(superl.) Having largeness of size; of much bulk or magnitude; of great size; large.
(superl.) Great with young; pregnant; swelling; ready to give birth or produce; -- often figuratively.
(superl.) Having greatness, fullness, importance, inflation, distention, etc., whether in a good or a bad sense; as, a big heart; a big voice; big looks; to look big. As applied to looks, it indicates haughtiness or pride.
(n.) Alt. of Bigg
(v. t.) Alt. of Bigg
Example Sentences:
(1) That's why the big dreams have come from the smaller candidates such as the radical left's Jean-Luc Mélenchon.
(2) A dedicated goal makes a big difference in mobilising action and resources.
(3) We could do with similar action to cut out botnets and spam, but there aren't any big-money lobbyists coming to Mandelson pleading loss of business through those.
(4) Peter Stott of the Met Office, who led the study, said: "With global warming we're talking about very big changes in the overall water cycle.
(5) When faced with a big dilemma, the time-honoured tradition of politicians is to order an inquiry, and that is what Browne expects.
(6) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(7) "With the advent of sophisticated data-processing capabilities (including big data), the big number-crunchers can detect, model and counter all manner of online activities just by detecting the behavioural patterns they see in the data and adjusting their tactics accordingly.
(8) Evidence of the industrial panic surfaced at Digital Britain when Sly Bailey, the chief executive of Trinity Mirror, suggested that national newspaper websites that chased big online audiences have "devalued news" , whatever that might mean.
(9) Living by the "Big River" as a child, Cash soaked up work songs, church music, and country & western from radio station WMPS in Memphis, or the broadcasts from Nashville's Grand Ole Opry on Friday and Saturday evenings.
(10) It could provoke the gravest risk, that all three rating agencies declare a credit event and then there are big contagion risks for other countries," he said.
(11) If Clegg's concerns do broadly accord with Cameron's, how will the PM sell such a big U-turn to his increasingly anti-Clegg backbenchers?
(12) Lady Gaga is not the first big music star to make a new album available early to mobile customers.
(13) Without that, and without undertaking big changes, the service's future may fall into doubt, he says.
(14) "They couldn't understand until I said 'No, because I'm a big shot now, because I am in Wild Wild West and I have, like, 10 covers coming out, and I want a bigger part.'
(15) For the past six years, a big focus of my work has been bringing the first schools to some of the remotest parts of northern Sierra Leone .
(16) The Treasury said: "Britain has been at the forefront of global reforms to make banking more responsible, including big reductions in upfront cash bonuses and linking rewards to long-term success.
(17) One of the big sticking points is cash – with rich countries so far failing to live up to promise to mobilise $100bn a year by 2020 for climate finance .
(18) Reverse-phase high-performance liquid chromatography coupled with radioimmunoassay revealed that the major component of ir-endothelin corresponds to standard endothelin-1 (1-21) and the major component of ir-big endothelin corresponds to standard big endothelin (porcine, 1-39).
(19) That clearly will have a big impact on the way people relate to each other and form bonds over the coming generations.
(20) It takes more than a statistical read out and the return of big bank bonuses for a real recovery," he said.
Slough
Definition:
(a.) Slow.
(n.) A place of deep mud or mire; a hole full of mire.
(n.) A wet place; a swale; a side channel or inlet from a river.
() imp. of Slee, to slay. Slew.
(n.) The skin, commonly the cast-off skin, of a serpent or of some similar animal.
(n.) The dead mass separating from a foul sore; the dead part which separates from the living tissue in mortification.
(v. i.) To form a slough; to separate in the form of dead matter from the living tissues; -- often used with off, or away; as, a sloughing ulcer; the dead tissues slough off slowly.
(v. t.) To cast off; to discard as refuse.
Example Sentences:
(1) Mucosal sloughing with hemorrhage and infarction were observed at 3 hours.
(2) More suppliers have told the Guardian of extensive negotiations with Amazon staff in Slough, adding to the impression that the company carries out important trading activities in the UK and so could be liable for tax.
(3) In mammalian small intestine absorptive cells are known to migrate from the villus base to the villus tip from which they slough.
(4) The most marked effect of the ZnSO4 took the form of necrosis and sloughing of surface cells in both strains one-half day after ZnSO4 irrigation.
(5) Cameron’s call for the Malaysian political class to fight corruption came as he pitched the country’s financiers the chance to invest in £17bn worth of UK infrastructure projects ranging from a Leeds orbital road route, Slough town centre and prime residential properties along the Thames.
(6) The histopathologic features include peritubular sclerosis, small vessel sclerosis, premature germ cell sloughing, and variable degrees of hypospermatogenesis.
(7) Changes in sperm head morphology are caused by (1) a dramatic reshaping and consolidation of the acrosome in which excess plasma membrane overlying it is sloughed as a cluster of vesicles, (2) a reorientation of the nucleus almost parallel to the axis of the tail and (3) distal movement of the droplet from its initial envelopment of the nucleus to an eccentric position on the anterior segment of the midpiece.
(8) Acute hypothermia induced a sloughing of cells from the villi into the lumen of the gut, as indicated by an increased DNA in luminal washings.
(9) Toxic epidermal necrolysis results in skin sloughing that resembles a partial-thickness thermal injury.
(10) Scanning electron microscopy revealed that in diabetic BB rats there was consistent evidence of swollen cells, raised nuclei, and sloughing of nuclei in endothelial cells of the aorta.
(11) However, after sloughing of labelled cells in the intestinal lumen, Pu was reabsorbed by the distal epithelial cells.
(12) It places the implant deep to prevent skin slough and irregularities in skin surface contour.
(13) Newer communities have settled in towns and cities such as Milton Keynes, Slough, Northampton, Southampton, and in London, notably Ealing, Tower Hamlets and Newham.
(14) Sloughing vesiculobullous oral lesions are a frequent component.
(15) Within 1 day of injury, columnar epithelium sloughed intact from the trachea with a concomitant reduction of nearly 35% in the basal cell population.
(16) Early changes (0-2 hours) included focal tumor and endothelial cell vacuolation and swelling as well as sloughing of tumor cells into papillary spaces.
(17) Histologically, the 4.0 ppm animals demonstrated bronchiolar epithelial necrosis and sloughing, bronchiolar edema with macrophages, and focal pulmonary edema.
(18) Ciliated cells had a slightly vesiculated cytoplasm, and many were in the process of being sloughed from the epithelial surface.
(19) Preliminary histochemical studies show that terminin is also found in the superficial epithelial layer of the esophagus, where terminal differentiation is followed by apoptosis and sloughing off into the lumen.
(20) In both the mouse and the rat, some of the superficial cells sloughed between fetal day 18 or 19 and the day of birth.