(superl.) Having largeness of size; of much bulk or magnitude; of great size; large.
(superl.) Great with young; pregnant; swelling; ready to give birth or produce; -- often figuratively.
(superl.) Having greatness, fullness, importance, inflation, distention, etc., whether in a good or a bad sense; as, a big heart; a big voice; big looks; to look big. As applied to looks, it indicates haughtiness or pride.
(n.) Alt. of Bigg
(v. t.) Alt. of Bigg
Example Sentences:
(1) That's why the big dreams have come from the smaller candidates such as the radical left's Jean-Luc Mélenchon.
(2) A dedicated goal makes a big difference in mobilising action and resources.
(3) We could do with similar action to cut out botnets and spam, but there aren't any big-money lobbyists coming to Mandelson pleading loss of business through those.
(4) Peter Stott of the Met Office, who led the study, said: "With global warming we're talking about very big changes in the overall water cycle.
(5) When faced with a big dilemma, the time-honoured tradition of politicians is to order an inquiry, and that is what Browne expects.
(6) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(7) "With the advent of sophisticated data-processing capabilities (including big data), the big number-crunchers can detect, model and counter all manner of online activities just by detecting the behavioural patterns they see in the data and adjusting their tactics accordingly.
(8) Evidence of the industrial panic surfaced at Digital Britain when Sly Bailey, the chief executive of Trinity Mirror, suggested that national newspaper websites that chased big online audiences have "devalued news" , whatever that might mean.
(9) Living by the "Big River" as a child, Cash soaked up work songs, church music, and country & western from radio station WMPS in Memphis, or the broadcasts from Nashville's Grand Ole Opry on Friday and Saturday evenings.
(10) It could provoke the gravest risk, that all three rating agencies declare a credit event and then there are big contagion risks for other countries," he said.
(11) If Clegg's concerns do broadly accord with Cameron's, how will the PM sell such a big U-turn to his increasingly anti-Clegg backbenchers?
(12) Lady Gaga is not the first big music star to make a new album available early to mobile customers.
(13) Without that, and without undertaking big changes, the service's future may fall into doubt, he says.
(14) "They couldn't understand until I said 'No, because I'm a big shot now, because I am in Wild Wild West and I have, like, 10 covers coming out, and I want a bigger part.'
(15) For the past six years, a big focus of my work has been bringing the first schools to some of the remotest parts of northern Sierra Leone .
(16) The Treasury said: "Britain has been at the forefront of global reforms to make banking more responsible, including big reductions in upfront cash bonuses and linking rewards to long-term success.
(17) One of the big sticking points is cash – with rich countries so far failing to live up to promise to mobilise $100bn a year by 2020 for climate finance .
(18) Reverse-phase high-performance liquid chromatography coupled with radioimmunoassay revealed that the major component of ir-endothelin corresponds to standard endothelin-1 (1-21) and the major component of ir-big endothelin corresponds to standard big endothelin (porcine, 1-39).
(19) That clearly will have a big impact on the way people relate to each other and form bonds over the coming generations.
(20) It takes more than a statistical read out and the return of big bank bonuses for a real recovery," he said.
Grave
Definition:
(v. t.) To clean, as a vessel's bottom, of barnacles, grass, etc., and pay it over with pitch; -- so called because graves or greaves was formerly used for this purpose.
(superl.) Of great weight; heavy; ponderous.
(superl.) Of importance; momentous; weighty; influential; sedate; serious; -- said of character, relations, etc.; as, grave deportment, character, influence, etc.
(superl.) Not light or gay; solemn; sober; plain; as, a grave color; a grave face.
(superl.) Not acute or sharp; low; deep; -- said of sound; as, a grave note or key.
(superl.) Slow and solemn in movement.
(n.) To dig. [Obs.] Chaucer.
(n.) To carve or cut, as letters or figures, on some hard substance; to engrave.
(n.) To carve out or give shape to, by cutting with a chisel; to sculpture; as, to grave an image.
(n.) To impress deeply (on the mind); to fix indelibly.
(n.) To entomb; to bury.
(v. i.) To write or delineate on hard substances, by means of incised lines; to practice engraving.
(n.) An excavation in the earth as a place of burial; also, any place of interment; a tomb; a sepulcher. Hence: Death; destruction.
Example Sentences:
(1) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
(2) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(3) A patient with previously treated follicular carcinoma of the thyroid developed Graves' disease with a high titre of thyroid-stimulating antibodies (TSAb).
(4) Gwendolen Morgan, the lawyer at Bindmans dealing with the case, said: "We have grave concerns about the decision to use this draconian power to detain our client for nine hours on Sunday – for what appear to be highly questionable motives, which we will be asking the high court to consider.
(5) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(6) Many reports of thyroid stimulating immunoglobulins (TSI) in relation to treatment of Graves' disease have been published and with variable results concerning prediction of permanent remission or relapse after therapy.
(7) The Duke and Duchess of Cambridge stood among the graves on 4 August last year in a moving ceremony to mark the 100th anniversary of the outbreak of war.
(8) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
(9) On the other hand, immunofluorescence in anterior pituitary cells was faint and detected in only 2 of 28 patients with Graves' disease (7.1%) after absorption of their sera with rat liver aceton powder.
(10) In conclusion, not only TBII but also T3 release-stimulating antibodies may occur in a minority of patients with long-term remission of Graves' hyperthyroidism.
(11) It is deeply moving hearing him talk now – as if from the grave – about a Christmas Day when he felt so frustrated and cut-off from his family that he had to go into the office to escape.
(12) His verdict of her that "she danced on the graves of her husband's victims.
(13) Thirty-eight bodies have been removed from the mass graves, but DNA tests have shown that none is that of a missing student.
(14) Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing.
(15) Displacement of [125I]TSH bound to fat cell membranes by both Graves' Ig and unlabeled TSH were time and temperature dependent, with similar dissociation curves, suggesting a specific binding of Graves' Ig to the membrane sites related to the TSH receptor in the fat cells.
(16) We have obtained sera from 42 patients with active Graves' disease and no known connective tissue disorders.
(17) A total of 5.8% abnormalities were found including nodular disease, thyroiditis, Graves' disease, hypothyroidism, simple goiter, and iatrogenic hyperthyroidism.
(18) LATS was measured with the double isotope technique in IgG serum concentrates of 23 patients with Graves' disease before treatment and of 18 patients during treatment with carbimazole and triiodothyronine.
(19) To elucidate whether insulin-induced hypoglycemia enhances the release of beta-endorphin in man, plasma extracts obtained from healthy subjects and patients with Graves' disease before and 45 min after insulin injection were subjected to gel chromatography, and the fractions obtained were measured by RIA for beta-endorphin.
(20) From the findings of abnormalities in intrathyroidal T cell subsets, we suggest that the decrease in the function of suppressor T cells within the thyroids of Graves' disease patients may be due to a decrease in CD4+2H4+ cells within thyroid tissue.