(n.) The column of bones in the back which sustains and gives firmness to the frame; the spine; the vertebral or spinal column.
(n.) Anything like , or serving the purpose of, a backbone.
(n.) Firmness; moral principle; steadfastness.
Example Sentences:
(1) A method for the introduction of side chains containing isonitrile (isocyanide, functional group) on the backbone of polysaccharides and other hydroxylic polymers was developed.
(2) The chromophore of octopus rhodopsin is 11-cis retinal, linked via a protonated Schiff base to the protein backbone.
(3) An unprincipled coward with the backbone of an amoeba."
(4) The Pr(III)-induced shifts for several resolved nonexchangeable backbone proton resonances were compared with calculated shifts using the known x-ray structure.
(5) Here we present images of polydeoxyadenylate molecules aligned in parallel, with their bases lying flat on a surface of highly oriented pyrolytic graphite and with their charged phosphodiester backbones protruding upwards.
(6) These data suggest that the somnogenic actions of these lipid A analogs depend on the acylation or phosphorylation pattern and backbone structures of the molecules.
(7) The resulting family of structures has a mean backbone rmsd of 0.63 A (N, C alpha, C', O atoms), excluding the segments containing residues 45-59 and 84-88.
(8) wt polypeptide backbone, modified by an endoglycosidase F-sensitive carbohydrate moiety.
(9) The backbone dynamics of Ca(2+)-saturated recombinant Drosophila calmodulin has been studied by 15N longitudinal and transverse relaxation experiments, combined with 15N(1H) NOE measurements.
(10) A central eight-stranded beta-pleated sheet is the main feature of the polypeptide backbone folding in dihydrofolate reductase.
(11) To investigate the topochemical preference of backbone and side chains, unusual amino acids, including beta-methylphenylalanine7 or 11, beta-methyltryptophan8, as well as backbone modifications such as retro-inverso structures have been incorporated.
(12) The angle obtained for the C alpha-D resonance was consistent with a single-stranded beta 6.3-helical model for the backbone but not with double-helical models.
(13) In the holopeptide corticotropin, the side chain-side chain effects, as reflected by the titration curves obtained from variations in the aromatic region, support the idea of an helical organization of part of the backbone even in aqueous solution.
(14) The local secondary structure was calculated from sequential and medium-range backbone NOEs with the double-iterated Kalman filter method [Altman, R. B., & Jardetzky, O.
(15) Although the (n-h) plots predict the stereochemical possibility of both right-handed and left-handed helices, nucleic acids apparently prefer right-handed conformation because of the energetics associated with the sugar-phosphate backbone and the base.
(16) And 96% of our grants go to African organisations, universities, scientists and small businesses to achieve a single goal: reduce hunger and poverty on our continent by unleashing the potential of the millions of small, family farmers who are the backbone of African agriculture and African economies.
(17) In addition the bare central backbone showed transverse striations.
(18) Misfolded models were constructed by introducing incorrect side chains onto polypeptide backbones: side chains of the alpha-helical hemerythrin were modeled on the beta-sheeted backbone of immunoglobulin VL domain, whereas those of the VL domain were similarly modeled on the hemerythrin backbone.
(19) Complete assignments were obtained for the backbone 1H, 15N and 13C resonances, using three-dimensional heteronuclear 1H NOE 1H-15N multiple-quantum coherence spectroscopy (3D-NOESY-HMQC) and three-dimensional heteronuclear total correlation 1H-15N multiple-quantum coherence spectroscopy (3D-TOCSY-HMQC) experiments on 15N-enriched HPr and an additional three-dimensional triple-resonance 1HN-15N-13C alpha correlation spectroscopy (HNCA) experiment on 13C, 15N-enriched HPr.
(20) Teh presence of the polyglycerol phosphate backbone and fatty acid was required for maximum immunosuppression of the primary immunoglobulin M response to sheep cells.
Vertebra
Definition:
(n.) One of the serial segments of the spinal column.
(n.) One of the central ossicles in each joint of the arms of an ophiuran.
Example Sentences:
(1) It is concluded that during exposure to simulated microgravity early signs of osteoporosis occur in the tibial spongiosa and that changes in the spongy matter of tubular bones and vertebrae are similar and systemic.
(2) It is suggested that the Japanese may have lower trabecular bone mineral density than Caucasians but may also have a lower threshold for fracture of the vertebrae.
(3) The various changes were accompanied by a marked reduction in the overall wet weight of the vertebrae.
(4) The BMD of the 2nd to 4th lumbar vertebrae was measured and the mean density presented as g cm-2.
(5) All the vertebrae were agenetic below the thoracic segments in the other rat fetus.
(6) Neusticosaurus species are easiest separated by their number of presacral vertebrae.
(7) This was followed by a gradual density increase such that by 1 year postoperatively, in 60% of the subjects, the density of these vertebrae was higher than the preoperative level.
(8) The characteristic injuries were compression wedge-shaped fractures, multiple fractures of the vertebrae, comminuted and traumatic spondylolistheses and dislocation fractures.
(9) They make it possible to dissect, by spending minimal time and making less efforts, the vertebral canal both within several vertebrae and its nearly full length, providing a wide view of the spinal cord, rootlets, and intervertebral ganglia.
(10) The Authors describe the moniliform structure of dorsal aorta of the Cyprinus carpio L., which has successive swellings and constrictions, strictly corresponding to each vertebra.
(11) He also had multiple follicular and papillary thyroid carcinomas with a metastatic lesion in the lumbar vertebrae.
(12) In older children, there were a low vertebral signal and disappearance of the disc-vertebra borders on T1-weighted images and a high vertebral signal with a decreased and flattened disc signal on T2-weighted images.
(13) Hyperthermia was applied in the region of the vertebral column between the cervical vertebrae 5 and thoracic 2, using a ring-shaped applicator operating at a microwave frequency of 434 MHz.
(14) The authors report on their experience with 23 patients with destructive disease of the vertebrae.
(15) In 20 patients, vertebral deformities were limited to 1 or 2 mid-thoracic vertebrae, and the mean CaBI values for these 20 patients was 0.81 (0.15), equal to that for patients without any vertebral deformity.
(16) Both conditions are inherited and characterised by malformed thoracic and lumbar vertebrae.
(17) The injured vertebra is grafted through the pedicle, giving security against late collapse after device removal.
(18) The authors describe two types of pelvic obliquity--total pelvic obliquity in which the sacrum is the lowest vertebra of the lumbar curve and subtotal pelvic obliquity in which there is some compensation between L5 and the sacrum.
(19) Although anterior and posterior traumatic displacement of cervical vertebrae are commonly noted, and the devastating neurological deficits associated with these injuries have been amply defined, lateral displacement with fractures has been rarely recognized, and the clinical significance of this injury has been overlooked.
(20) The T-1 nerve root obstructs posterolateral access to the T-1 vertebra, necessitating an inferolateral approach underneath the T-1 nerve root axilla.