(n.) A volatile, very inflammable liquid, C6H6, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation. The name is sometimes applied also to the impure commercial product or benzole, and also, but rarely, to a similar mixed product of petroleum.
Example Sentences:
(1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(2) Essential parameters of hepatic functioning in 84 labourers, whose exposition to benzene is differing in assimilation as well as length of time is discussed.--45 persons from the same county without contact to benzene or hepatotoxic agents served as control-group.
(3) In the liver, the major site of benzene metabolism, benzene is converted by a cytochrome P-450-mediated pathway to phenol, the major metabolite, and the secondary metabolites, hydroquinone and catechol.
(4) The significance of the present findings on the mutual suppression of metabolism between benzene and toluene is discussed in relation to solvent toxicology and biological monitoring of exposure to the solvents.
(5) Service station attendants' exposure to benzene, based on 85 TWA results at 7 stations, were well below 1 ppm except one exposure of 2.08 ppm.
(6) For cases where background contamination could not be adequately controlled, the assay was modified for the quantitative determination of labelled benzenes six mass units heavier than natural benzene (benzene-d6 or benzene-13C6).
(7) We have investigated the whole-body dermal penetration of styrene, xylene, toluene, perchloroethylene, benzene, halothane, hexane, and isoflurane in rats and compared the permeability constants with available human studies on vapor penetration.
(8) Numerical and structural chromosome changes in bone marrow cells have been described in subjects with benzene haemopathy.
(9) On the other hand, Sudan III pretreatment suppressed benzene-induced CA at all periods after the benzene injection.
(10) Benzene is the only chemical agent for which strong evidence of leukaemogenesis exists.
(11) 14C-Methylthio-labelled 2-methylthio-4-ethylamino-6-tert-butylamino-sym-triazine (terbutryn), pentachlorothioanisole (PCTA), and 1,4-bis(methylthio)tetrachloro-benzene (bis-MTTCB) and their methylthio-oxidation congeners were reacted with glutathione (GSH) in the presence and absence of immobilized liver microsomal enzymes.
(12) The drug is extracted from buffered plasma at pH 9.0 with benzen.
(13) Laser photolysis techniques have been used to characterize the reactivity of triplet state lipoidal benzophenone derivatives toward fatty acids and glycerides in benzene solution.
(14) In experiments in vitro, neither benzene, toluene nor xylene changed the number of sister-chromatid exchanges (SCEs) or the number of chromosomal aberrations in human lymphocytes.
(15) The compound is extracted from aqueous solution with benzene and cleaned up by liquid chromatography.
(16) In pursuing the study on pyridodiazepinone derivatives, in order to verify the variation of biological activity induced by replacement of the heteroaromatic with an aromatic nucleus and by the introduction of chlorine on the benzene ring, a series of 1-[(dialkylamino)alkyl]-4-phenyl-1,3-dihydro-2H-1,4-benzodiazepin- 2-ones and of 7-chloro-analogues were prepared.
(17) Benzene toluene, styrene, 1,1,1-trichloroethylene, and tetrachloroethylene are taken as examples of solvents showing various toxicokinetic properties.
(18) DAS protected the anion exchange system not only against inhibition by DNFB but also by m-isothiocyanato benzene sulfonic acid.
(19) The m-xylene-adapted microorganisms in the aquifer column degraded toluene, benzaldehyde, benzoate, m-toluylaldehyde, m-toluate, m-cresol, p-cresol, and p-hydroxybenzoate but were unable to metabolize benzene, naphthalene, methylcyclohexane, and 1,3-dimethylcyclohexane.
(20) Anticonvulsant activity and toxicity of 20 arylsuccinimides were quantitatively correlated with the hydrophobic, electronic and steric parameters of the substituents in the benzene ring and at the nitrogen atom.
Biphenyl
Definition:
Example Sentences:
(1) Of 15 organochlorine compounds analyzed, trace amounts mainly of p,p-DDE and polychlorinated biphenyls (PCBs) were detected, but could not be quantitated.
(2) Mutagenicity of MC was increased when homogenates from MC-treated hamsters were used as a source of activating enzymes, and this mutagenicity could be correlated with increased biphenyl 2-hydroxylase activity.
(3) We have investigated the metabolism of polychlorinated biphenyls and endogenous steroids by the major phenobarbital (PB)-inducible hepatic cytochromes P450 in dogs and rats, PBD-2 and PB-B, respectively.
(4) Studies of structure-transacylation relationships for a series of acylhydroxamic acids of chlorinated biphenyl ethers and their related compounds by rat liver N-arylacylhydroxamic acid-dependent N-acyltransferase (AHNAT) are described.
(5) There was an 84% decrease in the yield of microsomal protein, a 64% decrease in cytochrome P-450 content per mg of microsomal protein, and a 36% decrease in the biphenyl 4-hydroxylase specific activity in human cadaver liver that was a few hours old.
(6) Distribution of polychlorinated biphenyls (PCB) in sewage wastes at a municipal sewage treatment plant was studied, showing that the great bulk of PCBs entering such a treatment plant become adsorbed onto the grit chamber solids and the sludge that is passed from the anaerobic digesters.
(7) Certain metabolites of polychlorinated biphenyls (PCBs) are retained in the Clara cells and in the airway lumen of rodent lung due to their interaction with a secretory 13-kDa protein.
(8) The degradation of 3- and 4-HBs by these strains is therefore analogous to the metabolism of biphenyl, 2-HB, and naphthalene in the requirement for 2,3-catechol formation.
(9) They appear to be a dimer, trimer and tetramer in which tyrosine units are linked by biphenyl bonds.
(10) The influence of serum lipids and proteins on partitioning of individual polychlorinated biphenyl (PCB) congener peaks between human serum and adipose tissue lipid was assessed using regression analysis.
(11) Regions were ranked according to the mean concentration of 43 toxic substances (pesticides, polychlorinated biphenyls, semi-volatiles, and volatiles) in human adipose tissue and environmental media (sediment, fish tissue, and groundwater).
(12) Polychlorinated biphenyls are stable, lipophilic industrial compounds that are present in residue levels in human tissue, wildlife, and freshwater sediment.
(13) On the basis of a closeness criterion of 10 (deltaRI = RIa - RIb = 10), those combinations of three or fewer liquid phases which could distinguish between nearly all possible pairs of chlorinated biphenyls were selected.
(14) The toxic effects of the polychlorinated biphenyls upon plasma testosterone levels, the blood coagulation system, the gross- and micropathological changes as well as the extent and differences in their distribution and accumulation were studied.
(15) The efficacy of sulfuric acid cleanup and KOH-ethanol hydrolysis confirmation was studied for 22 organochlorine pesticides and 2 polychlorinated biphenyls (PCBs).
(16) A comparison is made of supercritical fluid extraction (SFE) with two other techniques widely used for the extraction of polychlorinated biphenyls (PCBs) and organochlorine pesticides in soil.
(17) Contamination by industrial chemicals such as polychlorinated biphenyls and polybrominated biphenyls; heavy metals such as lead, cadmium, and mercury; and pesticides such as dieldrin and chlordane exemplify the problem in feeds and the resulting problem of tissue residues in human foods.
(18) The effect of polychlorinated biphenyls, gamma-hexachlorocyclohexane and the effect of a combination of these substances on the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase were investigated.
(19) Experimental studies have demonstrated that certain types of commercially produced polychlorinated biphenyls (PCBs) are carcinogenic.
(20) The livers, lungs, and small intestines of untreated rabbits and the livers of control rats were stored intact, or as microsomal suspensions, under liquid nitrogen at -196 degrees C. Aniline hydroxylase, aminopyrine demethylase, benzpyrene hydroxylase, biphenyl hydroxylase, NADPH-cytochrome c reductase, UDP-glucuronyltransferase activities, the microsomal content of cytochrome P-450, and the aniline- and benzphetamine-induced spectral changes were compared in fresh and stored preparations.