(n.) A large vesicle or bulla, usually containing a serous fluid; a blister; a bubble, as in water, glass, etc.
Example Sentences:
(1) It has been shown by LM and transmission electron microscopy that cells with blebs are viable and capable of mitotic activity.
(2) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(3) Combined SEM and TEM examination of the endothelium of compressed segments revealed "craters" and "balloons", blebs and vacuoles, swollen mitochondria, dilated granular endoplasmic reticulum, and subendothelial edema.
(4) Ten filtrating blebs remained after a 5 months' follow-up period.
(5) These early hyperplastic lesions revealed stellate-shaped dilated bile canaliculi lined by blebs and abnormally thick elongated microvilli, a decreased number of microvilli on the sinusoidal surface, a marked increase in smooth endoplasmic reticulum, large nucleoli, and bundles of pericanalicular microfilaments.
(6) Thus, encapsulation of the filtering bleb, although requiring additional surgery in many cases, carries a favorable long-term prognosis.
(7) These mitochondria had a highly electron dense matrix and protrusions or blebs of mitochondrial outer membrane were frequently observed.
(8) An increase of cytosolic free Ca2+ is not the stimulus for bleb formation or the final common pathway leading to cell death.
(9) We recommend this skin incision for young patients with pneumothorax if the chest CT scan confirms that the bullae or blebs are localized to the apex of superior segment of the lower lobe.
(10) They induced modifications in particle distribution, a blebbing of particle-free areas and the appearance of lamellar figures on the plasma membrane of fungus cells.
(11) 2 Treatment of hepatocytes with either NABQI (0.4 mM) or paracetamol (2 mM) alone resulted in a considerable loss of cell viability, as assessed by trypan blue exclusion or leakage of lactate dehydrogenase, accompanied by an increase in the percentage of viable cells that were blebbed.
(12) Experiments where catalase was used to interrupt H2O2 exposure over a long time course revealed 15-30 minutes to be the critical period of exposure to 5 mM H2O2 necessary for a sustained increase in F actin as well as large increases in membrane blebbing and later cell death.
(13) None of the patients treated by operation (plication or resection and suture of the bleb) had a later recurrence.
(14) We have found the early placement of a therapeutic bandage contact lens permits extended administration of 5-FU during this period, minimizing discomfort and inflammation as well as enhancing bleb survival.
(15) Scanning electron microscopy showed the appearance at the culture surface of immature cells with gross surface abnormalities including large numbers of blebs, stubby microvilli and long pleomorphic microvilli.
(16) Vascular changes included perivascular deposits of proteinaceous material presumably from leakage of serum proteins, variable electron lucency of endothelial cell cytoplasm, an apparent increase in pinocytotic vesicles, rare platelet thrombosis of capillaries, and rare intravascular blebs of luminal plasma membrane.
(17) Formation of blebs was dose dependent and preceded release of LDH and trypan blue uptake.
(18) In addition, CHO cells displayed membrane bleb formations similar to those found in CHO cells after exposure to established inhibitors of protein synthesis, puromycin and anisomycin.
(19) The surfaces of the majority of these cells are covered by vesicles or blebs.
(20) In this group, 4 cases bled again because of enlargement or the development of an aneurysmal bleb.
Bled
Definition:
() imp. & p. p. of Bleed.
(imp. & p. p.) of Bleed
Example Sentences:
(1) Animals were bled 8.7-21.8% of measured blood volume [131] over 3 min, and peripheral and adrenal blood was sampled.
(2) Twelve-day-old hypertransfused neonatal rats nursed for four days by a twice-bled mother exhibited higher 48-hour RBC-59Fe incorporation than control neonates nursed by a normal mother.
(3) Animals were thyroparathyroidectomized or sham-operated and their urine was collected for 3 h. Subsequently they were anaesthetized and bled from the abdominal aorta.
(4) In transgenic mice bled to a hematocrit of 20%, a similar number and distribution of cells contained human EPO mRNA as was found with a 10% hematocrit, but the cells were less heavily labeled, indicating increased EPO production per cell at 10% hematocrit as compared with 20% hematocrit.
(5) Normal rabbits, injected with plasma from repeatedly bled, anemic, and moderately thrombocytopenic rabbits, had a 58 per cent greater maximum incorporation of 75SeM than did control animals.
(6) Mice were bled periodically and circulating idiotype levels were measured using an ELISA assay.
(7) In 21 patients (14 propranolol-, 7 placebo-treated) the hepatic venous pressure gradient decreased to less than or equal to 12 mm Hg; none of them bled from esophageal varices, and their mortality rate also decreased.
(8) Many patients on anti-inflammatory drugs bled repeatedly after apparently adequate medical or surgical treatment.
(9) Guinea pigs immunised with HSV 1 subunit vaccine were bled, and subsequently challenged intravaginally with HSV 2.
(10) After stabilization (1 hour) they were bled (40% of blood volume) over 30 minutes, then maintained in the hypotensive state (MAP = 30-40 mm Hg) for 2 hours, following which, according to randomization, they entered the control group or were resuscitated with whole blood (WB group) or with lactated Ringer's solution (LR group).
(11) Young chickens were inoculated with 5,000 PFU of eastern equine encephalitis (EEE) virus and bled at intervals thereafter for determinations of hemagglutination-inhibiting (HI), neutralizing (N), immunoglobulin M (IgM), and IgG antibodies.
(12) Histoplasmin-hypersensitive subjects (114) were bled prior to administration of the skin test, 2 days later, at the time this test was read, and 15 and 30 days after testing.
(13) In this group, 4 cases bled again because of enlargement or the development of an aneurysmal bleb.
(14) Five weeks later the mice were bled and the tetanus and diphtheria antibodies in the sera were measured.
(15) Five dairy cows were bled throughout gestation to measure serum levels of PSPB.
(16) A significant reduction of wound strength occurred in animals which had been bled for 30-60 minutes before wounding.
(17) Grossly, the majority of the tumor showed dark reddish polypoid masses with the surface bled easily.
(18) In the anaesthetized rat 0.1 N HCl was instilled into the stomach and the rat was bled to reduce the blood pressure to 30 mmHg for 20 min.
(19) We report the case of a patient with decompensated cirrhosis (Pugh class C) who bled repeatedly from gastric varices despite multiple sessions of sclerotherapy.
(20) Broiler progeny from each company were bled and serum analyzed for neutralization antibody to the S1133 reovirus.