(a.) Cold and cutting; cheerless; as, a bleak blast.
(a.) A small European river fish (Leuciscus alburnus), of the family Cyprinidae; the blay.
Example Sentences:
(1) "The results present a remarkably bleak portrait of life in the UK today and the shrinking opportunities faced by the bottom third of UK society," said the head of the project, Professor David Gordon of Bristol University.
(2) The study says: "The short-term outlook for the labour market looks bleak.
(3) He'd later carry this over into Netflix's House Of Cards but before that, TV had already begun to emulate this new, bleak, antiheroic maturity with a cycle of dark, longform, acclaimed dramas, commencing with The Sopranos and culminating in Breaking Bad .
(4) This is training that predators rely upon,” she says in the book, “It is, perhaps, a form of gender-wide grooming.” For Caro, the opportunity of the book was to “place the blame where it lies,” she says, “squarely on the shoulders of those who use their power to exploit and damage others.” For all its bleakness, I drew comfort from the stories of the other contributors.
(5) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(6) He said the “bleak alternative” would have been to go through numerous probate courts while distant relatives of Gurlitt made their claims on the collection.
(7) After dismissing the ending of Revolutionary Road as "falsely bleak" and telling his audience that "there's something goofy about American literature since modernism came to an end", the celebrated author of Freedom and The Corrections moved on to social media .
(8) Bleak jokes and cartoons have been circulating for weeks in the anti-Assad camp on the theme of barrel bombs serving as ballot boxes.
(9) "I have such passion for what I do that I can't see it as bleak.
(10) It is to be hoped that pharmaceutical developments will improve the current bleak picture in which there are no proven treatments for ischaemic stroke or intracerebral haemorrhage.
(11) Next month Commonwealth leaders gather in Sri Lanka amid a bleak human rights situation as the country emerges from two decades of civil war that saw 40,000 civilians lose their lives .
(12) Things began to look bleak for the Saddlers when Chelsea extended their lead four minutes from the interval.
(13) The compelling television series The Returned , which concludes on Sunday on Channel 4, and several award-winning titles from French authors are earning fresh international plaudits for Gallic storytelling and proving that it is not only Norway, Sweden and Denmark that can offer a bleak outlook and a half-lit landscape.
(14) The alternative is to leave our young children facing a bleak future.
(15) Concomitant other distant metastases conferred a bleak prognosis.
(16) "I don't know why," he says, but it's something that didn't even happen at his lowest ebb: amid the bleakness of the early 70s, he somehow kept sporadically producing incredible songs: Til I Die, This Whole World, Sail On Sailor… There's always touring, however.
(17) The forecast is for one of the coldest winters in Syria for 100 years, with more than four million people displaced inside the country and an estimated two million who have fled into neighbouring countries, facing an increasingly bleak existence.
(18) The Reading group reaction to Bleak House has been overwhelmingly positive.
(19) The childish vulnerability she brings out in Sara balances out the visual bleakness of the film.
(20) The bleak outlook for patients with marrow necrosis based on early experience in adults with disseminated malignancy does not appear to apply to children with ALL.
Pallid
Definition:
(a.) Deficient in color; pale; wan; as, a pallid countenance; pallid blue.
Example Sentences:
(1) In order to examine the role of the basal ganglia (BG) in the regulation of basic movement parameters, we recorded extracellularly from pallidal neurons in conscious monkeys during the performance of a sequential wrist movement task which was composed of a series of holds and ballistic jumps.
(2) The tasks were designed to dissociate several modes and parameters of movement to see whether pallidal neurons would discharge in relation to one and not the others.
(3) A related growth factor, epidermal growth factor (EGF), has also been reported to be present in pallidal regions of rat brain.
(4) It is concluded that, of the compounds identified, solstitialin A 13-acetate and cynaropicrin have toxic potential in cell cultures, containing cells from the substantia nigra of the rat, the specificity of action to cells of the substantia nigra remains to be shown, and that a toxic action in the midbrain may contribute to the nigro-pallidal encephalomalacia, caused by the ingestion of the yellow star thistle by horses.
(5) This response pattern was present in 39% of the pallidal records, and appeared to be elicited by the auditory components of the CS and US.
(6) SITS was chosen for the pallidal injections because it is not taken up by fibers-of-passage.
(7) The proposed changes in nomenclature are based on the analysis of topographical relationships between nigral, pallidal, and cerebellar projections to the thalamus studied in 13 rhesus monkeys with the use of autoradiography technique.
(8) However, these two pallidal afferents arborize according to a different pattern in GPe and GPi.
(9) The first excitation was assumed to be monosynaptically driven since it was not affected by pallidal lesion or transsection of the internal capsule.
(10) He came within 10 minutes of passing much of that burden on to José Mourinho, whose Chelsea side once again looked pallid and likely to slump to a fourth league defeat, before a remarkable late recovery left the home side hanging on just to earn a point.
(11) In the human ventral nuclear complex there is a very clear histochemical distinction between nuclei which, on the basis of comparison with the monkey, probably form the pallidal, cerebellar and lemniscal relays to premotor, motor and somatic sensory cortex, respectively.
(12) A very high proportion of pallidal and entopeduncular neurons showed changes in firing rate during fluid injection.
(13) Statistical analysis reveals a marked difference between reconstructive surgery and simple thrombectomy, whereas fibrinolysis was found to be a useful but limited method used only in patients with pallid ischemia and in circulatory compensation.
(14) The contradiction which exists between akinesia with an abnormal activity of the medial pallidum and akinesia with bilateral pallidal lesions could only be apparent if akinesia was linked to the ineffective emission or to the interruption of messages to the thalamus.
(15) Neuroleptic administration augmented the responses to cortical stimulation in 12 of 34 pallidal neurons.
(16) A recent neuropathological study has reported decreased levels of dynorphin A immunoreactivity in striato-pallidal fibers in the brain of a patient with severe Gilles de la Tourette's syndrome (TS).
(17) This population was separate from the more numerous population of medium size globus pallidus cells projecting to the subthalamic nucleus and was also separate from the pallidal and especially peripallidal population of large cholinergic cells projecting to the cortex.
(18) We have tested the hypothesis that the basal ganglia initiate some one or several modes of movement by recording the change in discharge frequency of pallidal neurons during visually triggered step and visually paced ramp moves in relation to the visual stimulus onset, the change in the electromyograph (EMG), and the movement onset of trained rhesus monkeys.
(19) The bilateral modulatory effects of striatal stimulation may cancel out the circling behavior seen during pallidal stimulation, and cause only head turning.
(20) Oxidative phosphorylation was studied in isolated liver mitochondria from manganese-deficient mice and in those from a mutant strain, pallid.