(superl.) Having largeness of size; of much bulk or magnitude; of great size; large.
(superl.) Great with young; pregnant; swelling; ready to give birth or produce; -- often figuratively.
(superl.) Having greatness, fullness, importance, inflation, distention, etc., whether in a good or a bad sense; as, a big heart; a big voice; big looks; to look big. As applied to looks, it indicates haughtiness or pride.
(n.) Alt. of Bigg
(v. t.) Alt. of Bigg
Example Sentences:
(1) That's why the big dreams have come from the smaller candidates such as the radical left's Jean-Luc Mélenchon.
(2) A dedicated goal makes a big difference in mobilising action and resources.
(3) We could do with similar action to cut out botnets and spam, but there aren't any big-money lobbyists coming to Mandelson pleading loss of business through those.
(4) Peter Stott of the Met Office, who led the study, said: "With global warming we're talking about very big changes in the overall water cycle.
(5) When faced with a big dilemma, the time-honoured tradition of politicians is to order an inquiry, and that is what Browne expects.
(6) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(7) "With the advent of sophisticated data-processing capabilities (including big data), the big number-crunchers can detect, model and counter all manner of online activities just by detecting the behavioural patterns they see in the data and adjusting their tactics accordingly.
(8) Evidence of the industrial panic surfaced at Digital Britain when Sly Bailey, the chief executive of Trinity Mirror, suggested that national newspaper websites that chased big online audiences have "devalued news" , whatever that might mean.
(9) Living by the "Big River" as a child, Cash soaked up work songs, church music, and country & western from radio station WMPS in Memphis, or the broadcasts from Nashville's Grand Ole Opry on Friday and Saturday evenings.
(10) It could provoke the gravest risk, that all three rating agencies declare a credit event and then there are big contagion risks for other countries," he said.
(11) If Clegg's concerns do broadly accord with Cameron's, how will the PM sell such a big U-turn to his increasingly anti-Clegg backbenchers?
(12) Lady Gaga is not the first big music star to make a new album available early to mobile customers.
(13) Without that, and without undertaking big changes, the service's future may fall into doubt, he says.
(14) "They couldn't understand until I said 'No, because I'm a big shot now, because I am in Wild Wild West and I have, like, 10 covers coming out, and I want a bigger part.'
(15) For the past six years, a big focus of my work has been bringing the first schools to some of the remotest parts of northern Sierra Leone .
(16) The Treasury said: "Britain has been at the forefront of global reforms to make banking more responsible, including big reductions in upfront cash bonuses and linking rewards to long-term success.
(17) One of the big sticking points is cash – with rich countries so far failing to live up to promise to mobilise $100bn a year by 2020 for climate finance .
(18) Reverse-phase high-performance liquid chromatography coupled with radioimmunoassay revealed that the major component of ir-endothelin corresponds to standard endothelin-1 (1-21) and the major component of ir-big endothelin corresponds to standard big endothelin (porcine, 1-39).
(19) That clearly will have a big impact on the way people relate to each other and form bonds over the coming generations.
(20) It takes more than a statistical read out and the return of big bank bonuses for a real recovery," he said.
Sig
Definition:
(v. t.) Urine.
Example Sentences:
(1) The majority of tumor cells in all lymphosarcoma cases were of the centroblastic type, and in two cases in which the presence of SIg was assayed, the majority of tumor cells were SIg-positive.
(2) The proportion of SIg carrying cells within the population forming EA-rosettes was between 11 and 26-4%.
(3) Nylon-adherent cells were highly enriched for surface immunoglobulin (SIg) bearing B lymphocytes (95.5%) and nonadherent cells for SIg negative non-B cells, presumably T lymphocytes (96.3%).
(4) We have investigated the possible physical interactions between CR, receptors for the Fc gamma R and surface Ig (sIg) on the surface membrane of murine B lymphocytes.
(5) A subpopulation of appendix sIg-negative, RTLA-negative cells has a relatively high concentration of RT2.
(6) SIg-positive lymphocytes (B cells) and T lymphocytes were not effective in mediating ADCC against either CRBC or Chang cell targets.
(7) Modulation of surface immunoglobulin (sIg) with anti-mu, an early membrane activation event, occurred normally on B cells from the spleens of PC-mice.
(8) Those TIL expressing activation antigens were CD2+, SIg-.
(9) This treatment did not affect the proportions of Lyt-2+, L3T4+, or sIg+ cells in the population, however, indicating that the augmentation in PFC was not due to changes in the ratio of T to B cells.
(10) The results of lymphocyte subpopulation studies revealed a decrease of CD4+ cells and a decrease of surface immunoglobulin (sIg)-positive B lymphocytes.
(11) In SLL, 55 were M-rosette positive (67.07%) and 72 SIg positive (87.8%), with weak fluorescence in 63 and strong fluorescence in 9 cases.
(12) The expression of kappa and lambda light chains in surface immunoglobulin (sIg) molecules on B lymphocytes differentiating from murine pre-B cell clones in vitro was analyzed.
(13) With CRBC targets MICC was mediated by polymorphonuclear leukocytes, macrophages, sIg-positive lymphocytes (B cells), and sIg-negative lymphocytes.
(14) Among the B-CLL, cells with high SIg content were either T1+ or T1- and more likely FMC7+.
(15) Antibody N297 (DQ specific), previously shown to react with an epitope expressed on human B cells but not on mitogen-induced T cells, reacted only with sIg+ cells in 42 of 53 horses tested.
(16) At this time, the proportions of low mobility (LM) and SIG-bearing lymphocytes (B cells) were reduced respectively to 28% (control 54%) and 20% (control 45%).
(17) A sudden increase in the number of mitogen-reactive, sIg+ B lineage cells occurs within 24 h between days 16 and 17.
(18) The significance of this spontaneous appearance of fetal sIg cells is discussed.
(19) The finding of sIg light chain in pre-B cell leukemias and in the REH cell line, suggests that these leukemic cells are further differentiated along the B-cell lineage than was previously believed.
(20) The malignant cells of WM patients differed from those of MM in the reactivity with FMC7, being positive in 10 out of 11 cases, and in their high expression of B1, Ia and SIg with a predominant mu+ phenotype.