(a.) Destitute of the sense of seeing, either by natural defect or by deprivation; without sight.
(a.) Not having the faculty of discernment; destitute of intellectual light; unable or unwilling to understand or judge; as, authors are blind to their own defects.
(a.) Having such a state or condition as a thing would have to a person who is blind; not well marked or easily discernible; hidden; unseen; concealed; as, a blind path; a blind ditch.
(a.) Involved; intricate; not easily followed or traced.
(a.) Having no openings for light or passage; as, a blind wall; open only at one end; as, a blind alley; a blind gut.
(a.) Unintelligible, or not easily intelligible; as, a blind passage in a book; illegible; as, blind writing.
(a.) Abortive; failing to produce flowers or fruit; as, blind buds; blind flowers.
(v. t.) To make blind; to deprive of sight or discernment.
(v. t.) To deprive partially of vision; to make vision difficult for and painful to; to dazzle.
(v. t.) To darken; to obscure to the eye or understanding; to conceal; to deceive.
(v. t.) To cover with a thin coating of sand and fine gravel; as a road newly paved, in order that the joints between the stones may be filled.
(n.) Something to hinder sight or keep out light; a screen; a cover; esp. a hinged screen or shutter for a window; a blinder for a horse.
(n.) Something to mislead the eye or the understanding, or to conceal some covert deed or design; a subterfuge.
(n.) A blindage. See Blindage.
(n.) A halting place.
(n.) Alt. of Blinde
Example Sentences:
(1) Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial.
(2) One rare case of blind-ending branch originating in the upper third of the ureter are described.
(3) We report the results of a double-blind, placebo-controlled trial of acitretin (Soriatane) in 15 patients with moderate to severe psoriasis.
(4) In a double-blind, crossover-designed study, 9 male subjects (age range: 18-25 years) received 25 mg orally, four times per day of either S or an identically-appearing placebo (P) 2 d prior to and during HA.
(5) In a randomized double-blind study, 40 patients with coronary heart disease received intravenously either 0.025 mg nitroglycerin or placebo.
(6) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.
(7) The effect of ipratropium bromide administered at two dosage levels, 40 and 80 mug, isoproterenol, 150 mug, and placebo using a metered dose inhaler was evaluated in ten adult patients with asthma in a double-blind, crossover study.
(8) The epidemiological effectiveness of dipyridamol, an interferon-inducing agent used for the prevention of influenza and viral acute respiratory diseases, was tested in 4 epidemiological trials, 3 of them carried out as double blind trials.
(9) These lanes encourage cyclists to 'ride in the gutter' which in itself is a very dangerous riding position – especially on busy congested roads as it places the cyclist right in a motorist's blind spot.
(10) A randomised double-blind trial comparing this preparation with a so-called 'shotgun' combination containing 0.05% betamethasone 17-valerate, 0.1% gentamicin, 1.0% tolnaftate and 1.0% clioquinol in 288 patients in the Philippines resulted in a better efficacy for the diflucortolone preparation in the 80 patients with bacterially or mycotically infected skin diseases.
(11) Blinded outcomes of depression and cognition were measured initially and twice in each phase.
(12) Therefore, two-dimensional echocardiographic findings in 22 patients with perivalvular abscess found at surgery or necropsy were compared with those in 24 patients without abscess in a retrospective but blinded study.
(13) In a double-blind trial, 50 patients with subcostal incisions performed for cholecystectomy or splenectomy, received 10 ml of either 0.5% bupivacaine plain or physiological saline twice daily by wound perfusion through an indwelling drainage tube for 3 days after operation.
(14) In a double-blind, randomized, within-patient comparative study, the efficacy and tolerability of Ro 14-9706 (an arotinoid methyl sulfone) in the treatment of actinic keratoses was compared with that of tretinoin (all-trans-retinoic acid).
(15) Eighteen adult epileptic patients under CBZ therapy were evaluated in this single-blind, randomized cross-over study.
(16) A total of 17 patients suffering from musculoskeletal disease were included in a double blind study to compare the efficacy and safety of piroxicam and indomethacin.
(17) Each subject applied a vehicle cream containing 0.075% capsaicin (Axsain, GalenPharma Inc.) to a 4 cm2 area of skin on one volar forearm and vehicle alone to an identical treatment area on the other forearm, according to a double-blind procedure.
(18) A prospective, double-blind study was undertaken to assess the effectiveness of oral dexamethasone premedication in reducing a variety of side effects associated with metrizamide myelography.
(19) They then entered, on a randomized and double-blind basis, a cross-over trial of two 16-week periods, blood pressure being measured fortnightly.
(20) The design was a single-blind randomised controlled study.
Eyeless
Definition:
(a.) Without eyes; blind.
Example Sentences:
(1) This study detected deficiencies in ir-LHRH in the anterior hypothalamus of eyeless mutants.
(2) The results of protein, phospholipid and enzyme analyses were corroborated by analyses by 'genetic dissection' using an eyeless mutant line.
(3) A mutation that causes adult eyelessness (e eyeless, nonlethal, recessive) affects the earliest event in eye development (stage 1a), while a mutation that causes arrest of eye development (mi microphthalmic, lethal, recessive) acts in a later event (stage 8).
(4) These observations suggest a possible utility of the eyeless mutant axolotl for studies concerned with endocrine development in the absence of hypothalamic modulation.
(5) This arrangement was not observed in eyeless embryos.
(6) The transient expression of n alpha nAChR gene does not take place in the optic tectum of 'eyeless' embryos.
(7) On a Western blot, the antibody recognizes a 41 kDa protein that is present in the heads of yellow white flies, but not in the heads of eyeless mutant flies, eyes absent.
(8) Muscle proteins were quantified in the 1 M LiCl-soluble and distilled water-insoluble fraction of the eyeless, brainless, eviscerated and skinned carcass, as compared with a striated muscle sample from the same animal used as standard and processed in the same way as the whole carcass.
(9) The eyeless subjects showed no blanching (thus remained dark) in white cups, and they exhibited melanin spots 7 or 8 times the size of those of the other two groups.
(10) Prospective anterolateral neural fold was grafted from normal axolotls into the posterior neural fold region (statocyst area) of eyeless mutant hosts.
(11) These unilateral anteroposterior grafts stimulated bilateral eye formation in the eyeless mutant at a rate of 79%.
(12) Histological examination looking for paraldehyde-fuchsin-positive secretory neurons revealed a paired nucleus preopticus in both normals and eyeless mutants, but this region lacked the emanating paraldehyde-fuchsin-positive fiber tracts in eyeless mutants.
(13) Eyeless mutants also expressing a neural mutation were entrained by light:dark (LD) cycles, but their activity pattern in LD was changed compared to the wild-type and the eyeless mutant so.
(14) Brief heating of the oocytes and larvae of eyeless mutants during the critical periods of faceted-eye development caused an increase in the thermal sensitivity of the eye rudiments, which led to an increase in the number of one-eyed individuals among the flies that hatched.
(15) Thirty generations of selection for directional asymmetry of eye size was practiced on a stock of D. melanogaster homozygous for the mutant eyeless-recessive.
(16) Immunochemical studies were done to look at the distribution of immunoreactive luteinizing-hormone-releasing hormone (ir-LHRH) in brains of eyed and eyeless mutant axolotls of different stages.
(17) The eyeless-Dominant (eyD) mutation is a fourth chromosome insertional translocation which affects the eyes, antennae, ocelli, and sexcombs when heterozygous but is a larval-pupal lethal when homozygous.
(18) The aim of the present study was to determine the cellular site of eyeless-I (ey-I) and eyeless-2 (ey-2) gene action, causing anophthalmia or microphthalmia.
(19) The major morphological difference observed in the hypothalamus of normals compared to eyeless mutants was the reduced nature or complete lack of a preoptic recess in eyeless mutants.
(20) A model depicting 2 horizontally positioned black spots resembling facing eyes, as compared with models depicting other spot arrangements, elicits intense flight activity in young African jewel fish (Hemichromis bimaculatus) under 5 months of age and 7-month-old subadults reared apart from conspecifics with eyeless cave fish (Anoptichthys jordani).