(n.) A large vesicle or bulla, usually containing a serous fluid; a blister; a bubble, as in water, glass, etc.
Example Sentences:
(1) It has been shown by LM and transmission electron microscopy that cells with blebs are viable and capable of mitotic activity.
(2) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(3) Combined SEM and TEM examination of the endothelium of compressed segments revealed "craters" and "balloons", blebs and vacuoles, swollen mitochondria, dilated granular endoplasmic reticulum, and subendothelial edema.
(4) Ten filtrating blebs remained after a 5 months' follow-up period.
(5) These early hyperplastic lesions revealed stellate-shaped dilated bile canaliculi lined by blebs and abnormally thick elongated microvilli, a decreased number of microvilli on the sinusoidal surface, a marked increase in smooth endoplasmic reticulum, large nucleoli, and bundles of pericanalicular microfilaments.
(6) Thus, encapsulation of the filtering bleb, although requiring additional surgery in many cases, carries a favorable long-term prognosis.
(7) These mitochondria had a highly electron dense matrix and protrusions or blebs of mitochondrial outer membrane were frequently observed.
(8) An increase of cytosolic free Ca2+ is not the stimulus for bleb formation or the final common pathway leading to cell death.
(9) We recommend this skin incision for young patients with pneumothorax if the chest CT scan confirms that the bullae or blebs are localized to the apex of superior segment of the lower lobe.
(10) They induced modifications in particle distribution, a blebbing of particle-free areas and the appearance of lamellar figures on the plasma membrane of fungus cells.
(11) 2 Treatment of hepatocytes with either NABQI (0.4 mM) or paracetamol (2 mM) alone resulted in a considerable loss of cell viability, as assessed by trypan blue exclusion or leakage of lactate dehydrogenase, accompanied by an increase in the percentage of viable cells that were blebbed.
(12) Experiments where catalase was used to interrupt H2O2 exposure over a long time course revealed 15-30 minutes to be the critical period of exposure to 5 mM H2O2 necessary for a sustained increase in F actin as well as large increases in membrane blebbing and later cell death.
(13) None of the patients treated by operation (plication or resection and suture of the bleb) had a later recurrence.
(14) We have found the early placement of a therapeutic bandage contact lens permits extended administration of 5-FU during this period, minimizing discomfort and inflammation as well as enhancing bleb survival.
(15) Scanning electron microscopy showed the appearance at the culture surface of immature cells with gross surface abnormalities including large numbers of blebs, stubby microvilli and long pleomorphic microvilli.
(16) Vascular changes included perivascular deposits of proteinaceous material presumably from leakage of serum proteins, variable electron lucency of endothelial cell cytoplasm, an apparent increase in pinocytotic vesicles, rare platelet thrombosis of capillaries, and rare intravascular blebs of luminal plasma membrane.
(17) Formation of blebs was dose dependent and preceded release of LDH and trypan blue uptake.
(18) In addition, CHO cells displayed membrane bleb formations similar to those found in CHO cells after exposure to established inhibitors of protein synthesis, puromycin and anisomycin.
(19) The surfaces of the majority of these cells are covered by vesicles or blebs.
(20) In this group, 4 cases bled again because of enlargement or the development of an aneurysmal bleb.
Vesicle
Definition:
(n.) A bladderlike vessel; a membranous cavity; a cyst; a cell.
(n.) A small bladderlike body in the substance of vegetable, or upon the surface of a leaf.
(n.) A small, and more or less circular, elevation of the cuticle, containing a clear watery fluid.
(n.) A cavity or sac, especially one filled with fluid; as, the umbilical vesicle.
(n.) A small convex hollow prominence on the surface of a shell or a coral.
(n.) A small cavity, nearly spherical in form, and usually of the size of a pea or smaller, such as are common in some volcanic rocks. They are produced by the liberation of watery vapor in the molten mass.
Example Sentences:
(1) 5-HT thus appears to be the preferred substrate for uptake into platelets and for movement from cytoplasm to vesicles.
(2) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(3) Reasonably good agreement is seen between theoretical apparent rate-vesicle concentration relationships and those measured experimentally.
(4) In normal seminal vesicle, the reaction product was apparently more abundant in columnar and basal cells than in other cell types.
(5) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(6) In contrast, in primordial follicles, FSH was restricted to the germ cell but was present in both the oocyte cytoplasm and germinal vesicle.
(7) In fact, the distribution of [3H]oleate between plasma membranes and unilamellar vesicles of lipids extracted from these membranes was in favor of the lipids, indicating the absence of a detectable amount of binding to a putative fatty acid binding protein in plasma membranes.
(8) This value may be compared to a Kd of 7.3 pM obtained by the same method for the interaction of DF-VIIa with TF1-263 reconstituted into phosphatidylcholine vesicles.
(9) This is interpreted to be a consequence of the adsorption of Ca2+ on the vesicle bilayers.
(10) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(11) Although the brain AP50 is prominently phosphorylated by an endogenous protein kinase in isolated coated vesicle preparations, the neuronal AP50 was not detectably phosphorylated in intact cells as assessed by two-dimensional non-equilibrium pH gradient gel electrophoresis of labeled cells dissolved directly in SDS-containing buffers.
(12) Interaction of viable macrophages with cationic particles at 37 degrees C resulted in their "internalization" within vesicles and coated pits and a closer apposition between many segments of plasmalemma than with neutral or anionic substances.
(13) The toxins preferentially attenuate a slow phase of KCl-evoked glutamate release which may be associated with synaptic vesicle mobilization.
(14) In vitro studies indicate that dendritic cells only process proteins for a short period of time, when the rate of synthesis of MHC products and content of acidic endocytic vesicles are high.
(15) The latter findings reinforce the concept that in pathologic states associated with cerebral oedema, pinocytotic vesicles fuse to form transendothelial channels which transport plasma proteins into brain.
(16) By contrast, techniques that involved collection of OM vesicles were successful in isolating OM of B. catarrhalis.
(17) It is thus probable that secondary lysosomes become part of the macrophage vesicle.
(18) The response is dose dependent for LPA concentrations from 10(-8) to 10(-3) M. Incubation of oocytes in LPA does not induce germinal vesicle breakdown.
(19) Caffeine and 6-methylaminopurine riboside (6-N-methyladenosine differentially inhibit uptake of radioactivity from adenosine and inosine, and thus the vesicles apparently possess seperate transport systems for uptake of radioactivity from purine nucleosides and from uridine.
(20) The mean length of the seminal vesicles was 2.98 cm.