(n.) An implement of steel, bone, ivory, etc., with a sharp point, for making holes by piercing; a /tiletto; an eyeleteer.
(n.) A sharp tool, like an awl, used for picking /ut letters from a column or page in making corrections.
(n.) A kind of needle with a large eye and a blunt point, for drawing tape, ribbon, etc., through a loop or a hem; a tape needle.
(n.) A kind of pin used by women to fasten the hair.
(n.) See Baudekin.
Example Sentences:
(1) A sign which appears to be almost specific for encasement, the bullet and bodkin configuration, is described here.
Hairpin
Definition:
(n.) A pin, usually forked, or of bent wire, for fastening the hair in place, -- used by women.
Example Sentences:
(1) Such conformations would account for the observed resistance of the double-hairpin structure to ligation, since the 3'OH and 5'P would no longer be collinear.
(2) Structural analysis showed that they consisted of two pairs of hairpin-palindrome type plasmids, each derived from different parts of pGKL2, respectively.
(3) It is demonstrated that this peculiar DNA fragment, under suitable conditions of concentration, salt and temperature, exclusively prefers to adopt a monomeric hairpin form with a stem of three Watson-Crick type base pairs and a loop of two residues.
(4) A short direct repeat sequence (AGGAGC), resembling the sequence shown to cause DNA polymerase alpha to pause, and sequences capable of forming hairpin loops were both present at the 5' and 3' break-points of the deletion.
(5) Each individual hairpin forms with mismatched base pairs, one containing two GT pairs and the other containing two AC pairs.
(6) The dumbbells were formed by the association of two hairpins with self-complementary dangling 5'-ends.
(7) The crystals are monoclinic, space group C2, with a = 57.18 A, b = 21.63 A, c = 36.40 A, beta = 95.22 degrees, and one hairpin molecule per asymmetric unit.
(8) (v) The bis-benzimidazole drug Hoechst-33258, which binds in the minor groove of B-DNA, exhibits very little fluorescence in the presence of the ps hairpins but a normal, enhanced emission with the aps oligonucleotides.
(9) These splinkers were designed to contain an inverted repeat sequence which forms a double-stranded hairpin structure with a known restriction site.
(10) In the preceding paper we showed that de novo initiation at the L gene is prevented by a hairpin structure that sequesters the ribosomal binding site.
(11) The model contains a high degree of secondary structure with ten stable hairpins of varying lengths and stabilities.
(12) Moreover, probably, there is a number of mRNA molecules (about 5% of the mRNA population) which are complementary in the entire length to "non-hairpin" double-stranded regions of pre-mRNA.
(13) Inhibition studies with complementary DNA oligonucleotides provide evidence for a direct role of the boxB hairpin in antitermination.
(14) The partial self-complementary 24-mer oligodeoxynucleotide d(C-G)5T4(C-G)5 forms a hairpin which can be enzymatically dimerized to a dumbbell structure.
(15) A combination of enzymatic and physical techniques has shown that the molecule contains a stable hairpin duplex of approximately 130 base pairs located at the 5' terminus of the genome.
(16) In younger teeth, the pulpal part of every giant tubule contained an afferent and an efferent blood vessel, forming a hairpin loop and being surrounded by basophil cells.
(17) In contrast, large deletions between the 44-nucleotide hairpin and the translation start site at nucleotides 60 to 62 resulted in virus that grew as well as or better than the parental virus in both chicken and mosquito cells.
(18) For instance, the substitution of one C:G with one A:T base pair in the stem helix of d(CG)7 diminishes the stability of the hairpin by 9 degrees C. It is found that the stability of the stem helix, in hairpins of defined sequence and with the same loop length, decreases in the order alternating-CG greater than homo-CG greater than AC(GT) greater than alternating-AT, i.e.
(19) The strongest facilitation is seen when the hairpin is separated from the preceding AUG codon by 14 nucleotides.
(20) Decay of the labile pufLMX segment of the operon-length transcripts begins with non-random endonucleolytic cleavage well downstream of the intercistronic hairpin structure.