(n.) The act or process of one who, or that which, binds.
(n.) Anything that binds; a bandage; the cover of a book, or the cover with the sewing, etc.; something that secures the edge of cloth from raveling.
(pl.) The transoms, knees, beams, keelson, and other chief timbers used for connecting and strengthening the parts of a vessel.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
(a.) Lying, resting, or imposed, as a duty or obligation; obligatory; always with on or upon.
(a.) Leaning or resting; -- said of anthers when lying on the inner side of the filament, or of cotyledons when the radicle lies against the back of one of them.
(a.) Bent downwards so that the ends touch, or rest on, something else; as, the incumbent toe of a bird.
(n.) A person who is in present possession of a benefice or of any office.
Example Sentences:
(1) The umpires allow them a different one, perhaps because the previous incumbent was wet - it landed in a puddle, where the water-sucking thing had egested, apparently.
(2) Therefore, it is incumbent upon clinicians to know the signs and symptoms of using steroids, and to be familiar with the clinical indications for urine testing.
(3) Crisis engulfs Gabon hospital founded to atone for colonial crimes Read more At least seven people died and more than 1,000 were arrested in violent protests following the announcement of the election result earlier this month, which the leader of the opposition, Jean Ping, said Bongo, the incumbent, had rigged.
(4) Incumbents facing competitive re-election battles in November, including Ron Johnson of Wisconsin, Marco Rubio of Florida, Rob Portman of Ohio, John McCain of Arizona and Richard Burr of North Carolina, voted for that bill, which had the backing of the NRA.
(5) Akin, a six-term congressman running against incumbent Democratic senator Claire McCaskill, was asked in an interview broadcast Sunday on St Louis television station KTVI if he would support abortions for women who have been raped.
(6) The incumbent mayor has set his sights on stronger powers over the London economy as he seeks re-election for a second term on 3 May.
(7) He told the conference: "As you succeed in getting more and more business, the incumbent's tactic is to retreat slowly.
(8) If that suggests that Norwegian and Australian voters are poised to reward these centre-left incumbents for their management, think again.
(9) All the bridge-building exercises in the world will not help Woodward if he fails in his most pressing task: to find the right replacement for Moyes and deliver the players the new incumbent requires.
(10) It is incumbent on the US, Britain and France to do their utmost to help the country win the peace.
(11) Polls released this week showed the radical left anti-austerity Syriza party still in the ascendant, and analysts have expressed doubts that the incumbent New Democracy party will be able to overturn its lead.
(12) Yet even this may yet be tempered by the realisation that life in the assembly will be easier to manage due to the departure of the previous incumbent, Leighton Andrews.
(13) During the past 11 elections where an incumbent ran for re-election and there was a Gallup poll (all since 1940, save 1944), there has been a statistical trend for the president's approval rating to rise during the campaign.
(14) That is, an incumbent Democrat, for example, would tend to do better than a new Democrat running for the same seat.
(15) The increased accessibility of sports medicine clinics makes it incumbent on the physician to be familiar with a wide range of differential diagnoses.
(16) There is a certain provincialism – this is a state where people really do still expect the candidates to show up.” Most agree this favours the incumbent.
(17) It is incumbent upon the physician first to decide what is the most likely diagnosis to be correct; and then to undertake treatment indicated for that diagnosis.
(18) Maréchal-Le Pen has a chance of winning, and becoming France's first Front National MP in decades, despite a difficult battle against the favourite, the incumbent, from the right wing of Sarkozy's UMP party, who has won six successive parliamentary elections.
(19) 8 March 2008: Anwar leads an opposition coalition to wrest a third of parliament's seats and five states from the incumbent National Front coalition, which has ruled Malaysia since it became independent from Britain in 1957.
(20) Issa Hayatou, president of Caf, who is among 10 Fifa executive committee members to be questioned in Zurich, has declared the continent united in its support of the incumbent.