What's the difference between blot and smudge?

Blot


Definition:

  • (v. t.) To spot, stain, or bespatter, as with ink.
  • (v. t.) To impair; to damage; to mar; to soil.
  • (v. t.) To stain with infamy; to disgrace.
  • (v. t.) To obliterate, as writing with ink; to cancel; to efface; -- generally with out; as, to blot out a word or a sentence. Often figuratively; as, to blot out offenses.
  • (v. t.) To obscure; to eclipse; to shadow.
  • (v. t.) To dry, as writing, with blotting paper.
  • (v. i.) To take a blot; as, this paper blots easily.
  • (n.) A spot or stain, as of ink on paper; a blur.
  • (n.) An obliteration of something written or printed; an erasure.
  • (n.) A spot on reputation; a stain; a disgrace; a reproach; a blemish.
  • (n.) An exposure of a single man to be taken up.
  • (n.) A single man left on a point, exposed to be taken up.
  • (n.) A weak point; a failing; an exposed point or mark.

Example Sentences:

  • (1) Western blot analysis of these mitochondria using an antibody against carnitine palmitoyltransferase II purified from beef heart demonstrates a 68-kDa protein, which under ischemic conditions apparently is decreased by 2 kDa.
  • (2) We have developed a new procedure for the rapid preparation of undegraded total RNA from cultured cells for specific quantitation by dot blotting analysis.
  • (3) Only the approximately 2.7 kb mRNA species was visualized in Northern blots of total cellular and poly(A+) RNA isolated from cardiac ventricular muscle.
  • (4) In addition to performing Northern and Western blots for tyrosinase, tyrosine hydroxylase activity (THA) and dopa oxidase activity (DOA) were measured.
  • (5) After Western blot, 2 of the 5 protein bands of swine-cag (27 and 57 kD) and 3 of the 8 protein bands of human cag (27, 32, and 57 kD) reacted with the anti-Toxoplasma antibody used in the ELISA.
  • (6) Northern blot analysis with an 18-mer radiolabelled oligonucleotide, derived from an ALP specific cDNA clone, revealed a specific mRNA of about 700-800 nucleotides in HS-24 tumor cells.
  • (7) We have examined the pattern of bFGF expression during CNS development using protein immunoblot and RNA blot analyses.
  • (8) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
  • (9) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
  • (10) cDNA isolations, RNA, and genomic DNA blots confirm the existence and expression of two genes that produce indistinguishable SOD-4 proteins.
  • (11) We studied the feasibility of using RNA and DNA from autopsies for Northern and Southern blot analysis.
  • (12) Analysis of glutamate dehydrogenase (GDH) expression by enzyme assay and immunoblots, as well as Northern and dot blots of poly (A)+ RNA, in the deletion strains indicates that there are two upstream regulatory sequences that control the level of gene expression.
  • (13) The probe encoding LHCPII hybridizes to RNAs of 9.5 and 6.6 kb on northern blots of total RNA while the 3'-end probe hybridizes only to the 6.6 kb RNA.
  • (14) Enzyme activities were measured on nitrocellulose blots by using pure enzyme preparations as well as Triton X-100-solubilized membranes.
  • (15) The results indicated a very good comparability between the dot-blot assay and IF-tests, and this dot-blot method was ascertained as a simple and useful method for the scrub typhus serodiagnosis.
  • (16) An increase in cytoplasmic PRL mRNA content was evident in all the animals treated with estrogen as revealed with cytoplasmic dot blot analysis.
  • (17) All these strains produced an enterotoxic principle, antigenically related to cholera coli family of enterotoxins, as detected by latex agglutination and immuno-dot-blot tests.
  • (18) These alterations were not dependent on the prophage integration prior to curing, and no phage DNA was detected in cured cells by blot hybridisation.
  • (19) This study shows that the sensitivity and specificity of in situ hybridisation for the detection of EBV genomes in AIDS related lymphomas approaches that of Southern blotting, even when using routinely processed archival, paraffin wax embedded material.
  • (20) Western blot analysis revealed that the effect of PMA on U-373MG cells shows specificity in that GFA protein levels decline, while those of other major cytoskeletal proteins were unaltered.

Smudge


Definition:

  • (n.) A suffocating smoke.
  • (n.) A heap of damp combustibles partially ignited and burning slowly, placed on the windward side of a house, tent, or the like, in order, by the thick smoke, to keep off mosquitoes or other insects.
  • (n.) That which is smeared upon anything; a stain; a blot; a smutch; a smear.
  • (v. t.) To stifle or smother with smoke; to smoke by means of a smudge.
  • (v. t.) To smear; to smutch; to soil; to blacken with smoke.

Example Sentences:

  • (1) The most common microscopic features included dense marrow fibrosis or "scar" formation, a sprinkling of lymphocytes in a relative absence of other inflammatory cells (especially histiocytes), and smudged, nonresorbing necrotic bone flakes.
  • (2) Peripheral blood smears from old NZB mice show an increase in circulating lymphocytes and "smudged" or ruptured cells, often seen in human CLL.
  • (3) On light microscopy, "rosette" and "smudge" cells were seen in these cases, and two patterns of virus particle distribution in infected cells were seen ultrastructurally.
  • (4) With Kitade sporting teased hair, dark, smudged makeup, ropes and an arm piercing, it's safe to assume her music will also take a turn for the darker.
  • (5) Smudging of Z-bands and diffuse dilatation of the sarcoplasmic reticulum, although occasionally diffuse and massive, were often found in otherwise normal muscle fibres and were rarely observed in severely atrophic ones.
  • (6) Renal tubular cells exhibit eccentric nuclei, with smudged chromatine, and round, refringent cytoplasmic vacuoles.
  • (7) The occurrence of smudge, as it is often called, is not very common, but is brought to the attention of most jewelers from time to time.
  • (8) Inkjet tends to be cheaper than laser, but the ink can smudge.
  • (9) There are dark smudges under her eyes, and she looks both wound up with adrenaline, and exhausted.
  • (10) Four distinct but aspecific patterns of omental pathology were identified with CT: omental caking; finely infiltrated fat with a "smudged" appearance; discrete nodules; cystic masses.
  • (11) Autopsy revealed an extensive necrotizing bronchiolitis and alveolitis with frequent "smudge cells."
  • (12) The sharp stick is now there and a little while ago I found myself high up it, wondering at a 60-mile-wide sweep in which I could see Southend-on-Sea in one direction and Ascot in the other, or, rather, smudges I was told were these pleasure grounds of poor and rich.
  • (13) It was the first of the khamseen , a dust-filled wind that sweeps in from the Sahara each spring, blurring the streets and skies into a single ochre smudge.
  • (14) A sheet of paper filled with statistics, A certificate with smudged footprints, A tiny bracelet engraved "Girl, Smith."
  • (15) We conclude that in the presence of smudge cells, leukocyte counts can be made as reliably by automated methods as by pipette and chamber technics.
  • (16) The overheating of the instruments is considered to be the main cause and the plastic materials smudges and unstable fixing of the diamond grains--as accompanying causes.
  • (17) It was histopathologically demonstrated that necrobiotic tubular cells had inclusion-bearing cells of three types: "smudge cells," Cowdry A intranuclear inclusion cells, and full-type intranuclear-containing cells.
  • (18) The smears showed cells containing nuclear inclusions with radiated strands ("rosette" cells), large homogeneously-staining nuclei ("smudge" cells) and nuclei with a "honeycomb" appearance.
  • (19) The classic appearance is that of milk of calcium, seen as linear, curvilinear, or teacup-shaped particles on horizontal-beam lateral views and as ill-defined smudges on vertical-beam craniocaudal views.
  • (20) Other presentations include milk of calcium within microcysts in a unilateral, clustered distribution; milk of calcium within macrocysts; sandlike calcifications (discrete particles rather than smudges on craniocaudal view) within cysts of various sizes; and rarely, milk of calcium within the lipid cysts of either fat necrosis or galactoceles.