(1) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(2) Among a family of 8 children, 4 presented typical clinical and biological abnormalities related to mannosidosis.
(3) The HTCA is promising as a potential tool for studying the biology of tumors.
(4) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(5) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
(6) Chromatography and immunoassays are the two principal techniques used in research and clinical laboratories for the measurement of drug concentrations in biological fluids.
(7) Biological magnification of insecticides and PCB's occurred in both lakes.
(8) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(9) No biologic investigation of the hemostatic impairment could be performed under the emergency conditions of this field study.
(10) It is the absorbed dose in joules per gram that is biologically significant and the data shows that the mean absorbed dose to death within either sex shows no significant difference with respect to age or weight, but that the difference between the sexes are significant, particularly among the aged ex-breeders.
(11) Although chronologic age may not be a good predictor of pregnancy outcome, adolescents remain a high-risk group due to factors which are more common among them such as biologic immaturity, inadequate prenatal care, poverty, minority status, and low prepregnancy weight, and because factors associated with an early adolescent pregnancy, such as low gynecologic age, may continue to influence the outcome of subsequent pregnancies.
(12) The analysis of blood lead concentration revealed an evident biological response to this environmental change: there was a decrease in blood lead level between 1977 and 1987, in both the countryside (control group) and, to a lesser extent, in the city.
(13) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
(14) Thus, introduction of arginine in position 5 with a hydrophobic amino acid in position 6 is compatible with high potency in several biological systems and results in compounds with lowered potency to release histamine compared to homologous peptides with tyrosine in position 5 and D-arginine in position 6.
(15) The crystal structure of the biological stain, "acridine orange," has been determined.
(16) Improvement of its particularly poor prognosis requires therefore early screening based on reliable biological markers.
(17) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
(18) That’s important, because Ebola is the Isis of biological agents .
(19) Men older than 75 showed a slightly higher mortality during the first year, but there were seemingly no relationships of tumor-biological or clinical significance between age at diagnosis and long-term relative survival.
(20) Since the employment of microwave energy for defrosting biological tissues and for microwave-aided diagnosis in cryosurgery is very promising, the problem of ensuring the match between the contact antennas (applicators) and the frozen biological object has become a pressing one.
Consanguinity
Definition:
(n.) The relation of persons by blood, in distinction from affinity or relation by marriage; blood relationship; as, lineal consanguinity; collateral consanguinity.
Example Sentences:
(1) Legislation governing adoption has attempted to make the adoptive family the equivalent of a consanguinal one, with varying degrees of success.
(2) Two strikingly similar brothers issued from consanguineous parents in the second degree present the following patterns of anomalies: retardation of growth, mental deficiency, ocular abnormalities, pectus excavatum and camptodactyly.
(3) Parental consanguinity suggests that an autosomal recessive mutation is the likely aetiology.
(4) Any patient with a fairly symmetrical 'quiet' eye disease, especially if congenital, should be suspected of having an hereditary disease--presumably due to a recessive gene, even if the parents are not consanguineous, but possibly due to a mutation which could prove dominant; a search of the literature in such cases is useful.
(5) Taking advantage of the availability of an archive of consanguineous marriages that gives accurate estimates of consanguinity in Italy, it has been possible to calculate the increase of first- and second-cousin marriages among 624 couples of cystic fibrosis (CF) parents over the general population.
(6) Consanguinity of the kindreds could not be established.
(7) In this case, lower fertility might be expected in consanguineous marriages, only because of a higher probability of homozygosis of deleterious genes.
(8) The differences between consanguineous and non-consanguineous marriages in terms of total foetal loss, perinatal, neonatal, postneonatl and infant mortality rates showed only marginal differences that attain statistical significance only because of the large sample size involved.
(9) Two subjects (brother and sister), children of consanguineous parents, showed a typical congenital corneal dystrophy associated with mental retardation and a bilateral malformation of the little finger.
(10) Impaired IL-2 activity was found in 15 of the 29 consanguineous relatives.
(11) Parental consanguinity in those with genetically determined causes of visual impairment was high compared with those with nongenetic causes (79% vs 33.3%, P < .05).
(12) Three sibs, a boy and two girls, born to Moroccan consanguineous parents, were affected with a syndrome characterized by brittle hair, mental retardation, short stature, ataxia, and gonadal dysfunction.
(13) The mores that encouraged consanguineous marriages had the lowest final lethal-gene frequencies.
(14) The comparison between 1,302 adults born from consanguineous marriages underlines a heavy depression of mental abilities.
(15) In XIX century generations consanguinity was very low (alpha coefficient 7 x 10(-5) which may be explained by the exogamic tradition of the population; this acted as a factor opposed to random drift.
(16) There was no significant difference in the prevalence of congenital malformations between Hindus (2.0%) and Muslims (2.7%) but amongst Muslims with consanguinity the prevalence of congenital malformation was 4.6 per cent compared to 2.3 per cent in non-consanguineous Muslim spouses (P less than 0.05).
(17) Consanguineous marriages are strongly favoured among the peoples of South India.
(18) The gene frequency was only 7-9.10 minus 5, but the consanguinity rate was high in the families observed.
(19) Three cases of cleidocranial dysostosis from two unrelated consanguineous families are reported.
(20) Because the parents of the siblings are consanguineous, this is probably a genetically determined condition with an autosomal recessive type of transmission.