(n.) The act or process of one who, or that which, binds.
(n.) Anything that binds; a bandage; the cover of a book, or the cover with the sewing, etc.; something that secures the edge of cloth from raveling.
(pl.) The transoms, knees, beams, keelson, and other chief timbers used for connecting and strengthening the parts of a vessel.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Loose
Definition:
(superl.) Not precise or exact; vague; indeterminate; as, a loose style, or way of reasoning.
(superl.) Unbound; untied; unsewed; not attached, fastened, fixed, or confined; as, the loose sheets of a book.
(superl.) Free from constraint or obligation; not bound by duty, habit, etc. ; -- with from or of.
(superl.) Not tight or close; as, a loose garment.
(superl.) Not dense, close, compact, or crowded; as, a cloth of loose texture.
(superl.) Not strict in matters of morality; not rigid according to some standard of right.
(superl.) Unconnected; rambling.
(superl.) Lax; not costive; having lax bowels.
(superl.) Dissolute; unchaste; as, a loose man or woman.
(superl.) Containing or consisting of obscene or unchaste language; as, a loose epistle.
(n.) Freedom from restraint.
(n.) A letting go; discharge.
(a.) To untie or unbind; to free from any fastening; to remove the shackles or fastenings of; to set free; to relieve.
(a.) To release from anything obligatory or burdensome; to disengage; hence, to absolve; to remit.
(a.) To relax; to loosen; to make less strict.
(a.) To solve; to interpret.
(v. i.) To set sail.
Example Sentences:
(1) Factors associated with higher incidence of rejection included loose sutures, traumatic wound dehiscence, and grafts larger than 8.5 mm.
(2) He is a leader and helps manage the defence, while Pablo Armero can be a bit of a loose cannon but he is certainly a talented player.
(3) This study investigates the use of the incentive inspirometer to observe the effects of tight versus loose clothing on inhalation volume with 17 volunteer subjects.
(4) Security forces have also tried to wrest back the Sunni stronghold of Tikrit from a loose alliance of Isis fighters, other jihadist groups and former Saddam Hussein loyalists.
(5) His shot, though, was pawed on to the inside of the post by David Marshall and it was left to Victor Wanyama to lash the loose ball into the empty net.
(6) We had our bicycles and we were just turned loose all day.
(7) Our model is a development of previous models, but differs in several respects: the overall activity is assumed to be dependent on the error level, the effect of errors in the translating system, giving rise to additional errors in the succeeding generation of products, is explicitly included as a special term in our model, and scavenging enzymes are assumed to break down and eliminate products with a loose structure.
(8) Clearance into the mediastinum may be the major pathway for liquid sequestered in the loose, binding connective tissue.
(9) Two tibial components (2%) were believed to be mechanically loose, but no revisions for mechanical loosening were done.
(10) The results indicate that the optimal cruciform loop size is four bases, with loose 'breathing' at the first base pair at the top of the cruciform stem at 37 degrees C, and little or no opening of base pairs at the four-way junction.
(11) Theresa May’s plan for a loose alliance with the Democratic Unionists to prop up her government was thrown into confusion on Saturday night after the Northern Ireland party contradicted a No 10 announcement that a deal had been reached.
(12) We have also confirmed loose linkage with the marker (Mfd22, locus D4S171) used to establish the initial assignment of the disorder to chromosome 4.
(13) As demonstrated by Ficoll density gradient centrifugation and HPLC gel filtration, the cholate dialysis method made the reductase bind tightly to the liposomal membranes, while the incubation with the preformed vesicles made the reductase bind loosely to the membranes.
(14) In its more loose, common usage, it's a game in which the rivalry has come to acquire the mad, rancorous intensity of a Celtic-Rangers, a Real Madrid-Barcelona, an Arsenal-Tottenham, a River Plate-Boca Juniors.
(15) Twenty-one of 24 adult male and female cattle egrets (Bubulcus ibis ibis) collected in Geneva County, Alabama had numerous white cyst-like structures (1,466 microns X 354 microns) found within the loose connective tissues of the skeletal muscles of the inguinal region, beneath the serosa of the proventriculus and in the heart beneath the epicardium (one adult male bird).
(16) SCLC variant lines could further be divided into (a) biochemical variant lines having variant biochemical profile but retaining typical SCLC morphology and growth characteristics; and (b) morphological variant (SCLC-MV) lines having variant biochemical profile, altered morphology (features of large cell undifferentiated carcinoma) and altered growth characteristics (growth as loosely attached floating aggregates, relatively short doubling times and cloning efficiencies).
(17) At rostral levels, one third of the tracts are loosely built forming a king of curtain, while they become more compact at caudal levels.
(18) (1) The prerequisite for development of cholesteatoma is a cholesteatoma bed, that is a loose subepithelial connective tissue layer which acts as a nutrient bed and makes papillary growth of squamous epithelium possible.
(19) His mother is Denise Welch, late of Corrie and Loose Women, and his father his Tim Healy, who was briefly famous 30 years ago for his role in Auf Wiedersehen, Pet.
(20) Initially, 4-5 days post-operative, the plasma clot maintained the grafted cells in a loose sponge-like sack at the site of implantation.