What's the difference between body and pharmacodynamics?

Body


Definition:

  • (n.) The material organized substance of an animal, whether living or dead, as distinguished from the spirit, or vital principle; the physical person.
  • (n.) The trunk, or main part, of a person or animal, as distinguished from the limbs and head; the main, central, or principal part, as of a tree, army, country, etc.
  • (n.) The real, as opposed to the symbolical; the substance, as opposed to the shadow.
  • (n.) A person; a human being; -- frequently in composition; as, anybody, nobody.
  • (n.) A number of individuals spoken of collectively, usually as united by some common tie, or as organized for some purpose; a collective whole or totality; a corporation; as, a legislative body; a clerical body.
  • (n.) A number of things or particulars embodied in a system; a general collection; as, a great body of facts; a body of laws or of divinity.
  • (n.) Any mass or portion of matter; any substance distinct from others; as, a metallic body; a moving body; an aeriform body.
  • (n.) Amount; quantity; extent.
  • (n.) That part of a garment covering the body, as distinguished from the parts covering the limbs.
  • (n.) The bed or box of a vehicle, on or in which the load is placed; as, a wagon body; a cart body.
  • (n.) The shank of a type, or the depth of the shank (by which the size is indicated); as, a nonpareil face on an agate body.
  • (n.) A figure that has length, breadth, and thickness; any solid figure.
  • (n.) Consistency; thickness; substance; strength; as, this color has body; wine of a good body.
  • (v. t.) To furnish with, or as with, a body; to produce in definite shape; to embody.

Example Sentences:

  • (1) A progressively more precise approach to identifying affected individuals involves measuring body weight and height, then energy intake (or expenditure) and finally the basal metabolic rate (BMR).
  • (2) After 55 days of unrestricted food availability the body weight of the neonatally deprived rats was approximately 15% lower than that of the controls.
  • (3) Since 1987, it has become possible to obtain immature ova from the living animal and to let them mature, fertilize and develop into embryos capable of transplantation outside the body.
  • (4) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
  • (5) No associations were found between sex, body-weight, smoking habits, age, urine volume or urine pH and the O-demethylation of codeine.
  • (6) The lesion (10.6 X 9.8 mm) was a well-defined ellipsoid granuloma due to a foreign body with a central zone of necrosis surrounded entirely by a fibrous wall.
  • (7) But the sports minister has been clear that too many sports bodies are currently not delivering in bringing new people from all backgrounds to their sport.
  • (8) The 40 degrees C heating induced an increase in systolic, diastolic, average and pulse pressure at rectal temperature raised to 40 degrees C. Further growth of the body temperature was accompanied by a decrease in the above parameters.
  • (9) Plain radiographs should be the initial screening modality for a suspected foreign body.
  • (10) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
  • (11) The groups were matched with regard to sex, age and body mass index.
  • (12) The time for 90% of this change in VelCO2 to occur (T90) was measured as an index of the rate of correction of body CO2 imbalance.
  • (13) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
  • (14) There were significant differences in the body weight of control and undernourished rats in each experiment.
  • (15) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.
  • (16) The BMDs of the DM-HD group were lower in these areas and whole body than that in the non-DM,HD group.
  • (17) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
  • (18) Abruptly changing cows from one feeding system to another did not influence milk yield, milk composition, or body weight gain.
  • (19) This suggests that molars do not maintain a fixed relationship to incisors over time, and extreme care must be taken to standardize an experiment to a specific body weight when using this method.
  • (20) Our previous study demonstrated that acupuncture increased pain threshold of the body, especially in the inflammatory area.

Pharmacodynamics


Definition:

  • (n.) That branch of pharmacology which considers the mode of action, and the effects, of medicines.

Example Sentences:

  • (1) Pharmacodynamic relationships are not well established for other therapeutic effects of theophylline, such as attenuation of pharmacologically induced bronchoconstriction.
  • (2) Influences that determine a drug's effects include pharmacokinetic factors (the serum concentrations of drug as determined by the drug dose, absorption, distribution, and excretion) and pharmacodynamic factors (the intensity of drug effect).
  • (3) A sustained-release property of gelatin microcapsules of piretanide was evaluated by pharmacodynamic parameters.
  • (4) Consideration of the extravascular pharmacodynamics of azithromycin is necessary when making predictions regarding its therapeutic application.
  • (5) The differences in the effect kinetics agreed with the different pharmacodynamics, with time constants for absorption and elimination of 40 min and 240 min for meperidine, and 240 min and 840 min for imipramine.
  • (6) The differences in absorption rate between the new and the old form did not lead to relevant differences in the glucose profile and the release of insulin, so that the two forms can be regarded as being pharmacodynamically equivalent.
  • (7) The pharmacodynamics of theophylline in humans is attributed to the inhibition of phosphodiesterase activity, a concept based on in vitro studies using drug concentrations much higher than those achieved by therapeutic doses.
  • (8) Even though a dose of 100 mg DMPA every 3 months has been satisfactory for contraception, 150 mg is still recommended until further pharmacodynamic data are available.
  • (9) The pharmacokinetics and pharmacodynamics of opiates given by the subarachnoid and epidural routes are considered, in particular with respect to the comparative pharmacology of the commonly used opiates.
  • (10) TRH increases the outflow coefficient in these patients but this increase seems to be due to a pharmacodynamic action inherent in the product, and appears prior to the release of thyroid hormone.
  • (11) Circulating lipid levels, when elevated, can alter the pharmacodynamics of lipophilic drugs presumably by acting as an additional storage depot for such drugs.
  • (12) Hand angiography with examinations after cold exposure and its combination with the postreserpine pharmacodynamic studies is a useful technique in Raynaud's syndrome, both diagnostically and in predicting the outcome of longterm vasodilator therapy.
  • (13) Pharmacodynamic interactions between some NSAIDs and antihypertensive drugs, anticoagulants, sulphonylurea agents and other NSAIDs are also potentially significant in the elderly.
  • (14) The pharmacodynamic properties were found to be similar to those of Althesin, with immediate induction of anaesthesia of short duration.
  • (15) A method has been derived that allows quantitative assessment of the pharmacodynamic interaction of two compounds for which the concentration-effect relationship can be described by the Hill equation.
  • (16) A population pharmacodynamic model has been used to describe the cognitive component of the Alzheimer disease assessment scale (ADASC) using mixed effects nonlinear regression.
  • (17) The pharmacodynamic changes induced by smoking were generally most pronounced after the first cigarette following 10 hours' abstinence.
  • (18) These results indicate the close relationship between pharmacokinetics and pharmacodynamics of rhG-CSF in the rats.
  • (19) In the remaining four patients, three were diagnosed by PCG alone and one by pharmacodynamic phonocardiography using methoxamine (ME-PCG).
  • (20) The purpose of this study was to characterize the pharmacodynamics and pharmacokinetics of three concentrations of the new long-acting amide local anesthetic, ropivacaine, given epidurally in 15 physical status ASA I or II patients for elective lower-extremity orthopedic procedures using a nonrandomized open-label design.

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