(1) Deuterium-labeled aspirin (2-acetoxy[3,4,5,6-2H4]benzoic acid) was synthesized from salicylic acid by catalytic exchange and subsequent acetylation.
(2) For one patient who reacted to the placebo and one who reacted to benzoic acid, the challenges were repeated with positive results in both instances.
(3) During a five-year-period (1985-1989) 420,000 newborns in Lower Saxony, FRG, were screened for biotinidase deficiency using biotinyl-para-amino-benzoic-acid as substrate.
(4) The major urinary metabolite was hippuric acid (c. 66% of the dose), with benzoic acid (2%) and benzylmercapturic acid (1%) also present.
(5) An extensive set of computed molecular properties, both steric and electronic, have been calculated using molecular orbital and empirical methods for benzoic acid (1) and a congeneric series of substituted benzoic acids, i.e.
(6) The bovine liver monoamine oxidase (EC 1.4.3.4) was found to be inactivated by various well-known sulfhydryl reagents like p-mercuribenzoate, methylmercuric iodide and 5,5'-dithiobis-(2-nitro benzoic acid).
(7) Urine was collected from an individual at various times of gestation, and the hCG fraction was concentrated by benzoic acid and ethanol precipitation.
(8) It has been found that there are concentrative antimicrobiological ingredients in the liquid such as phenols, benzoic acids, fatty acids, and so on.
(9) The triazene derivative 1-p-(3-methyltriazeno)benzoic acid potassium salt (MTBA) shows pharmacological properties similar to those of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC, trade name dacarbazine), which is known to induce antigenic modulation in tumor cells (xenogenization) and is currently used in cancer therapy.
(10) The present investigation was undertaken to gain insight into the factors governing diffusion of a series of monosubstituted benzoic acids across ethylene-vinyl acetate copolymers.
(11) When the luminal solution was well-stirred, the absorption of benzoic acid in the lower pH region significantly increased, resulting in the disappearance of the shift of pH-absorption curve for benzoic acid.
(12) Synergism between benzoic and sorbic acid was pH dependent.
(13) Skin partition coefficients were measured over a range of benzoic acid concentrations in both saline and distilled water.
(14) In addition, intracellular pH, as estimated by the measurement of the equilibrium distribution of benzoic acid, did not show any significant alteration in cells incubated in the presence of bicarbonate buffer and in low extracellular Na+.
(15) The compound (E)-4-2-(5,6,7,8)tetrahydro-5,5,8,8-tetramethyl-2-naphtalenyl)prop enyl benzoic acid (Ro 1374-10) was approximately 2-3 orders of magnitude more potent than all-trans-retinoic acid in inhibiting breast carcinoma cell proliferation while the compound SRI-6409-40, which differs from Ro 1374-10 only by the position of a methyl group, was 50-fold more potent than Ro 1374-10.
(16) Asthma and rhinitis are the main hypersensitivity symptoms in the respiratory tract, and azo dyes, benzoic acid, and sulfitic food additives are the most common causative agents.
(17) The sulphonamide group is split off and the benzoic acid thus formed is subjected to a gas chromatographic analysis.
(18) Their structure-activity relationships are very similar to those of other retinoidal benzoic acids which are generally represented by 4 and named retinobenzoic acids.
(19) This study confirms the immaturity of the benzoic acid detoxification process in premature newborns.
(20) A polyamide-based solid-phase support containing an acid-stable p-(oxymethyl)benzoic acid handle to anchor the COOH-terminal amino acid was utilized in the production of synthetic peptides analogous to amino acid sequences 503-532 from the human immunodeficiency virus (HIV) envelope glycoprotein.
Benzoin
Definition:
(n.) A resinous substance, dry and brittle, obtained from the Styrax benzoin, a tree of Sumatra, Java, etc., having a fragrant odor, and slightly aromatic taste. It is used in the preparation of benzoic acid, in medicine, and as a perfume.
(n.) A white crystalline substance, C14H12O2, obtained from benzoic aldehyde and some other sources.
(n.) The spicebush (Lindera benzoin).
Example Sentences:
(1) We report on a patient who developed necrotizing contact dermatitis after a single topical application of tincture of benzoin and a pressure bandage following enucleation of an eye.
(2) The patient was a 17-year-old female Indian who had received some 3 to 8 cc of a 20 percent mixture of podophyllum resin in compound tincture of benzoin (approximately equal to 0.4 gm of podophylotoxin) as an application to her vulvar condylomata.
(3) Isopropyl alcohol, Betadine, benzoin, and Cidex do not damage the catheter.
(4) The genetic toxicity of 12 chemicals with sufficient data is discussed in detail: benzoin, caffeine caprolactam, ethanol, halothane, hycanthone methanesulfonate, malathion, maleic hydrazide, methotrexate, 1-naphthylamine, 4-nitro-o-phenylenediamine, and p-phenylenediamine.
(5) The results showed that dressings containing tincture of benzoin adversely affected wound healing in children.
(6) A high-performance liquid chromatographic method is described for the assay of angiotensin-converting enzyme in human serum and for the separation of angiotensins and their analogues after pre-column fluorescence derivatization with benzoin.
(7) The method has been applied to 2 benzoin preparations and the results were compared with those from the British Pharmacopoeia method.
(8) This ability is due to benzaldehyde lyase, a new type of enzyme that irreversibly cleaves the acyloin linkage of benzoin, producing two molecules of benzaldehyde.
(9) The method is based on the quantification of the enzymatically produced angiotensin I. Angiotensin I liberated from a synthetic substrate (tridecapeptide of human angiotensinogen) and [Val5]-angiotensin I as an internal standard are converted into fluorescent derivatives by reaction with benzoin.
(10) One such scheme utilizes a selective reaction of benzoin with the guanidine moiety to derivatize arginine residues occurring in a peptide.
(11) It was therefore concluded that caprolactam and benzoin are not clastogenic in the mouse micronucleus test.
(12) The presence of hydrophobic solvent in the reaction medium provides more favourable conditions for benzoin condensation proceeding.
(13) Two methods of podophyllin application, namely hospital-application (regimen A) and self-application (regimen B) of 25% podophyllin in tincture of benzoin compound for the treatment of penile condylomata were compared.
(14) The percutaneous absorption of the fragrances benzyl acetate and five other benzyl derivatives (benzyl alcohol, benzyl benzoate, benzamide, benzoin and benzophenone) was determined in vivo in monkeys.
(15) Benzoin and caprolactam were examined for their capability of inducing alkaline DNA fragmentation in mouse and rat liver DNA after treatment in vivo.
(16) The benzoin reaction, described by Guillain, Laroche and Lechelle (1920) was probably the first test evaluating local (intrathecal) immunity in inflammatory diseases of the nervous system.
(17) The monomer mixture consists of equal proportions by volume of acrylonitrile, dimethyl acrylamide and methyl methacrylate, and may be polymerized by exposure to ultraviolet light in the presence of benzoin methyl ether as catalyst.
(18) A summary is presented of the published literature on the genetic toxicology of the two rodent non-carcinogens benzoin and caprolactam.
(19) The peptides are automatically converted into fluorescent derivatives with benzoin, a fluorogenic reagent for guanidino compounds, after separation on a reversed-phase column (TSKgel ODS-120T) and detection in an ultraviolet absorption detector.
(20) Both non-carcinogenic compounds, benzoin and caprolactam, exhibited no activity.