(a.) Having a thick edge or point, as an instrument; dull; not sharp.
(a.) Dull in understanding; slow of discernment; stupid; -- opposed to acute.
(a.) Abrupt in address; plain; unceremonious; wanting the forms of civility; rough in manners or speech.
(a.) Hard to impress or penetrate.
(v. t.) To dull the edge or point of, by making it thicker; to make blunt.
(v. t.) To repress or weaken, as any appetite, desire, or power of the mind; to impair the force, keenness, or susceptibility, of; as, to blunt the feelings.
(n.) A fencer's foil.
(n.) A short needle with a strong point. See Needle.
(n.) Money.
Example Sentences:
(1) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
(2) The Metoclopramide-induced secretion of prolactin and aldosterone was blunted in 6 patients pretreated with 200 mg ibopamine.
(3) The computer tomographic appearances of lesions of parenchymatous organs following blunt abdominal trauma are described in 13 patients (five liver, four renal, two splenic and two pancreatic injuries).
(4) Last November he bluntly warned EU chiefs he could, if he wished, “flood Europe” with refugees.
(5) Persons with clinical abdominal findings, shock, altered sensorium, and severe chest injuries after blunt trauma should undergo the procedure.
(6) Blunt trauma to the epigastrum may result in a retroperitoneal hematoma involving the head of the pancreas and descending duodenum.
(7) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(8) Addition of Ni2+ prior to TRH blunted the component of the TRH-induced transient increase in [Ca2+]i dependent on influx of Ca2+.
(9) As previously reported, patients with affective disorders show a blunted GH response to clonidine.
(10) Blunt homicide predominated amongst White females, who were substantially older than the Coloured and African subjects.
(11) A comparison of two different restriction enzymes, which cleave the plasmid with blunt or cohesive-ended double-strand breaks, did not reveal differences in repair fidelity.
(12) The prognosis was better following blunt trauma, stretch injuries and after a spontaneous onset.
(13) Seventeen (77%) of the injuries were due to penetrating trauma and five (23%) were due to blunt trauma.
(14) The cortisol response to insulin-induced hypoglycemia and exogenous ACTH appeared to be blunted in these patients.
(15) Vagal blockade reversibly inhibited the rise of plasma PP and significantly blunted the elevation of plasma VIP.
(16) But the drugs chief, Julio Calzada, is blunt: " For 50 years, we have tried to tackle the drug problem with only one tool – penalisation – and that has failed .
(17) Average increases in resting metabolic expenditure for a group of patients following elective operation, skeletal trauma, skeletal trauma with head injury, blunt trauma, sepsis and burns were determined by indirect calorimetry and protein need by urinary nitrogen losses over extended time periods.
(18) The indication for angiography in children accident patients with blunt trauma must be set up carefully.
(19) Arterial occlusion or stenosis due to blunt trauma is rare.
(20) Also, the initial rise in V1 was blunted or blocked in all subjects.
Crude
Definition:
(superl.) In its natural state; not cooked or prepared by fire or heat; undressed; not altered, refined, or prepared for use by any artificial process; raw; as, crude flesh.
(superl.) Unripe; not mature or perfect; immature.
(superl.) Not reduced to order or form; unfinished; not arranged or prepared; ill-considered; immature.
(superl.) Undigested; unconcocted; not brought into a form to give nourishment.
(superl.) Having, or displaying, superficial and undigested knowledge; without culture or profundity; as, a crude reasoner.
(superl.) Harsh and offensive, as a color; tawdry or in bad taste, as a combination of colors, or any design or work of art.
Example Sentences:
(1) Life expectancy and the infant mortality rate are considered more useful from an operational perspective and for comparisons than is the crude death rate because they are not influenced by age structure.
(2) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(3) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(4) The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).
(5) VS had a crude topography, and receptive fields of neurons in VS were relatively large.
(6) With [125I-Tyr11]SRIF as a radiolabeled ligand, the specific ligand binding to crude membrane increased transiently in the early phase of postnatal development and then decreased.
(7) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(8) A crude extract of Brucella melitensis was obtained by sonication, centrifugation and dialysis, and analyzed by quantitative immunoelectrophoresis.
(9) These results indicate that countercurrent distribution of crude extracts in aqueous two-phase systems is a useful method to study protein-protein interaction.
(10) Optimal myocyte cultures were obtained using serial 0.2% crude trypsin digestions of hearts from 1-2-day-old rats.
(11) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(12) On subfractionation of this crude mitochondrial fraction with continuous sucrose density gradients, most of the activity of the three enzymes was found at a higher density than NAD+-isocitrate dehydrogenase and at about the same density as glutamate dehydrogenase, confirming earlier reported data for acetyl-CoA synthase.
(13) A crude membrane fraction derived from the mutant is unable to synthesize cardiolipin from phosphatidylglycerol in vitro.
(14) DNA membrane complexes from sucrose gradients, as well as the crude M-band preparation and a non-membrane-associated DNA fraction from nuclei can synthesize DNA in vitro without the addition of an external DNA template or DNA polymerase.
(15) Specificity of [125I]hCG binding to other tissues was determined by incubating crude membrane preparations of heart, skeletal muscle, liver, and kidney.
(16) Binding experiments of cyclic AMP on crude extract of dog thyroid lead to the conclusion that the maximal capacity of the specific binding site is close to the cyclic AMP content in resting thyroid cells.
(17) Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M).
(18) The extent of sialomucin adjacent to a primary colorectal cancer does provide a crude assessment of tumour invasiveness and risk of local recurrence.
(19) Effects of 4-aminomethyl-1-benzylpyrrolidin-2-one-hemifumarate (WEB 1881 FU), a novel pyrrolidinone nootropic, on acetylcholine (ACh) receptors and adrenoceptors were investigated using crude membranes of the rat brain.
(20) By immunoaffinity chromatography using the immunoadsorbent, approximately 25% of crude enterotoxin applied was recovered in the eluate.