 1 (alpha 1(1) and alpha 2(1)) and TGF-beta 1, and inhibition of p34cdc2 histone H1 kinase activity in BACE cells.
(8) Consistent with suppression of p34cdc2 activation, pertussis toxin also caused substantial inhibition of mitogen-stimulated BACE cell [3H]methylthymidine uptake.
(9) Thus, it enhances the mitogenic effect of certain conditioned media on RASM and 3T3 cells, but it inhibits the mitogenic effect on BACE cells.
Face
Definition:
(n.) The exterior form or appearance of anything; that part which presents itself to the view; especially, the front or upper part or surface; that which particularly offers itself to the view of a spectator.
(n.) That part of a body, having several sides, which may be seen from one point, or which is presented toward a certain direction; one of the bounding planes of a solid; as, a cube has six faces.
(n.) The principal dressed surface of a plate, disk, or pulley; the principal flat surface of a part or object.
(n.) That part of the acting surface of a cog in a cog wheel, which projects beyond the pitch line.
(n.) The width of a pulley, or the length of a cog from end to end; as, a pulley or cog wheel of ten inches face.
(n.) The upper surface, or the character upon the surface, of a type, plate, etc.
(n.) That part of the head, esp. of man, in which the eyes, cheeks, nose, and mouth are situated; visage; countenance.
(n.) Cast of features; expression of countenance; look; air; appearance.
(n.) Ten degrees in extent of a sign of the zodiac.
(n.) Maintenance of the countenance free from abashment or confusion; confidence; boldness; shamelessness; effrontery.
(n.) Presence; sight; front; as in the phrases, before the face of, in the immediate presence of; in the face of, before, in, or against the front of; as, to fly in the face of danger; to the face of, directly to; from the face of, from the presence of.
(n.) Mode of regard, whether favorable or unfavorable; favor or anger; mostly in Scriptural phrases.
(n.) The end or wall of the tunnel, drift, or excavation, at which work is progressing or was last done.
(n.) The exact amount expressed on a bill, note, bond, or other mercantile paper, without any addition for interest or reduction for discount.
(v. t.) To meet in front; to oppose with firmness; to resist, or to meet for the purpose of stopping or opposing; to confront; to encounter; as, to face an enemy in the field of battle.
(v. t.) To Confront impudently; to bully.
(v. t.) To stand opposite to; to stand with the face or front toward; to front upon; as, the apartments of the general faced the park.
(v. t.) To cover in front, for ornament, protection, etc.; to put a facing upon; as, a building faced with marble.
(v. t.) To line near the edge, esp. with a different material; as, to face the front of a coat, or the bottom of a dress.
(v. t.) To cover with better, or better appearing, material than the mass consists of, for purpose of deception, as the surface of a box of tea, a barrel of sugar, etc.
(v. t.) To make the surface of (anything) flat or smooth; to dress the face of (a stone, a casting, etc.); esp., in turning, to shape or smooth the flat surface of, as distinguished from the cylindrical surface.
(v. t.) To cause to turn or present a face or front, as in a particular direction.
(v. i.) To carry a false appearance; to play the hypocrite.
(v. i.) To turn the face; as, to face to the right or left.
(v. i.) To present a face or front.
Example Sentences:
(1) Some commentators have described his ship, now facing more delays after a decade in development, as little more than a Heath Robinson machine.
(2) I hope this movement will continue and spread for it has within itself the power to stand up to fascism, be victorious in the face of extremism and say no to oppressive political powers everywhere.” Appearing via videolink from Tehran, and joined by London mayor Sadiq Khan and Palme d’Or winner Mike Leigh, Farhadi said: “We are all citizens of the world and I will endeavour to protect and spread this unity.” The London screening of The Salesman on Sunday evening wasintended to be a show of unity and strength against Trump’s travel ban, which attempted to block arrivals in the US from seven predominantly Muslim countries: Iran, Iraq, Libya, Sudan, Somalia, Syria and Yemen.
(3) The playing fields on which all those players began their journeys have been underfunded for years and are now facing a renewed crisis because of cuts to local authority budgets.
(4) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(5) Former lawmaker and historian Faraj Najm said the ruling resets Libya “back to square one” and that the choice now faced by the Tobruk-based parliament is “between bad and worse”.
(6) The dilemmas faced by the genetic counsellor are discussed in this variable autosomal dominant condition.
(7) The law would let people find out if partners had a history of domestic violence but is likely to face objections from civil liberties groups.
(8) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(9) "We presently are involved in a number of intellectual property lawsuits, and as we face increasing competition and gain an increasingly high profile, we expect the number of patent and other intellectual property claims against us to grow," the company said.
(10) In subsequent experiments, both components were found to be significant and additive predictors of face recognition with no residual effect of typicality.
(11) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(12) The size of Florida makes the kind of face-to-face politics of the earlier contests impossible, requiring instead huge ad spending.
(13) The lymphocyte-specific phosphoprotein LSP1 associates with the cytoplasmic face of the plasma membrane and with the cytoskeleton.
(14) Newspapers and websites across the country have been reporting the threat facing nursery schools for weeks, from Lancashire to Birmingham and beyond.
(15) When faced with a big dilemma, the time-honoured tradition of politicians is to order an inquiry, and that is what Browne expects.
(16) Taking into account the calculated volume and considering the triangular image as one face of the particle, it is suggested that eIF-3 has the shape of a flat triangular prism with a height of about 7 nm and the above-mentioned side-lengths.
(17) What is Obama doing about the prejudice and violence faced by brown people here at home?
(18) "Monasteries and convents face greater risks than other buildings in terms of fire safety," the article said, adding that many are built with flammable materials and located far away from professional fire brigades.
(19) Cameron, who faces intense political pressure from the UK Independence party in the runup to the 2014 European parliamentary elections, believes voters will need to be consulted if the EU agrees a major treaty revision in the next few years.
(20) Uruguay's coach, Oscar Tabárez, had insisted yesterday that his player should face only a one-match ban.