(a.) Reddish brown; of the color of a chestnut; -- applied to the color of horses.
(n.) An inlet of the sea, usually smaller than a gulf, but of the same general character.
(n.) A small body of water set off from the main body; as a compartment containing water for a wheel; the portion of a canal just outside of the gates of a lock, etc.
(n.) A recess or indentation shaped like a bay.
(n.) A principal compartment of the walls, roof, or other part of a building, or of the whole building, as marked off by the buttresses, vaulting, mullions of a window, etc.; one of the main divisions of any structure, as the part of a bridge between two piers.
(n.) A compartment in a barn, for depositing hay, or grain in the stalks.
(n.) A kind of mahogany obtained from Campeachy Bay.
(n.) A berry, particularly of the laurel.
(n.) The laurel tree (Laurus nobilis). Hence, in the plural, an honorary garland or crown bestowed as a prize for victory or excellence, anciently made or consisting of branches of the laurel.
(n.) A tract covered with bay trees.
(v. i.) To bark, as a dog with a deep voice does, at his game.
(v. t.) To bark at; hence, to follow with barking; to bring or drive to bay; as, to bay the bear.
(v. i.) Deep-toned, prolonged barking.
(v. i.) A state of being obliged to face an antagonist or a difficulty, when escape has become impossible.
(v. t.) To bathe.
(n.) A bank or dam to keep back water.
(v. t.) To dam, as water; -- with up or back.
Example Sentences:
(1) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(2) The biphasic response to (-)-(S)-Bay K 8644 and (+)-(S)-202-791 suggests that the properties of Ca++ channel activation and antagonism may reside within a single 1,4-dihydropyridine molecule.
(3) The Ca2+ agonist Bay K 8644 (1 microM) potentiated the effects of elevated K+ on both ChAT and TOH.
(4) BAY 19139, 1-(4-chlorophenoxy)-1-(1-imidazolyl)-3,3-dimethyl-2-butanol is a new imidazolyl derivative of antifungal agent.
(5) The effects of the dihydropyridine calcium channel agonist Bay K 8644 on indo-1-loaded Jurkat human leukemia T lymphocytes was assessed by flow cytometry.
(6) While visitors amble freely around the newly refurbished inside – the Pierhead is sure and steadfast in its role outside as the drastic red building, emblazoning the landscape of Cardiff Bay in all its regal beauty.
(7) These mutants have been used to test for the presence of their required metabolites in natural seawater samples from the Gulf of Mexico and adjacent bays.
(8) Now remarried, and a father, he is standing for Plaid Cymru, again in the Cardiff Bay seat.
(9) The administration is also attacked for endangering America with its proposals to dismantle the prison at Guantánamo Bay.
(10) These observations are consistent with the high sensitivity of the newborn mouse lung towards the tumorigenic effects of bay region diolepoxides.
(11) At doses of 1, 5 and 10 mg kg-1 Bay K 8644 antagonized the anaesthetic effects of pentobarbitone.
(12) We knew how good they were at keeping the ball and moving it around and we knew we would have to work hard to keep them at bay.
(13) San Francisco Tenderloin map They could potentially gentrify this gritty, 50-block swath of downtown into condos, lofts, hipster bars, organic cafes and yoga studios, as has happened in other parts of San Francisco and the Bay area.
(14) When tested on rat atrium, SNP by itself had no effect on basal inotropy or the increase in inotropy induced by (-)-S-BAY K 8644.
(15) Subjects were 862 nonsmoking coronary patients in the San Francisco Bay Area, randomized in 1978 to receive, over 4.5 years, cardiac counseling or cardiac counseling plus type A behavioral counseling.
(16) And so, through Trove’s archived newspapers, I’ve found Harry – the mission boy who saw the Japanese at Caledon Bay imprison women, girls and old men in the trepang smokehouse, before raping the women in the bush.
(17) AHH-active PCB congeners (intrinsic effects) and PCBs in general (extrinsic effects) appeared to be the only contaminants at the concentrations measured in eggs, capable of producing the effects that were observed at Green Bay.
(18) Every time we have a negotiation, the bidding process (for the project) slows and postpones things.” Water quality has become a hot-button issue as the Olympics draw closer with little sign of progress in cleaning up the fetid bay, as well as the lagoon system in western Rio that hugs the sites of the Olympic park, the very heart of the games.
(19) Alternans of both action potential shape and APD was suppressed by nisoldipine (2 X 10(-6) M) and attenuated by Bay K 8644 (3 X 10(-8) M).
(20) The last American soldier held captive by the Afghan Taliban has been released, after the US government agreed to free five Afghan detainees from the Guantánamo Bay prison in Cuba to the custody of the Qatari government, US officials said.
Channel
Definition:
(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.