(1) Familiar vestiges of premodern theory are found in such expressions as "bighearted," "warmhearted," "brokenhearted," and so on.
(2) He also called on cabinet ministers to end the feuding created by the campaign on the referendum on AV saying "it requires people to behave in a bighearted and big way – that is what we are going to do".
Novel
Definition:
(a.) Of recent origin or introduction; not ancient; new; hence, out of the ordinary course; unusual; strange; surprising.
(a.) That which is new or unusual; a novelty.
(a.) News; fresh tidings.
(a.) A fictitious tale or narrative, professing to be conformed to real life; esp., one intended to exhibit the operation of the passions, and particularly of love.
(a.) A new or supplemental constitution. See the Note under Novel, a.
Example Sentences:
(1) Moreover in MIT-1, the size of the novel polypeptide was not that predicted of the precursor (44.9 kDa) but was about 39 kDa, the same size as the authentic GS gamma polypeptide in CYT-4.
(2) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(3) A novel prostaglandin E2 analogue, CL 115347, can be administered transdermally on a long-term basis.
(4) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
(5) Experiment 3 showed that the color-induced increase in odor intensity is not due to subjects' preexperimental experience with particular color-odor combinations, because the increase occurred with novel ones.
(6) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(7) But what they take for a witticism might very well be true; most of Ellis's novels tell more or less the same story, about the same alienated ennui, and maybe they really are nothing more than the fictionalised diaries of an unremarkably unhappy man.
(8) Cyclosporine is a fungal endecapeptide of novel chemical structure that causes preferential inhibition of T helper cells.
(9) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(10) Her novels have an enduring and universal appeal and she is recognised as one of the greatest writers in English literature.
(11) The complex problems have been successfully managed with novel guiding catheter shapes and ultralow profile balloons.
(12) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
(13) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
(14) This novel coumarin derivative significantly inhibited skin tumor initiation by DMBA in SENCAR mice when given at a dose of 200 nmol, 5 min (69% inhibition) or 24 h (76% inhibition) prior to initiation.
(15) Using a novel method for joining DNA sequences, we have exploited this difference between the two enzymes to identify the regions of the RT that contribute to the compounds' inhibitory activities.
(16) It may thus represent an artifact of the labeling procedure rather than a novel basophil-derived prostaglandin.
(17) Endothelin-1 (ET-1) is a novel vasoconstricting and cardiotonic peptide that is synthesized by the vascular endothelium.
(18) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
(19) Pretreatment with a novel CRF antagonist, alpha-helical CRF9-41 (130.9 nmol i.t.v.
(20) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.