(v. t.) To abrade or rub off any outer covering from; as to bark one's heel.
(v. t.) To girdle. See Girdle, v. t., 3.
(v. t.) To cover or inclose with bark, or as with bark; as, to bark the roof of a hut.
(v. i.) To make a short, loud, explosive noise with the vocal organs; -- said of some animals, but especially of dogs.
(v. i.) To make a clamor; to make importunate outcries.
(n.) The short, loud, explosive sound uttered by a dog; a similar sound made by some other animals.
(n.) Alt. of Barque
Example Sentences:
(1) In platform shoes to emulate Johnson's height, and with the aid of prosthetic earlobes, Cranston becomes the 36th president: he bullies and cajoles, flatters and snarls and barks, tells dirty jokes or glows with idealism as required, and delivers the famous "Johnson treatment" to everyone from Martin Luther King to the racist Alabama governor George Wallace.
(2) The cotton root bark, when used as an abortifacient, exhibits the lowest toxicity.
(3) Cruddas, who has several BNP councillors in his Barking constituency, told MPs in the House of Commons: "What's been uncovered in the internal workings of the BNP appears to be systematic illegality in terms of data protection, bugging, money laundering, theft and the operation of the Political Parties Elections and Referendums Act 2000."
(4) The non-phenolic components of the mature stem bark were shown to be (+)-pinitol, sucrose, glucose, fructose, l(-)-pipecolic acid, trans-4-hydroxy-l(-)-pipecolic acid, alpha-alanine, arginine, aspartic acid, glutamic acid, l(-)-proline, serine, a ;steroid' alcohol and a long-chain beta-diketone.
(5) There is the sound of engines hissing and crackling, which have been mixed to seem as near to the ear as the camera was to the cars; there is a mostly unnoticeable rustle of leaves in the trees; periodically, so faintly that almost no one would register it consciously, there is the sound of a car rolling through an intersection a block or two over, off camera; a dog barks somewhere far away.
(6) As previously reported, the methanol extract from the bark of AN and the fractions of the methanol extract have protective effects for liver injury induced by carbon tetrachloride (CCl4) in rats.
(7) The root bark of S. paludosum which showed curare like activity yielded tomatidenol and another yet unidentified alkaloid responsible for the biological activity.
(8) "She sat next to me when I wrote songs, and barked any time I tried to record something, and she was with me in the studio all the time we recorded the last album ."
(9) In a letter to Hodge on Tuesday, Duncan also claimed that Hodge, the MP for Barking, had made “undoubtedly libellous assertions” about the tax affairs of the bank’s chief executive Stuart Gulliver.
(10) Aggressiveness was the most obvious symptom (71%) followed by salivation (48%), paresis and paralysis (28%) and barking (11%).
(11) For that matter, mulching with bark, grit or slate will help keep the surface roots cooler and retain moisture in hot weather.
(12) Although it had been anticipated that affordable private rents in expensive inner city areas such as Westminster would be scarce, the acute housing shortage in the capital means market rents outstrip benefit cap levels in cheaper outer London boroughs including Haringey, Waltham Forest, and Barking and Dagenham.
(13) The bill should authorize stiff fines for unruly dog behavior – to include noise violations from sustained barking and lunging – and misdemeanor criminal penalties for menacing waitstaff and patrons.
(14) Their barking drew an entertaining rebuke from Ta-Nehisi Coates to which we cannot resist linking, however: Carlson's descent from reasonably credible magazine journalist to inept race hustler is well mapped territory.
(15) The strategic locations are: Stratford, in east London, which is seen as an emerging Olympic city and centrepiece of the country's bid for the 2012 Olympics; Greenwich and Woolwich, involving new and rebuilt communities near the floundering millennium dome site; Barking, where work has already begun on a new township; Thurrock in Essex, involving a new urban development corporation with sweeping planning powers, and North Kent Thameside, between Dartford and Gravesend, which embraces Ebbsfleet.
(16) The methanol extract of the stem bark of Schumanniophyton magnificum and schumanniofoside, a chromone alkaloidal glycoside isolated from it, reduced the lethal effect of black cobra (Naja melanoleuca) venom in mice.
(17) The second case describes a seventeen year old school girl who suffered from barking coughing attacks.
(18) The expertise is only to be obtained by visiting the regions where the quinquina tree grows and finding one's way with the help of willing "cascarilleros", the Indians collecting the quinquina bark.
(19) The following month the commissioner of police, Sir Paul Stephenson, came to see me to persuade me that Nick Davies was barking up the wrong tree.
(20) The 'judge-led inquiry' that never was is shut down and investigating kidnap and torture in freedom's name will be left to a watchdog that never barks and which exonerated the spooks six years ago."
Quinine
Definition:
(n.) An alkaloid extracted from the bark of several species of cinchona (esp. Cinchona Calisaya) as a bitter white crystalline substance, C20H24N2O2. Hence, by extension (Med.), any of the salts of this alkaloid, as the acetate, chloride, sulphate, etc., employed as a febrifuge or antiperiodic. Called also quinia, quinina, etc.
Example Sentences:
(1) The influence of the hexylsalicylic acid (2) on the pharmacokinetic of the quinine (1), was studied using rabbits.
(2) Concomitant with the inhibition of K+ and Na+ transport, quinine stimulates ATP hydrolysis by 57%.
(3) those that had entered the G1 phase) expressed an increased amount of Fc gamma RII and (b) blocking the entry of activated cells into the S phase (with the ion channel blocker quinine) did not affect the Fc gamma RII induction by LPS.
(4) It was found that DI rats responded less than LE rats on the progressive-ratio schedule and that DI rats suppressed drinking as much as LE rats at each concentration of quinine used on the drinking-suppression test.
(5) Microsomal metabolites were also isolated from quinine and quinidine incubations with rabbit or guinea pig liver fractions.
(6) A nearly complete blockade of channel current was observed at 100 nM quinine and above.
(7) Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for Disease Control.
(8) Cell proliferation was equally sensitive to quinine regardless of mitogen.
(9) The responses to quinine and mefloquine or halofantrine showed no correlation with each other.
(10) The CGRP-IR levels in the rostral (gustatory) part of the insular cortex were increased significantly by strongly aversive taste stimuli such as quinine hydrochloride and conditioned taste stimuli (NaCl and sucrose) which animals had been taught to avoid.
(11) Quinidine, the stereoisomer of quinine, had no effect on either cells from the patient or normal cells.
(12) Despite the presence in the region of an important resistance of Plasmodium falciparum to chloroquine (80% specimens), one can conclude to a satisfying susceptibility of this parasite to quinine, provided posology and divided doses are respected.
(13) The clinical application of the method for routine drug monitoring and for estimating the pharmacokinetics of quinine and quinidine in man are discussed.
(14) The resistance of Plasmodium falciparum, the cause of tertian malaria, to synthetic antimalarials, together with the resistance of the vector mosquitoes to insecticides, has resulted in a resurgence in the use of quinine and a search for new antimalarial agents.
(15) all infections were sensitive to quinine plus tetracycline.
(16) Quinine applied on the intracellular side of the membrane in micromolar concentrations chopped the unitary K+ currents into bursts of brief openings.
(17) This was shown by a dye exclusion test and by mitogen stimulation after exposure and removal of quinine from the medium.
(18) These are insensitive to quinine, suggesting that they are not caused by an intracellular Ca accumulation.
(19) The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use.
(20) Whether it was Sénac or Wenckebach who first observed that quinine could change an irregular heart rhythm (atrial fibrillation) into a regular one (sinus rhythm), we are not far from their empiricism.