(v. t.) The shutting up of a place by troops or ships, with the purpose of preventing ingress or egress, or the reception of supplies; as, the blockade of the ports of an enemy.
(v. t.) An obstruction to passage.
(v. t. ) To shut up, as a town or fortress, by investing it with troops or vessels or war for the purpose of preventing ingress or egress, or the introduction of supplies. See note under Blockade, n.
(n.) Hence, to shut in so as to prevent egress.
(n.) To obstruct entrance to or egress from.
Example Sentences:
(1) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(2) The blockade of H2 receptors is the primary action of these drugs; however, they possess also secondary actions which may represent untoward effects but in some cases may be actually useful (increase in prostaglandin synthesis, inhibition of LTB4 synthesis, etc.)
(3) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(4) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
(5) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(6) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(7) Propranolol, 0.85 X 10(-6) M, did not significantly depress the ouabain-enhanced rate of phase 4 depolarization but did attenuate the response to epinephrine through beta blockade.
(8) Adding prazosin (30 nM) to the perfusate completely (approximately 90%) reversed this effect (p less than 0.05), while alpha 2-adrenergic receptor blockade with yohimbine (300 nM) had no effect.
(9) In the case of unilateral blockade at the groin or pelvis, the grafts connect the lymphatics of the thigh of the affected leg with lymphatics in the contralateral healthy groin.
(10) Ten patients received intercostal nerve blockade on a total of 29 occasions in order to provide analgesia following liver transplantation and to facilitate weaning from artificial ventilation of the lungs.
(11) beta-Adrenergic blockade and Ca2+ antagonists markedly suppressed Ca2+ influx, phospholipase A2 activity, phospholipase C activity and cell death.
(12) Blockade of beta-adrenoceptors interferes with haemodynamic and metabolic adaptations and ion balance during dynamic exercise.
(13) The fractional rate constants for the accumulation or disappearance of the metabolites could be determined after pharmacological blockade of catabolic enzymes or the acid metabolite carrier.
(14) Free radical generation did not antagonise the antiarrhythmic activity of alpha adrenergic blockade.
(15) At these high doses, doxepin may cause orthostatic hypotension via a peripheral alpha-receptor blockade.
(16) In order to increase the efficiency of androgen blockade, we have used 4-MA, an inhibitor of 5 alpha-reductase, the enzyme which converts testosterone into DHT, to reduce intracellular DHT concentrations and thus facilitate the action of the antiandrogen Flutamide.
(17) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
(18) This phenomenon is similar in many respects to the antigen-induced blockade of normal antibody-secreting cells, and provides a valuable model system for analyzing the mechanisms of antigen-mediated cellular inactivation.
(19) The anesthesiologist assessed the degree of neuromuscular blockade intraoperatively prior to pharmacologic reversal either by the standard method of visually counting the number of evoked thumb twitches elicited by supramaximal train-of-four stimulation of the ulnar nerve (i.e., thumb train-of-four count), or by an alternative method such as 1) visually counting the number of evoked orbicularis oculi muscle twitches elicited by supramaximal train-of-four stimulation of the facial nerve, or 2) observing the patient for clinical evidence of partial recovery (e.g., swallowing or attempts to breathe).
(20) In conclusion, block of inhibitory innervation, and induction of electrical slow waves as a control mechanism for phasic contractile activity, seems to require blockade of an aminacrine- but not TEA-sensitive potassium conductance.
Siege
Definition:
(n.) A seat; especially, a royal seat; a throne.
(n.) Hence, place or situation; seat.
(n.) Rank; grade; station; estimation.
(n.) Passage of excrements; stool; fecal matter.
(n.) The sitting of an army around or before a fortified place for the purpose of compelling the garrison to surrender; the surrounding or investing of a place by an army, and approaching it by passages and advanced works, which cover the besiegers from the enemy's fire. See the Note under Blockade.
(n.) Hence, a continued attempt to gain possession.
(n.) The floor of a glass-furnace.
(n.) A workman's bench.
(v. t.) To besiege; to beset.
Example Sentences:
(1) Waco, Texas, will forever be known for the siege that began in February 1993 when agents of the Bureau of Alcohol, Tobacco and Firearms raided a compound owned by the Branch Davidian religious sect to investigate allegations of weapons hoarding.
(2) Monuc was not able to prevent the siege of Bukavu by rebel commanders in 2004 or to counter threats posed by the Rwandan FDLR militia or Laurent Nkunda's National Congress for the Defence of the Congolese People (CNDP) rebellion.
(3) Madaya: residents of besieged Syrian town say they are being starved to death Read more The Syrian regime and Hezbollah have put Madaya under siege for more than six months now as a response to the siege of the northern towns of Fua and Kefraya by anti-regime forces.
(4) Libraries were already under siege before the recession struck.
(5) As we settle down to chat in the deputy prime minister's ramshackle constituency base at 85 Netherfield Road, Sheffield, it is hard to dispel the impression that he's still a man under siege.
(6) Meanwhile Burnham is a blue Scouser, and nobody really hates Evertonians because they make sweets, and haven’t beaten anyone of note since Prince Rupert’s siege of 1644 .
(7) In 1993, at the Branch Davidian religious compound outside Waco, Texas, the Bureau of Alcohol, Tobacco and Firearms didn’t wait for the sect leader, David Koresh, to leave before attempting to arrest him and got into a gun battle that claimed 10 victims and led to a disastrous 51-day siege culminating in dozens more deaths.
(8) Madaya is an example of where over a million Syrians remain under siege with extremely limited medical evacuations today.” Speaking on behalf of the Syrian NGO alliance, Fadi Al-Dairi, the co-founder of Hand in Hand for Syria, told the Guardian: “We have been cooperating with OCHA, but we would add our points and OCHA Damascus would remove them.
(9) He didn't even mind the National Front turning up and sieg-heiling during gigs, which seems enormously sporting of him, given his raft of horrifying stories about experiencing racism in 60s and 70s Britain, and the scars he still bears as the result of a racially motivated 1980 knife attack.
(10) The noise was back and so was the siege, the ball thrown into the area, bodies flying.
(11) Sydney siege inquest: hostage pleaded with police to storm Lindt cafe urgently Read more They had taken cover after the final group to escape the siege had successfully fled in the early hours of 16 December 2014.
(12) The mood did not improve in 1980 when Iran's London embassy was taken over by Iraqi-backed gunmen before the siege was dramatically ended by the SAS hostage rescue.
(13) Killer Mike and Talib Kweli both appeared on news channels such as CNN and Fox to offer measured words on the situation (Killer Mike: “We have essentially gone from being communities that were policed by people from the communities to being communities that are policed by strangers, and that’s no longer a community, that’s an area that’s under siege”), while Common interrupted the MTV Video Music Awards to deliver a considered monologue on Ferguson , calling for a moment of silence “for Mike Brown and for peace in this country and in the world”.
(14) The second half came to resemble a siege, with Tottenham committing numbers forward and creating openings, and Newcastle struggling to escape their half.
(15) So they'll free a few hostages, but continue siege?
(16) Two years later, the offices of Mohamed Morsi's Muslim Brotherhood were trashed after an all-night siege , with looters seizing door-labels of prominent Brotherhood leaders as trophies.
(17) Ohler’s book may well irritate some historians; he makes flippant remarks and uses chapter titles such as “Sieg High!” and “High Hitler”.
(18) The inquest heard at times harrowing detail about how gangs of local teenagers and children, some as young as 10, had the family "under siege".
(19) An orderly process of dealing with asylum claims at the earliest point would be infinitely preferable to desperate families laying siege to central European railway stations, risking their lives clinging on to vehicles at Calais or suffocating in vehicles transporting them across borders.
(20) He says incidents like that which left Omran Daqneesh stunned and bloodied are all too common in a city under siege The pictures of the injured five-year old Omran Daqneesh have shocked the world, but doctors in Aleppo see dozens of desperate children like him every week, often with worse injuries and many entirely beyond help.