(n.) A carpentry obstruction, stockade, or other obstacle made in a passage in order to stop an enemy.
(n.) A fortress or fortified town, on the frontier of a country, commanding an avenue of approach.
(n.) A fence or railing to mark the limits of a place, or to keep back a crowd.
(n.) An any obstruction; anything which hinders approach or attack.
(n.) Any limit or boundary; a line of separation.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(3) The findings clearly reveal that only the Sertoli-Sertoli junctional site forms a restrictive barrier.
(4) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(5) Comparison of the 50% binding concentrations of the compounds for the various PBPs of the five strains with their antibacterial activity indicates that the different antibiotics are excluded to a greater or lesser degree by the outer membrane permeability barrier and that the exclusion is most pronounced in P. aeruginosa.
(6) Preservation of dopaminergic and H1 neurotransmission, probably within the blood barrier, is needed to allow the neuroendocrine transduction of cholinergic inputs, whereas the role of 5-HT neurotransmission remains uncertain.
(7) Their levels in urine are a useful indicator of the integrity of membrane barriers of the kidney glomerular capillary wall.
(8) The IgG index (formula: see text) corrects for the influence of serum protein abnormalities as well as a bloodbrain barrier damage and is, therefore, a better measure for the presence of an IgG elevation in CSF due to IgG synthesis, when compared with other IgG quotients commonly used.
(9) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(10) No signs of the blood-brain barrier disruption were observed.
(11) Although no anatomical 'barrier' has been described, it has been suggested that the gel mucus and epithelial phospholipids are constituents.
(12) Despite their wide dispersion, Vmax and the stereological determinations correlated strongly at 2 mo of age, confirming that Vmax is a robust indicator of the surface area of the air-blood barrier.
(13) Developmental changes are delineated, with particular reference to recent work on the ovine blood-brain barrier.
(14) Features of barrier island physiography and ecology were studied relative to selective bait deployment and site biosecurity.
(15) This study sought to determine if and why barriers to the over-the-counter purchase of syringes in the St. Louis metropolitan area might exist, given that no ordinance prohibits such a sale there.
(16) It is suggested that the intercalated disc functioned as a barrier to the freezing process.
(17) To explain some of these results a theoretical model is presented to demonstrate that while short circuiting can block the passive ionic movement, it will cause an increase in the energy consumption of the system and introduce certain important changes in the ionic barriers and e.m.fs.
(18) Our results show that paramagnetic enhancement with T1-weighted imaging adds specificity and enables rapid assessment of abnormalities of the blood-brain barrier.
(19) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(20) There was a significant correlation between the lesion index and the PD reduction, although the integrity of the resting gastric mucosal barrier remained unaltered.
Hurdle
Definition:
(n.) A movable frame of wattled twigs, osiers, or withes and stakes, or sometimes of iron, used for inclosing land, for folding sheep and cattle, for gates, etc.; also, in fortification, used as revetments, and for other purposes.
(n.) In England, a sled or crate on which criminals were formerly drawn to the place of execution.
(n.) An artificial barrier, variously constructed, over which men or horses leap in a race.
(v. t.) To hedge, cover, make, or inclose with hurdles.
Example Sentences:
(1) Arsenal’s 10 men fall at the first hurdle against Dinamo Zagreb Read more This win, even against such feeble opponents, was celebrated, with the locals chorusing their manager’s name amid a wave of relief given so much of the team’s domestic campaign to date has been dismal.
(2) The idea was to create a simple set of standards that everyone can relate to, a low hurdle that every humanitarian organisation should be able to leap over.” As organisations grow, they can aspire to use more technical standards that more established NGOs might already be working with.
(3) The physician who cares for adolescents has the responsibility of helping parenting teens to find needed support so that they will be able to overcome this significant hurdle.
(4) When I had that keyhole surgery, I thought: ‘Maybe, if I come back, it won’t be to that top level.’ But with the support I have been getting from my coach, family and friends, I think that really motivated me to come back strong.” Kenya is more famed for its distance runners and steeplechasers than its hurdlers, but the country was left celebrating a surprise gold medal in the 400m hurdles when Nicholas Bett powered home from lane nine to smash his personal best to win in 47.79sec.
(5) Cards pile on the runs, and here comes Hurdle to get Burnett, about three batters too late.
(6) However, despite repeated questions from reporters, Earnest did not rule out Obama approving fast-track without TAA if that combination somehow made it through procedural hurdles in the Senate.
(7) The government is thought to believe that a major hurdle in attracting participants was the fact that it was seen as a service for the lowest socioeconomic groups.
(8) Only a handful of opposition MPs have hurdled the obstacles to win election.
(9) While some predicted their team would once again choke at the final hurdle, the chancellor had faith the “system” would be fully endorsed.
(10) Finding the funds to invest in durable and improved sanitation remains a major hurdle.
(11) Her celebrated experiment with a pseudonym as a demonstration of the hurdles facing unknown writers being just one example.
(12) I just thought it was a little beyond me this year.” On those hazy days in London Ennis-Hill had blown away the opposition with a nerveless and spectacularly quick hurdles on the opening morning of competition that left her cruising to victory.
(13) The great hurdle in all space missions is the cost of launch and the weight of fuel.
(14) However, if what happened with Indiegogo is any indication, the project will likely face more legal hurdles in the future.
(15) Carmarthen ham, an air-dried ham similar to serrano, which has been produced to a recipe by five generations of the same Welsh family, is likely to be the next UK food application to clear the regulatory hurdles.
(16) Some people believe that it just works but the reality is that the online buyer-seller relationship can falter at any one of a number of hurdles.
(17) Medical barriers to family planning (FP) are identified as contraindications, eligibility, process hurdles, the provider of contraception, provider bias, and regulation.
(18) Extinction was conducted in the runway, and subsequently the animals were tested for hurdle-jump escape from the frustrating goal box.
(19) Then they let me go in.” It wasn’t a straightforward process, he explains: his first go was on his own, on videotape; having negotiated that hurdle, he read for casting director Ellen Chenoweth; only then did he get to audition – twice – in front of the Coens themselves.
(20) The pension scheme is regarded as a hurdle to a rescue deal.