(1) P1,P2-Bidentate Cr(H2O)4PPS and Co(NH3)4PPS (prepared from PPS) were both found to be substrates for PPase.
(2) The beta, gamma-bidentate of chromium(III)ATP (Kd = 8 microM) had a higher than the alpha, beta, gamma-tridentate of chromium(III)ATP (Kd = 44 microM) or the cobalt tetramine complex of ATP (Kd = 500 microM).
(3) Hexadentate ligands would be preferable to bidentate compounds but no suitable compounds are available.
(4) PPase was unable to catalyze the hydrolysis of Mg(H2O)4PNP and P1,P2-bidentate Co(NH3)4PNP under conditions that resulted in rapid hydrolysis of the corresponding metal-PPi complexes.
(5) It is proposed that all of the anions behave as bidentate ligands, with coordination to the iron through both the carboxylate and proximal groups, and the carboxyl group serves as a bridge between the iron and a positively charged group on the protein.
(6) Paramagnetic effects of beta,gamma-bidentate Cr3+ATP on the longitudinal relaxation rates of protons of the peptide provided a set of distances to the side chains of five residues, which allowed the location of the bound Cr3+ atom to be uniquely defined.
(7) It is most likely that one C126 per subunit provides high-avidity bidentate ligation to Hg(II), but it remains possible that C82 may be a secondary Hg(II) ligand (e.g., in a tetracoordinate thiol ligation array).
(8) Mass spectrometry and 1H-NMR indicated that the (d,l-trans-1,2-diaminocyclohexane)methionineplatinum(II) complexes that formed in RPMI-1640 medium consisted of approximately 60% of the bidentate mono-methionine complex coordinated to platinum at the sulfur and alpha-amino positions and 40% of the bis-methionine complex, presumably coordinated at the sulfurs.
(9) Spectroscopic and other evidence indicated that the sugar anions bind monodentately in trans-[PtL2(NH3)2].H2O and bidentately in cis-[PtL(NH3)2]L.H2O complexes through the carboxylate oxygen atoms and other sugar donor groups.
(10) The ability of beta, gamma-bidentate CrATP to act as a substrate (Danenberg and Cleland [1975].
(11) The chromium moiety of gamma,beta-bidentate CrATP slowly accepts a ligand from the sarcoplasmic reticulum Ca-ATPase to form an exchange inert coordination complex (k + 1 = 0.083 min-1; k - 2 = 0.003 min-1, 37 degrees C, 100 microM CaCl2).
(12) Four independent beta-glycerophosphates commonly act as two types of bidentate ligands, where one is the coordination to the calcium ion by the glycerol O(1) and phosphate O(22) atoms, and the other by the phosphate O(22) and O(23) atoms, thus forming the calcium coordination of a distorted square plane, respectively.
(13) For this purpose, bidentate ligands as hydroxamate and N-hydroxy-N-formylamino groups were selected as highly potent metal coordinating agents and introduced on Phe-Gly and Phe-Ala related structures.
(14) In order to investigate the function of Asp-327, a bidentate ligand of one of the zinc atoms in Escherichia coli alkaline phosphatase, and the importance of this zinc atom in catalysis, site-specific mutagenesis was used to convert Asp-327 to either asparagine or alanine.
(15) Bidentate or tridentate ligands on the other hand are able to attack the zinc ion directly; the rates are first order in enzyme and first order in ligand.
(16) All members of the new family contain a 1,3-dioxane or 1,3-dioxolane-1,3-diamine as their basic ligand, a moiety which contributes to their increased water solubility, and a bidentate acid ligand, which is responsible for their good stability.
(17) We sought evidence to determine whether contractions of the smooth muscle of the guinea pig vas deferens to ATP are in response to ATP4- or its bidentate complexes.
(18) It has been hypothesized that bidentate hydrogen bonding plays an important role in the interaction of imidazolylphenylformamidines with the H2-receptor.
(19) Deprotonated sulphonylurea act as bidentate ligands using one nitrogen and one oxygen atom (the ureido oxygen) to bind Zn2+ forming K[Zn(suphonylurea)3].
(20) An overall mechanism for inhibition by single and bidentate ligands is proposed.
Prong
Definition:
(n.) The tine of a fork, or of a similar instrument; as, a fork of two or three prongs.
(n.) A sharp-pointed instrument.
(n.) A sharp projection, as of an antler.
(n.) The fang of a tooth.
Example Sentences:
(1) To determine if the type of mechanical ventilation used (ie, face mask, nasal prongs, or endotracheal tube) was associated with GPNN, a matched case-control analysis was performed.
(2) After amputation of the closed tip, a cap from a syringe was inserted via a slit made at the base into one prong of a pair of nasal cannulae.
(3) The system called PRONG (Parallel Recording Of Neural Groups) includes a microelectrode, a lightweight reusable connector, a 24-channel FET-hybrid preamplifier, a 3-band 24-channel amplifier, a 24-channel spike monitor, high-speed digital and analog interfaces and a computer.
(4) The studies were performed with a pneumotachograph applied to the upper airway by means of an inflatable face mask or latex nasal prongs.
(5) Twenty patients did not reach the target level of 8.6 kPa (65 mmHg) PaO2 with the nasal prongs, but the reservoir cannula allowed nine of these "refractory" patients to hit this therapeutic goal, a result indicating a clear trend towards improved immediate oxygen response.
(6) The reservoir cannula Oxymizer Pendant (Chad-Therapeutics Inc.) is a nasal prong system incorporating a pendant reservoir which stores oxygen during expiration and delivers it as a bolus at the onset of inspiration.
(7) Oxygen delivery using nasal prongs was assessed using a lung model for spontaneous ventilation.
(8) The surprise offer, described by one member of the audience as having an air of desperation, appeared to form part of a two-prong strategy.
(9) Based on a model successfully used in the US , the three-pronged Operation Shield combines community mobilisation and opportunities for young people to move away from crime with harsh collective punishment for those who remain in gangs.
(10) There was the doll's house-sized two-pronged fork, and the bivalves themselves, pale and ivory against the silvered shell.
(11) Stun gun torch Facebook Twitter Pinterest The Zap Light sends one million volts between six metal prongs at the front of its torch.
(12) In Britain, there has been a three-pronged approach: the bank rate has been cut from 5% to 0.5%, a lower level than at any time in the 316-year history of the Bank of England; public borrowing has risen to around 11% of GDP, a record for peacetime; and the Bank has pumped £200bn into the money supply through quantitative easing.
(13) Nasal prongs are the usual method for delivering O2 on long-term basis, and portable O2 supply systems permit patients to use O2 continuously without significant restriction of their activities.
(14) Coronary artery segments were mounted between two L-shaped prongs in tissue baths with buffer solution.
(15) The students collect fasting samples of expired air from each other using a simple nasal prong technique.
(16) Read more The official added: “Dedicated conduct and discipline personnel deployed in field missions continue to support each field mission with the implementation of the United Nations three-pronged strategy to address sexual exploitation and abuse through prevention, enforcement and remedial actions.
(17) After studying a group of countries including Brazil, Cambodia, Mali, Peru and Tanzania, the Bank said a six-pronged approach was needed to tackle inequality.
(18) It appeared that the multi-pronged formula would inexorably lead to Greece being deemed to be in sovereign default, at least temporarily.
(19) In his meeting with the 1922 committee of Tory backbenchers on Wednesday night, the prime minister echoed a two-pronged message he delivered in a recent interview with the Spectator .
(20) The treatment works by mounting a two-pronged attack on cancer.