(n.) The act or process of one who, or that which, binds.
(n.) Anything that binds; a bandage; the cover of a book, or the cover with the sewing, etc.; something that secures the edge of cloth from raveling.
(pl.) The transoms, knees, beams, keelson, and other chief timbers used for connecting and strengthening the parts of a vessel.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Compulsory
Definition:
(a.) Having the power of compulsion; constraining.
(a.) Obligatory; enjoined by authority; necessary; due to compulsion.
Example Sentences:
(1) These results provide further data which counter the sometimes extreme advocates of the view that compulsory admission and treatment of patients with psychiatric illness is never acceptable.
(2) A guide, £44pp, is compulsory ( rscn.org.jo ) 2 Discover the Nuweiba coast: Red Sea, Egypt Beach, Nuweiba, Sinai, Egypt.
(3) Lloyds said it would achieve many of the job cuts through making less use of contractors and voluntary severance but admitted that some compulsory redundancies may be inevitable.
(4) The results are most consistent with a general non-compulsory model for the formation of a ternary complex between carrier, phenylalanine molecule and a sodium ion, which can be formed from either binary complex, i.e., either species can combine first to the carrier.
(5) Revenue from the tax will be used to increase compulsory pension payments from 9% to 12%.
(6) Of these patients 90 had to be jugded by a court commission with regard to further compulsory hospitalization.
(7) Both alcohol oxidation and acetaldehyde reduction follow a compulsory ordered pathway, with coenzyme binding first.
(8) However, an increasing body of experts argues something must be done to arrest disengagement by winning over this so-called Generation Y, born after 1982, who are predicted to be poorer than their parents, and according to Ipsos Mori research, have a record low level of trust in their fellow man.Guy Lodge, of the IPPR thinktank, makes the case for an even more radical solution – compulsory voting for first-timers.
(9) Compulsory national testing for four- and five-year-olds in England from 2016 is to be introduced as part of sweeping changes being proposed to early years and primary education.
(10) In this context, the present article makes an analysis of the main ethical and legal problems posed by HIV infection, in the framework of Portuguese law, with special focus on: a) Conflict between the necessary protection of public health by the State and the protection of fundamental rights and freedoms of the citizens; b) Inadequacy of the existent laws to fight contagious diseases to HIV infection; c) Discrimination; d) Testing and compulsory hospitalization versus informed consent; e) Confidentiality; f) Voluntary contagion.
(11) The scheme comes ahead of government plans to make such referrals compulsory after criticism that Britain’s biggest banks are failing to provide sufficient credit to a sector the government sees as having an important role in stimulating the economy.
(12) Both groups agreed over most points, except on the desirability of compulsory vocational training: 42 of the trainees thought this to be desirable compared with 35 of the teachers.The composite scheme favoured by both trainees and teachers offered an initial period in general practice together with an organized course of seminars throughout the training period.
(13) Its role in reversing the compulsory rotation at the beginning of flexion can now easily be explained: since it is an extensor, the flexion would cause its passive elongation, against which its mere tonus causes rotation.
(14) They were selected by a method to form a representative sample of all West Jerusalem compulsory kindergarten classes in 1971.
(15) In regard to therapy, the authors believe that surgery is compulsory for patients showing clinical signs of upper airway obstruction despite suppressive therapy or when the lesion shows signs of malignant degeneration.
(16) These standards must be strengthened and made compulsory before targets are raised any further.
(17) In order to contribute to the discussion of compulsory vaccinations a brief review of those vaccines that have been extensively used so far is presented.
(18) The onset of smoking in the oldest male group in this rural area occurred in the first years after the war (first land confiscation) while in the group from 70 to 74 years of age it occurred in the years of compulsory crop-purchase system.
(19) Most hospitals in California were found to provide continuing education opportunities for physical therapists, but physical therapists in small hospitals and in private-profit hospitals could be at a disadvantage financially if continuing education becomes compulsory for relicensure.
(20) Very low levels of protection were detected, regarding both compulsory and optional vaccines as well as antimalarial protection.