(n.) The column of bones in the back which sustains and gives firmness to the frame; the spine; the vertebral or spinal column.
(n.) Anything like , or serving the purpose of, a backbone.
(n.) Firmness; moral principle; steadfastness.
Example Sentences:
(1) A method for the introduction of side chains containing isonitrile (isocyanide, functional group) on the backbone of polysaccharides and other hydroxylic polymers was developed.
(2) The chromophore of octopus rhodopsin is 11-cis retinal, linked via a protonated Schiff base to the protein backbone.
(3) An unprincipled coward with the backbone of an amoeba."
(4) The Pr(III)-induced shifts for several resolved nonexchangeable backbone proton resonances were compared with calculated shifts using the known x-ray structure.
(5) Here we present images of polydeoxyadenylate molecules aligned in parallel, with their bases lying flat on a surface of highly oriented pyrolytic graphite and with their charged phosphodiester backbones protruding upwards.
(6) These data suggest that the somnogenic actions of these lipid A analogs depend on the acylation or phosphorylation pattern and backbone structures of the molecules.
(7) The resulting family of structures has a mean backbone rmsd of 0.63 A (N, C alpha, C', O atoms), excluding the segments containing residues 45-59 and 84-88.
(8) wt polypeptide backbone, modified by an endoglycosidase F-sensitive carbohydrate moiety.
(9) The backbone dynamics of Ca(2+)-saturated recombinant Drosophila calmodulin has been studied by 15N longitudinal and transverse relaxation experiments, combined with 15N(1H) NOE measurements.
(10) A central eight-stranded beta-pleated sheet is the main feature of the polypeptide backbone folding in dihydrofolate reductase.
(11) To investigate the topochemical preference of backbone and side chains, unusual amino acids, including beta-methylphenylalanine7 or 11, beta-methyltryptophan8, as well as backbone modifications such as retro-inverso structures have been incorporated.
(12) The angle obtained for the C alpha-D resonance was consistent with a single-stranded beta 6.3-helical model for the backbone but not with double-helical models.
(13) In the holopeptide corticotropin, the side chain-side chain effects, as reflected by the titration curves obtained from variations in the aromatic region, support the idea of an helical organization of part of the backbone even in aqueous solution.
(14) The local secondary structure was calculated from sequential and medium-range backbone NOEs with the double-iterated Kalman filter method [Altman, R. B., & Jardetzky, O.
(15) Although the (n-h) plots predict the stereochemical possibility of both right-handed and left-handed helices, nucleic acids apparently prefer right-handed conformation because of the energetics associated with the sugar-phosphate backbone and the base.
(16) And 96% of our grants go to African organisations, universities, scientists and small businesses to achieve a single goal: reduce hunger and poverty on our continent by unleashing the potential of the millions of small, family farmers who are the backbone of African agriculture and African economies.
(17) In addition the bare central backbone showed transverse striations.
(18) Misfolded models were constructed by introducing incorrect side chains onto polypeptide backbones: side chains of the alpha-helical hemerythrin were modeled on the beta-sheeted backbone of immunoglobulin VL domain, whereas those of the VL domain were similarly modeled on the hemerythrin backbone.
(19) Complete assignments were obtained for the backbone 1H, 15N and 13C resonances, using three-dimensional heteronuclear 1H NOE 1H-15N multiple-quantum coherence spectroscopy (3D-NOESY-HMQC) and three-dimensional heteronuclear total correlation 1H-15N multiple-quantum coherence spectroscopy (3D-TOCSY-HMQC) experiments on 15N-enriched HPr and an additional three-dimensional triple-resonance 1HN-15N-13C alpha correlation spectroscopy (HNCA) experiment on 13C, 15N-enriched HPr.
(20) Teh presence of the polyglycerol phosphate backbone and fatty acid was required for maximum immunosuppression of the primary immunoglobulin M response to sheep cells.
Guts
Definition:
Example Sentences:
(1) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(2) In contrast to L2 and L3 in L1 the mid gut runs down in a straight line without any looping.
(3) The goals of treatment are the restoration of normal gut peristalsis and the correction of nutritional deficiencies.
(4) Expressed per centimeter of gut length, total DAO activity was also enhanced by +141% in segment B (P less than 0.05 vs controls) and by +87% in segment C (P less than 0.01 vs controls) of resected rats.
(5) Recent studies point to the involvement of regulatory peptides in diseases of the gut and lung.
(6) "Gut closure" is an unlikely explanation for these findings.
(7) The effect of dietary fibre digestion in the human gut on its ability to alter bowel habit and impair mineral absorption has been investigated using the technique of metablic balance.
(8) ); and 3) those that multiply and produce large numbers of vegetative cells in the food, then release an active enterotoxin when they sporulate in the gut.
(9) The mRNA data of the developing gut correspond with previous protein data, which showed that the shorter Mr 210,000 polypeptide predominates during earlier developmental stages and the larger Mr 260,000 polypeptide appears later in the embryonic gut (Aufderheide, E., and P. Ekblom.
(10) The effects of intra-arterial administration of substance P upon intestinal blood flow, oxygen consumption, intestinal motor activity, and distribution of blood flow to the compartments of the gut wall were measured in anesthetized dogs.
(11) Agents that lower total plasma or LDL cholesterol in hypercholesterolaemic patients by interfering with cholesterol reabsorption from the gut (cholestyramine, cholestipol) or reduction of hepatic VLDL release (fibrates) do not appear to interfere with platelet hyperreactivity and do not change platelet-derived thromboxane formation.
(12) Females had an increased excretion of PCBs and increased accumulation in gut and gonads compared to males.
(13) The aim of the present study was to determine if dexamethasone treatment increased the rate of appearance in plasma of gut-derived glucose.
(14) The agency, which works to reduce food waste and plastic bag use, has already been gutted , with its budget reduced to £17.9m in 2014, down from £37.7m in 2011.
(15) No acute or chronic GVHD was seen in two patients, grade II (skin only) was seen in one patient, and grade IV (skin, liver, and gut) was seen in one patient.
(16) A diversity of serogroups and toxigenicity was a general finding, however, strains found in the proximal gut were also cultured from the rectum, indicating that faecal specimens would be a valid tool in investigating the role of these organisms in SIDS cases compared with healthy controls.
(17) Our results suggest that the increased Copro-IgE levels may be a specific consequence of the local immune response to food allergen stimulation in the gut mucosa.
(18) At the external wall of the host's gut, parasitic cysts of this nematode with immature stages inside were also observed.
(19) The results provide further in vivo evidence that ROI are causative agents in H liberation during reperfusion of the ischemic gut.
(20) Intravenous administration of ADS did not affect the transit, indicating the importance of the presence of ADS in the gut lumen.