(n.) A carpentry obstruction, stockade, or other obstacle made in a passage in order to stop an enemy.
(n.) A fortress or fortified town, on the frontier of a country, commanding an avenue of approach.
(n.) A fence or railing to mark the limits of a place, or to keep back a crowd.
(n.) An any obstruction; anything which hinders approach or attack.
(n.) Any limit or boundary; a line of separation.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(3) The findings clearly reveal that only the Sertoli-Sertoli junctional site forms a restrictive barrier.
(4) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(5) Comparison of the 50% binding concentrations of the compounds for the various PBPs of the five strains with their antibacterial activity indicates that the different antibiotics are excluded to a greater or lesser degree by the outer membrane permeability barrier and that the exclusion is most pronounced in P. aeruginosa.
(6) Preservation of dopaminergic and H1 neurotransmission, probably within the blood barrier, is needed to allow the neuroendocrine transduction of cholinergic inputs, whereas the role of 5-HT neurotransmission remains uncertain.
(7) Their levels in urine are a useful indicator of the integrity of membrane barriers of the kidney glomerular capillary wall.
(8) The IgG index (formula: see text) corrects for the influence of serum protein abnormalities as well as a bloodbrain barrier damage and is, therefore, a better measure for the presence of an IgG elevation in CSF due to IgG synthesis, when compared with other IgG quotients commonly used.
(9) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(10) No signs of the blood-brain barrier disruption were observed.
(11) Although no anatomical 'barrier' has been described, it has been suggested that the gel mucus and epithelial phospholipids are constituents.
(12) Despite their wide dispersion, Vmax and the stereological determinations correlated strongly at 2 mo of age, confirming that Vmax is a robust indicator of the surface area of the air-blood barrier.
(13) Developmental changes are delineated, with particular reference to recent work on the ovine blood-brain barrier.
(14) Features of barrier island physiography and ecology were studied relative to selective bait deployment and site biosecurity.
(15) This study sought to determine if and why barriers to the over-the-counter purchase of syringes in the St. Louis metropolitan area might exist, given that no ordinance prohibits such a sale there.
(16) It is suggested that the intercalated disc functioned as a barrier to the freezing process.
(17) To explain some of these results a theoretical model is presented to demonstrate that while short circuiting can block the passive ionic movement, it will cause an increase in the energy consumption of the system and introduce certain important changes in the ionic barriers and e.m.fs.
(18) Our results show that paramagnetic enhancement with T1-weighted imaging adds specificity and enables rapid assessment of abnormalities of the blood-brain barrier.
(19) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(20) There was a significant correlation between the lesion index and the PD reduction, although the integrity of the resting gastric mucosal barrier remained unaltered.
Crush
Definition:
(v. t.) To press or bruise between two hard bodies; to squeeze, so as to destroy the natural shape or integrity of the parts, or to force together into a mass; as, to crush grapes.
(v. t.) To reduce to fine particles by pounding or grinding; to comminute; as, to crush quartz.
(v. t.) To overwhelm by pressure or weight; to beat or force down, as by an incumbent weight.
(v. t.) To oppress or burden grievously.
(v. t.) To overcome completely; to subdue totally.
(v. i.) To be or become broken down or in, or pressed into a smaller compass, by external weight or force; as, an eggshell crushes easily.
(n.) A violent collision or compression; a crash; destruction; ruin.
(n.) Violent pressure, as of a crowd; a crowd which produced uncomfortable pressure; as, a crush at a peception.
Example Sentences:
(1) The number of axons displaying peptide-like immunoreactivity within the optic nerve, retinal or cerebral to the crush, and within the optic chiasm gradually decreased after 2-3 months.
(2) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(3) Reality set in once you got home to your parents and the regular neighborhood kids, and your thoughts turned to new notebooks for the school year and whether you got prettier while you were away and whether your crushes were going to notice.
(4) The wide variation in potency explains the variation found in absolute bioavailability, and the increase in release rate when the pellets are crushed explains the differences seen in peak plasma times, since the pellets will be chewed to varying degrees by the horse.
(5) In case 2, a 26-year-old man sustained an open total dislocation of the talus with a severe crush wound and impaired circulation to the foot.
(6) "Everyone has been blasted by anonymous figures who crushed the economy.
(7) The main objective of these experiments was to develop and characterize a new experimental model of venous thrombosis, and determine whether a combination of vascular wall damage (crushing with hemostat clamps) and prolonged stasis produced more reproducible clots than prolonged stasis per se.
(8) Despite a glorious career, her Olympic history had been one of crushing disappointment.
(9) In one group of rats, the RGC proteins were labeled 1 week after crushing.
(10) In adrenergic axons NA, DBH-IR and TH-IR accumulated with time after crushing the nerve as described earlier with biochemical techniques.
(11) This is the first reported case, to the best of my knowledge, of disk neovascularization occurring after intravenously injected, crushed, unfiltered, methylphenidate HCl tablets.
(12) An epidemic of abuse with "T's and blues" began in the late 1970's in which pentazocine-Talwin tablets ("T")--and the antihistamine tripelennamine (known as blues) were crushed, dissolved together, filtered, and injected intravenously.
(13) Labeled axons were first detected in the segment of optic nerve lying distal to the crush site 1 week after injury and had extended as far as 2.3 mm beyond the crush site by 60 days postinjury, growing at a rate similar to that at which the collateral branches of developing ganglion cell axons extend into their targets.
(14) On 21 August 1968, armies of five Warsaw Pact countries – the Soviet Union, Poland, Hungary, Bulgaria and East Germany – invaded Czechoslovakia to crush democratic reforms known as the Prague spring.
(15) Freeze-dried crushed cortical bone allografts were implanted into widemouthed three-wall, two-wall, one-wall, combination, and furcation defects.
(16) Previous work from our laboratory had shown that goldfish retinal fragments explanted onto a polylysine substratum 1 to 2 weeks following optic nerve crush exhibit a striking clockwise pattern of neuritic outgrowth.
(17) Thus did Dominic Cummings, former special adviser to Michael Gove , deliver to his prime minister what is, in certain Tory circles, the most crushing of insults.
(18) Isis recently threatened to kill American hostages to avenge the crushing airstrikes in Iraq against militants advancing on Mount Sinjar and the Kurdish capital of Irbil.
(19) Addictive onion consumption was prevented by mixing chopped or crushed onions in a total balanced ration.
(20) On a turnout of 50.78%, Labour's shellshocked candidate Imran Hussain was crushed by a 36.59% swing from Labour to Respect that saw Galloway take the seat with a majority of 10,140.