(v. t.) The shutting up of a place by troops or ships, with the purpose of preventing ingress or egress, or the reception of supplies; as, the blockade of the ports of an enemy.
(v. t.) An obstruction to passage.
(v. t. ) To shut up, as a town or fortress, by investing it with troops or vessels or war for the purpose of preventing ingress or egress, or the introduction of supplies. See note under Blockade, n.
(n.) Hence, to shut in so as to prevent egress.
(n.) To obstruct entrance to or egress from.
Example Sentences:
(1) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(2) The blockade of H2 receptors is the primary action of these drugs; however, they possess also secondary actions which may represent untoward effects but in some cases may be actually useful (increase in prostaglandin synthesis, inhibition of LTB4 synthesis, etc.)
(3) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(4) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
(5) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(6) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(7) Propranolol, 0.85 X 10(-6) M, did not significantly depress the ouabain-enhanced rate of phase 4 depolarization but did attenuate the response to epinephrine through beta blockade.
(8) Adding prazosin (30 nM) to the perfusate completely (approximately 90%) reversed this effect (p less than 0.05), while alpha 2-adrenergic receptor blockade with yohimbine (300 nM) had no effect.
(9) In the case of unilateral blockade at the groin or pelvis, the grafts connect the lymphatics of the thigh of the affected leg with lymphatics in the contralateral healthy groin.
(10) Ten patients received intercostal nerve blockade on a total of 29 occasions in order to provide analgesia following liver transplantation and to facilitate weaning from artificial ventilation of the lungs.
(11) beta-Adrenergic blockade and Ca2+ antagonists markedly suppressed Ca2+ influx, phospholipase A2 activity, phospholipase C activity and cell death.
(12) Blockade of beta-adrenoceptors interferes with haemodynamic and metabolic adaptations and ion balance during dynamic exercise.
(13) The fractional rate constants for the accumulation or disappearance of the metabolites could be determined after pharmacological blockade of catabolic enzymes or the acid metabolite carrier.
(14) Free radical generation did not antagonise the antiarrhythmic activity of alpha adrenergic blockade.
(15) At these high doses, doxepin may cause orthostatic hypotension via a peripheral alpha-receptor blockade.
(16) In order to increase the efficiency of androgen blockade, we have used 4-MA, an inhibitor of 5 alpha-reductase, the enzyme which converts testosterone into DHT, to reduce intracellular DHT concentrations and thus facilitate the action of the antiandrogen Flutamide.
(17) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
(18) This phenomenon is similar in many respects to the antigen-induced blockade of normal antibody-secreting cells, and provides a valuable model system for analyzing the mechanisms of antigen-mediated cellular inactivation.
(19) The anesthesiologist assessed the degree of neuromuscular blockade intraoperatively prior to pharmacologic reversal either by the standard method of visually counting the number of evoked thumb twitches elicited by supramaximal train-of-four stimulation of the ulnar nerve (i.e., thumb train-of-four count), or by an alternative method such as 1) visually counting the number of evoked orbicularis oculi muscle twitches elicited by supramaximal train-of-four stimulation of the facial nerve, or 2) observing the patient for clinical evidence of partial recovery (e.g., swallowing or attempts to breathe).
(20) In conclusion, block of inhibitory innervation, and induction of electrical slow waves as a control mechanism for phasic contractile activity, seems to require blockade of an aminacrine- but not TEA-sensitive potassium conductance.
Stop
Definition:
(v. t.) To close, as an aperture, by filling or by obstructing; as, to stop the ears; hence, to stanch, as a wound.
(v. t.) To obstruct; to render impassable; as, to stop a way, road, or passage.
(v. t.) To arrest the progress of; to hinder; to impede; to shut in; as, to stop a traveler; to stop the course of a stream, or a flow of blood.
(v. t.) To hinder from acting or moving; to prevent the effect or efficiency of; to cause to cease; to repress; to restrain; to suppress; to interrupt; to suspend; as, to stop the execution of a decree, the progress of vice, the approaches of old age or infirmity.
(v. t.) To regulate the sounds of, as musical strings, by pressing them against the finger board with the finger, or by shortening in any way the vibrating part.
(v. t.) To point, as a composition; to punctuate.
(v. t.) To make fast; to stopper.
(v. i.) To cease to go on; to halt, or stand still; to come to a stop.
(v. i.) To cease from any motion, or course of action.
(v. i.) To spend a short time; to reside temporarily; to stay; to tarry; as, to stop with a friend.
(n.) The act of stopping, or the state of being stopped; hindrance of progress or of action; cessation; repression; interruption; check; obstruction.
(n.) That which stops, impedes, or obstructs; as obstacle; an impediment; an obstruction.
(n.) A device, or piece, as a pin, block, pawl, etc., for arresting or limiting motion, or for determining the position to which another part shall be brought.
(n.) The closing of an aperture in the air passage, or pressure of the finger upon the string, of an instrument of music, so as to modify the tone; hence, any contrivance by which the sounds of a musical instrument are regulated.
(n.) In the organ, one of the knobs or handles at each side of the organist, by which he can draw on or shut off any register or row of pipes; the register itself; as, the vox humana stop.
(n.) A member, plain or molded, formed of a separate piece and fixed to a jamb, against which a door or window shuts. This takes the place, or answers the purpose, of a rebate. Also, a pin or block to prevent a drawer from sliding too far.
(n.) A point or mark in writing or printing intended to distinguish the sentences, parts of a sentence, or clauses; a mark of punctuation. See Punctuation.
(n.) The diaphragm used in optical instruments to cut off the marginal portions of a beam of light passing through lenses.
(n.) The depression in the face of a dog between the skull and the nasal bones. It is conspicuous in the bulldog, pug, and some other breeds.
(n.) Some part of the articulating organs, as the lips, or the tongue and palate, closed (a) so as to cut off the passage of breath or voice through the mouth and the nose (distinguished as a lip-stop, or a front-stop, etc., as in p, t, d, etc.), or (b) so as to obstruct, but not entirely cut off, the passage, as in l, n, etc.; also, any of the consonants so formed.
Example Sentences:
(1) Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remodeling.
(2) The stopped-flow technique was used to measure the rate constants for the reactions between the oxidized forms of peroxidase with luminol and the following substrates: p-iodophenol, p-bromophenol, p-clorophenol, o-iodophenol, m-iodophenol, luciferin, and 2-iodo-6-hydroxybenzothiazole.
(3) The region containing the injection stop signal (iss) has been cloned and sequenced and found to contain numerous large repeats and inverted repeats which may be part of the iss.
(4) Certainly, Saunders did not land a single blow that threatened to stop his opponent, although he took quite a few himself that threatened his titles in the final few rounds.
(5) … or a theatre and concert hall There are a total of 16 ghost stations on the Paris metro; stops that were closed or never opened.
(6) All of this in the same tones of weary nonchalance you might use to stop the dog nosing around in the bin.
(7) There are no oceans wide enough to stop us from dreaming.
(8) At the ceremony, the Taliban welcomed dialogue with Washington but said their fighters would not stop fighting.
(9) In a separate exclusive interview , Alexis Tsipras, the increasingly powerful 37-year-old Greek politician now regarded by many as holding the future of the euro in his hands, told the Guardian that he was determined "to stop the experiment" with austerity policies imposed by Germany.
(10) She stopped working only when the pain made it hard for her to get to work.
(11) A tall young Border Police officer stopped me, his rifle cradled in his arms.
(12) Crown prince Sultan Bin Abdel Aziz said yesterday that the state had "spared no effort" to avoid such disasters but added that "it cannot stop what God has preordained.
(13) Control measures were introduced rapidly, effectively stopping the epidemic.
(14) Both strong-stop DNAs are made early during in vitro reactions and decline in concentration later, consistent with postulated roles as initiators of long minus- and plus-strand DNA.
(15) Thus it appears that a portion of the adaptation to prolonged and intense endurance training that is responsible for the higher lactate threshold in the trained state persists for a long time (greater than 85 days) after training is stopped.
(16) When asked why the streets of London were not heaving with demonstrators protesting against Russia turning Aleppo into the Guernica of our times, Stop the War replied that it had no wish to add to the “jingoism” politicians were whipping up against plucky little Russia .
(17) Bacteria can stop or lessen antibodies synthesis process.
(18) Never become so enamored of your own smarts that you stop signing up for life’s hard classes.
(19) The scatter measurement was made using a standard imaging geometry with both beam stops and an additional x-ray detector placed behind the standard imaging detector.
(20) Thirteen of the dogs treated with various drug regimens lived for 90 days, after which time treatment was stopped; 10 of the dogs eventually rejected the grafts, but three had continued graft function for 6 months or longer and may be permanently tolerant.