What's the difference between benign and malignancy?

Benign


Definition:

  • (a.) Of a kind or gentle disposition; gracious; generous; favorable; benignant.
  • (a.) Exhibiting or manifesting kindness, gentleness, favor, etc.; mild; kindly; salutary; wholesome.
  • (a.) Of a mild type or character; as, a benign disease.

Example Sentences:

  • (1) This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign course.
  • (2) Weddellite calcification was associated with benign lesions in 16 cases, but incidental atypical lobular hyperplasia and lobular carcinoma in situ were present, each in one case.
  • (3) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
  • (4) The vulvar white keratotic lesions which have been subjected to histological examination in Himeji National Hospital (1973-1987) included 13 cases in benign dermatoses, 4 cases in vulvar epithelial hyperplasia, 3 cases in lichen sclerosus, and 3 cases in lichen sclerosus with foci of epithelial hyperplasia.
  • (5) Such complications as intracerebral haematoma or meningeal haemorrhage may occur during the usually benign course of the disease.
  • (6) Aneurysmal bone cyst is an uncommon benign lesion that rarely presents in the craniofacial region.
  • (7) Benign and malignant epithelial and soft tissue tumors of the skin were usually negatively stained with MoAb HMSA-2.
  • (8) HCT were classified by light microscopy as benign (n = 22), intermediate (n = 30), and malignant (n = 13).
  • (9) Four cases of benign lymphoid hyperplasia (BLH) of the duodenal bulb are reported.
  • (10) However, in benign prostatic hypertrophy (BPH) cases, a high false positive rate of 41% was observed in Americans.
  • (11) One week after initiation is 1-2 months before the appearance of benign papillomas that harbor activated Ha-ras oncogenes when the initiated mice are promoted with the tumor promoter phorbol 12-myristate 13-acetate.
  • (12) Gangliogliomas are rare benign tumors of the central nervous system containing neoplastic ganglion and low grade glial cells.
  • (13) It is important to be aware of the histological characteristics of this essentially benign condition so that unnecessary radical therapies can be avoided.
  • (14) No malignant tumour failed to be diagnosed (100% reliable), the anatomopathological examination of specimens in benign conditions was never wrong (100% reliable).
  • (15) Positive staining was present in cells in almost all of the benign and fibro-histiocytic lesions but was reduced in the malignant group.
  • (16) In this paper, 5 patients with benign tumor (3 tubular adenoma, 1 leiomyoma and 1 fibroma) and 35 pseudotumor (26 cholesterol polyps and 9 inflammatory polyps) of the gallbladder are presented.
  • (17) Because of the small number of cases (7), however, we are not able to state whether it is possible to distinguish between benign and malignant tumors in all cases.
  • (18) This postoperative surveillance was aimed at discovering benign or malignant neoplastic growth within the remaining large bowel.
  • (19) However, despite extreme neutropenia, infection is rare in chronic benign neutropenia patients.
  • (20) In contrast, there was only a 5% incidence of malignant neoplasia and a 29% incidence of benign neoplasia in the respiratory region.

Malignancy


Definition:

  • (n.) The state or quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart.
  • (n.) Unfavorableness; evil nature.
  • (n.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.
  • (n.) The state of being a malignant.

Example Sentences:

  • (1) In contrast to previous reports, these tumours were more malignant than osteosarcomas and showed a five-year survival rate of only 4-2 per cent.
  • (2) Oral administration in domestic cats causes malignant hepatomas and tumors of the esophagus and kidney.
  • (3) In view of reports of the reduction of telomeric repeats in human malignant tumors, we measured the lengths of telomeric repeats in 55 primary neuroblastomas.
  • (4) The frequency of gastric malignancies in the families of the women with gastric polyps was higher than in the controls and in men, 6.2, 3.1 and 2.4 percent, respectively (p less than 0.05, and p less than 0.025).
  • (5) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
  • (6) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
  • (7) Normal cultured human epidermal melanocytes and melanoma cells derived from three different malignant melanomas were examined for synthesis of extracellular matrix components before and after treatment for one day with interferon-gamma, tumor necrosis factor-alpha, or both.
  • (8) The presence of these markers has facilitated the identification and characterization of the mononuclear cells in a number of animal and human lymphoid malignancies.
  • (9) Benign and malignant epithelial and soft tissue tumors of the skin were usually negatively stained with MoAb HMSA-2.
  • (10) HCT were classified by light microscopy as benign (n = 22), intermediate (n = 30), and malignant (n = 13).
  • (11) This case is unusual in that it demonstrated no malignant epithelium beyond that of a borderline tumor, but met the criteria of malignancy because of its invasiveness and metastasis.
  • (12) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
  • (13) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
  • (14) In the control group it was 18% and in other malignancies 20%.
  • (15) Total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and the percentage distribution of LDH isoenzymes were determined in 127 patients with malignant diseases.
  • (16) In our opinion, a carcinologically "malignant" metastatic myxoma remains a questionable pathological entity.
  • (17) Hexokinase, phoshofructokinase, and aldolase appear to be rate-limiting in normal cervix epithelium; however, since the increase in activity of the first two in cancers was least of all the glycolytic enzymes, redundant enzyme synthesis probably occurs in the malignant cell for the enzymes catalysing reversible reactions.
  • (18) The flow cytometric measured DNA content (i.e., DNA index), S-fractions, and histopathologic malignancy grades were studied for ninety uterine cervical squamous cell carcinomas using tissue biopsies taken prior to radiotherapy.
  • (19) Changes in the plasma lipid composition are observed in patients and animals with malignancy and certain other diseases that are consistent with peroxidation of plasma lipoprotein lipids.
  • (20) It was difficult to assess the diagnosis of malignant mesothelioma on isolated differentiated mesothelial cells in pleural fluids or biopsies.