(a.) Having a thick edge or point, as an instrument; dull; not sharp.
(a.) Dull in understanding; slow of discernment; stupid; -- opposed to acute.
(a.) Abrupt in address; plain; unceremonious; wanting the forms of civility; rough in manners or speech.
(a.) Hard to impress or penetrate.
(v. t.) To dull the edge or point of, by making it thicker; to make blunt.
(v. t.) To repress or weaken, as any appetite, desire, or power of the mind; to impair the force, keenness, or susceptibility, of; as, to blunt the feelings.
(n.) A fencer's foil.
(n.) A short needle with a strong point. See Needle.
(n.) Money.
Example Sentences:
(1) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
(2) The Metoclopramide-induced secretion of prolactin and aldosterone was blunted in 6 patients pretreated with 200 mg ibopamine.
(3) The computer tomographic appearances of lesions of parenchymatous organs following blunt abdominal trauma are described in 13 patients (five liver, four renal, two splenic and two pancreatic injuries).
(4) Last November he bluntly warned EU chiefs he could, if he wished, “flood Europe” with refugees.
(5) Persons with clinical abdominal findings, shock, altered sensorium, and severe chest injuries after blunt trauma should undergo the procedure.
(6) Blunt trauma to the epigastrum may result in a retroperitoneal hematoma involving the head of the pancreas and descending duodenum.
(7) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(8) Addition of Ni2+ prior to TRH blunted the component of the TRH-induced transient increase in [Ca2+]i dependent on influx of Ca2+.
(9) As previously reported, patients with affective disorders show a blunted GH response to clonidine.
(10) Blunt homicide predominated amongst White females, who were substantially older than the Coloured and African subjects.
(11) A comparison of two different restriction enzymes, which cleave the plasmid with blunt or cohesive-ended double-strand breaks, did not reveal differences in repair fidelity.
(12) The prognosis was better following blunt trauma, stretch injuries and after a spontaneous onset.
(13) Seventeen (77%) of the injuries were due to penetrating trauma and five (23%) were due to blunt trauma.
(14) The cortisol response to insulin-induced hypoglycemia and exogenous ACTH appeared to be blunted in these patients.
(15) Vagal blockade reversibly inhibited the rise of plasma PP and significantly blunted the elevation of plasma VIP.
(16) But the drugs chief, Julio Calzada, is blunt: " For 50 years, we have tried to tackle the drug problem with only one tool – penalisation – and that has failed .
(17) Average increases in resting metabolic expenditure for a group of patients following elective operation, skeletal trauma, skeletal trauma with head injury, blunt trauma, sepsis and burns were determined by indirect calorimetry and protein need by urinary nitrogen losses over extended time periods.
(18) The indication for angiography in children accident patients with blunt trauma must be set up carefully.
(19) Arterial occlusion or stenosis due to blunt trauma is rare.
(20) Also, the initial rise in V1 was blunted or blocked in all subjects.
Insensitive
Definition:
(a.) Not sensitive; wanting sensation, or wanting acute sensibility.
Example Sentences:
(1) In contrast, DNA polymerase alpha, the enzyme involved in chromosomal DNA replication, was relatively insensitive to CA1.
(2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(3) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(4) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(5) All three organotins inhibited cardiac Na+,K(+)-ATPase, [3H]ouabain binding, K(+)-activated p-nitrophenyl phosphatase (K(+)-PNPPase) and oligomycin-sensitive (OS) and oligomycin-insensitive (OI) Mg(2+)-ATPase in a concentration-dependent manner.
(6) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(7) However, blood with low HBeAg levels and free of detectable polymerase activity can still be infectious, since the polymerase reaction is rather insensitive compared to the radioimmunological HBeAg determination.
(8) For those synapses that were close to the soma the time constant for decay for the non-NMDA component, which was voltage insensitive, ranged from 4-8 ms. 7.
(9) A sharp decrease in oxygen uptake occurred in Neurospora crassa cells that were transferred from 30 degrees C to 45 degrees C, and the respiration that resumed later at 45 degrees C was cyanide-insensitive.
(10) The response amplitude is maximally sensitive to photons presented over durations of 30-45 min; is very insensitive to shorter light exposures; and is maintained with no evidence of adaptation over longer exposures.
(11) In contrast to the channel closing rate, the opening rate is relatively insensitive to voltage.
(12) By using pH- or Ca(2+)-sensitive dyes and recording at the ion-sensitive and -insensitive (isosbestic) wavelengths, the method can measure both cell volume changes and intracellular ionic activities.
(13) In patients with Cushing's disease or Nelson's syndrome ACTH secretion is insensitive to naloxone, presumably because of an autonomous pituitary adenoma or hypothalamic derangement.
(14) Compared to the controls, the vitamin E deprived animals were relatively insensitive to the effects of scopolamine.
(15) The chemical shifts of the C-2 proton of histidine 48 and of the C-4 proton of histidine 80, histidine residues that are close to one another and to another heterosaccharide side chain, show a similar insensitivity.
(16) Activity was insensitive to oxygen and CO if the substrates had no additional substituents on either ring or contained only electron-donating substituents.
(17) In some cases (approximately equal to 10%) the mechanism of androgen insensitivity could not be identified.
(18) We found the incorporated channels to be insensitive to calcium and octanol, and in most cases to pH in the range of 5-7, suggesting that either these agents do not interact directly with the junctional channels or that the corresponding gating regions are inactivated during the isolation and reconstitution procedures.
(19) The cattle filarial parasite Setaria digitata, a facultative anaerobe which is reported to be cyanide insensitive, lacks cytochromes and presents many unique characters.
(20) V0 estimates derived from the low load portion were positive and relatively insensitive to Ees.