(a.) Having a thick edge or point, as an instrument; dull; not sharp.
(a.) Dull in understanding; slow of discernment; stupid; -- opposed to acute.
(a.) Abrupt in address; plain; unceremonious; wanting the forms of civility; rough in manners or speech.
(a.) Hard to impress or penetrate.
(v. t.) To dull the edge or point of, by making it thicker; to make blunt.
(v. t.) To repress or weaken, as any appetite, desire, or power of the mind; to impair the force, keenness, or susceptibility, of; as, to blunt the feelings.
(n.) A fencer's foil.
(n.) A short needle with a strong point. See Needle.
(n.) Money.
Example Sentences:
(1) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
(2) The Metoclopramide-induced secretion of prolactin and aldosterone was blunted in 6 patients pretreated with 200 mg ibopamine.
(3) The computer tomographic appearances of lesions of parenchymatous organs following blunt abdominal trauma are described in 13 patients (five liver, four renal, two splenic and two pancreatic injuries).
(4) Last November he bluntly warned EU chiefs he could, if he wished, “flood Europe” with refugees.
(5) Persons with clinical abdominal findings, shock, altered sensorium, and severe chest injuries after blunt trauma should undergo the procedure.
(6) Blunt trauma to the epigastrum may result in a retroperitoneal hematoma involving the head of the pancreas and descending duodenum.
(7) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(8) Addition of Ni2+ prior to TRH blunted the component of the TRH-induced transient increase in [Ca2+]i dependent on influx of Ca2+.
(9) As previously reported, patients with affective disorders show a blunted GH response to clonidine.
(10) Blunt homicide predominated amongst White females, who were substantially older than the Coloured and African subjects.
(11) A comparison of two different restriction enzymes, which cleave the plasmid with blunt or cohesive-ended double-strand breaks, did not reveal differences in repair fidelity.
(12) The prognosis was better following blunt trauma, stretch injuries and after a spontaneous onset.
(13) Seventeen (77%) of the injuries were due to penetrating trauma and five (23%) were due to blunt trauma.
(14) The cortisol response to insulin-induced hypoglycemia and exogenous ACTH appeared to be blunted in these patients.
(15) Vagal blockade reversibly inhibited the rise of plasma PP and significantly blunted the elevation of plasma VIP.
(16) But the drugs chief, Julio Calzada, is blunt: " For 50 years, we have tried to tackle the drug problem with only one tool – penalisation – and that has failed .
(17) Average increases in resting metabolic expenditure for a group of patients following elective operation, skeletal trauma, skeletal trauma with head injury, blunt trauma, sepsis and burns were determined by indirect calorimetry and protein need by urinary nitrogen losses over extended time periods.
(18) The indication for angiography in children accident patients with blunt trauma must be set up carefully.
(19) Arterial occlusion or stenosis due to blunt trauma is rare.
(20) Also, the initial rise in V1 was blunted or blocked in all subjects.
Obtund
Definition:
(v. t.) To reduce the edge, pungency, or violent action of; to dull; to blunt; to deaden; to quell; as, to obtund the acrimony of the gall.
Example Sentences:
(1) The thigh and hip manifestations can obscure the primary intra-abdominal process either due to the obvious emphysema or to the obtunded abdominal signs secondary to associated neuropathy.
(2) Results showed the greatest inhibition of noxious stimulus perception with Innovar-Vet, lesser inhibition with ketamine-xylazine and ketamine-diazepam, and the least obtunding of nociception with pentobarbital.
(3) The use of wire stylets to facilitate passage of these tubes has increased the chances of unrecognized tracheal intubations, particularly in obtunded patients.
(4) Characteristic clinical features were present in 19 patients, including a gradual obtundation after the initial hemorrhage in 16 patients and small nonreactive pupils in nine patients (all with a Glasgow Coma Scale score of 7 or less).
(5) Kynurenic acid significantly obtunded these behavioral and physiological effects, particularly when given 60-75 min after the toxic insult.
(6) Addition of adenosine deaminase to fat cells isolated from cold-exposed rats did not normalize the lipolytic activity, suggesting that extracellular adenosine was not responsible for the obtunded lipolysis.
(7) A 59-year-old man was admitted because of frequent vomiting and obtundation in February 1982.
(8) Propofol was more effective than methohexitone at obtunding the hypertensive response to electroconvulsive therapy without causing significant hypotension.
(9) Thus, although low doses of glucocorticoids foster development of the coupling of beta-receptors to cellular transduction mechanisms, higher doses such as those used to stimulate lung function may lastingly obtund adrenergic sensitivity.
(10) Neurologic dysfunction is characterized by lethargy, obtundation, persistent vomiting, agitated delirium, and coma.
(11) The current indications for lavage are obtundation, unprotected airway, seizures, the need for urgent removal, and the tendency to form concretions.
(12) Histoplasmosis in the CNS may produce meningitis, single or multiple brain abscesses, and may present with either a clinical picture of obtundation or a deteriorating space-occupying CNS lesion.
(13) Other variables with strong predictive potential were age (P less than 0.001), the presence of multiple disease states (P less than 0.01), therapy with multiple drugs (P less than 0.01) and acute stroke or obtundation on admission (P less than 0.01).
(14) As projected by this study, scleral heterografts might well be used to obliterate bony undercuts and perhaps to obtund cystic cavities and other major bony defects.
(15) The patient became progressively more obtunded throughout the emergency department stay.
(16) The effects of 3H-epinephrine on the duration of block and on the time course of uptake and efflux of local anesthetic (14C-lidocaine hydrochloride) were determined in the infraorbital nerve of the pentobarbital-obtunded rat.
(17) Contraindications for gastric lavage are similar to those for emesis except that it may be safer to use in obtunded, comatose, or uncooperative patients.
(18) I have described a fatal case of GGS meningitis and endocarditis in a previously healthy 84-year-old who had obtundation, irritability, and cellulitis.
(19) The toxicity of dCF alone was minimal, except for one patient who became obtunded on day 5 following the first cycle of therapy.
(20) Symptoms occurred between 30-180 min with the onset of central nervous system depression, ataxia, waxing and waning obtundation, hallucinations, intermittent hysteria or hyperkinetic behavior.