(n.) A carpentry obstruction, stockade, or other obstacle made in a passage in order to stop an enemy.
(n.) A fortress or fortified town, on the frontier of a country, commanding an avenue of approach.
(n.) A fence or railing to mark the limits of a place, or to keep back a crowd.
(n.) An any obstruction; anything which hinders approach or attack.
(n.) Any limit or boundary; a line of separation.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(3) The findings clearly reveal that only the Sertoli-Sertoli junctional site forms a restrictive barrier.
(4) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(5) Comparison of the 50% binding concentrations of the compounds for the various PBPs of the five strains with their antibacterial activity indicates that the different antibiotics are excluded to a greater or lesser degree by the outer membrane permeability barrier and that the exclusion is most pronounced in P. aeruginosa.
(6) Preservation of dopaminergic and H1 neurotransmission, probably within the blood barrier, is needed to allow the neuroendocrine transduction of cholinergic inputs, whereas the role of 5-HT neurotransmission remains uncertain.
(7) Their levels in urine are a useful indicator of the integrity of membrane barriers of the kidney glomerular capillary wall.
(8) The IgG index (formula: see text) corrects for the influence of serum protein abnormalities as well as a bloodbrain barrier damage and is, therefore, a better measure for the presence of an IgG elevation in CSF due to IgG synthesis, when compared with other IgG quotients commonly used.
(9) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(10) No signs of the blood-brain barrier disruption were observed.
(11) Although no anatomical 'barrier' has been described, it has been suggested that the gel mucus and epithelial phospholipids are constituents.
(12) Despite their wide dispersion, Vmax and the stereological determinations correlated strongly at 2 mo of age, confirming that Vmax is a robust indicator of the surface area of the air-blood barrier.
(13) Developmental changes are delineated, with particular reference to recent work on the ovine blood-brain barrier.
(14) Features of barrier island physiography and ecology were studied relative to selective bait deployment and site biosecurity.
(15) This study sought to determine if and why barriers to the over-the-counter purchase of syringes in the St. Louis metropolitan area might exist, given that no ordinance prohibits such a sale there.
(16) It is suggested that the intercalated disc functioned as a barrier to the freezing process.
(17) To explain some of these results a theoretical model is presented to demonstrate that while short circuiting can block the passive ionic movement, it will cause an increase in the energy consumption of the system and introduce certain important changes in the ionic barriers and e.m.fs.
(18) Our results show that paramagnetic enhancement with T1-weighted imaging adds specificity and enables rapid assessment of abnormalities of the blood-brain barrier.
(19) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(20) There was a significant correlation between the lesion index and the PD reduction, although the integrity of the resting gastric mucosal barrier remained unaltered.
Carrier
Definition:
(n.) One who, or that which, carries or conveys; a messenger.
(n.) One who is employed, or makes it his business, to carry goods for others for hire; a porter; a teamster.
(n.) That which drives or carries; as: (a) A piece which communicates to an object in a lathe the motion of the face plate; a lathe dog. (b) A spool holder or bobbin holder in a braiding machine. (c) A movable piece in magazine guns which transfers the cartridge to a position from which it can be thrust into the barrel.
Example Sentences:
(1) We have measured the antibody specificities to the two polysaccharides in sera from asymptomatic group C meningococcal carriers and vaccinated adults by a new enzyme-linked immunosorbent assay (ELISA) procedure using methylated human serum albumin for coating the group C polysaccharide onto microtiter plates.
(2) These results show that lipo-PGI2 at a very low dose would be beneficial as a treatment for relieving the clinical symptoms of chronic cerebral infarction and that lipid microspheres are a useful drug carrier for PGI2 analogue therapy.
(3) Before carrier vaccines are applied, these risks must be thoroughly evaluated case-by-case.
(4) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
(5) The IgM antibody was found at high titers in each of 70 patients with inflammatory liver disease and at a low titer in one of six patients with inactive cirrhosis; it was not found in eight carriers with normal liver histology.
(6) To get a better understanding of the different cell interactions during the immune response to a hapten-carrier complex, the effects of immunogenic or tolerogenic injections of various hapten-containing compounds on the responses induced by immunization with the same hapten coupled to protein carriers were studied.
(7) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
(8) The differentiated neuroblastoma cell possesses characteristics of an electrically excitable cell and can generate propagated potential spikes in which Ca2+ is the inward charge carrier.
(9) The latter phase of depletion was associated with a decrease in synaptosomal [3H]serotonin uptake due to a loss in the number of uptake sites with no change in the affinity of the carrier for serotonin.
(10) Direct detection of the mutation enables the identification of fragile X negative normal transmitting males and fragile X negative carrier females.
(11) They strongly suggest that the ADP-carrier comes to the close neighbourhood of the ATP synthetase on the matrix side of the inner membrane.
(12) It is thus important to know whether carriers of the AT gene have a risk of cancer or diabetes greater than comparable noncarriers.
(13) The fractional rate constants for the accumulation or disappearance of the metabolites could be determined after pharmacological blockade of catabolic enzymes or the acid metabolite carrier.
(14) The initial observation of Tn551 transition involved UV inactivation of the carrier plasmid; this would appear to be a general means of detecting transposable elements.
(15) This also implies that both tubular secretion and tubular reabsorption are susceptible to competition between similar substrates for a common carrier site.
(16) Seventeen different bacteria were used in the adherence tests; ten strains of alpha-hemolytic streptococci, five from children with infective endocarditis (IE) and five from healthy carriers, two S. aureus, two N. meningitidis, two N. gonorrhoeae and one E. coli.
(17) From this, it was suggested that a negligible amount of oestradiol was released from these compounds and that the oestradiol moiety was useful as a carrier for the nitrogen mustard moiety.
(18) The amount of formazan obtained after incubating vital cells with Meldola Blue as electron carrier was greater than that obtained with Methylene Blue, menadione, 2,6-dichloroindophenol, 1-methoxyphenazine methosulphate or phenazine methosulphate.
(19) Women who were the mothers of individuals with isolated cases of hemophilia appeared to be carriers in at least 85% of cases, suggesting that the frequency of cases due to fresh mutations is low.
(20) Three mouse models of male-limited, hybrid-type sterility are available: the sterility controlled by the T-t genetic complex, the hybrid sterility system including the Hst-1 gene, and the sterility of carriers of various chromosomal anomalies.