(1) BOL competitively inhibited the cytotoxicity of 5,6-DHT and neither methysergide nor cyproheptadine potentiated the effect of 5,6 DHT.
(2) Every Friday night, I pass his Little Chef in Popham, Kent, and many a night we stop there, eating our way through perfect scampi and chips, spag bol of the highest order, the bill rarely sliding north of £18 for two, with drinks .
(3) The samples of c.s.f., when tested on the rat stomach fundus preparation, caused contractions which were not due, or at most to a small degree only, to 5-hydroxytryptamine, as they were resistant to BOL.
(4) It was found that (1) electrolytic destruction of medial medulla significantly diminished the depressive responses to ACh in pulmonary and carotid arteries; (2) destruction of nucleus tractus solitarius (NTS) at the level of the medullary obex did not affect the depressive responses in both arteries; obex did not affect the depressive responses in both arteries; (3) microinjection of 5-hydroxytryptamine (5-HT) blockers, cyproheptadine and 2-bromolysergic acid diethylamide (BOL), into the fourth ventricle or medial medulla could lessen the depressive responses to ACh in pulmonary and carotid arteries; (4) microinjection of naloxone in the same way could partially abolish the depressive responses.
(5) LSD and BOL were found to be equally potent in increasing the rat brain DOPA accumulation after decarboxylase inhibition.
(6) When crude BoL-IFN containing no FBS was used for purification, BoL-IFN from a selected column fraction applied to SDS-PAGE resulted in a single narrow band with an apparent molecular weight (MW) of 19,000 Da.
(7) It is proposed in addition that LSD activates and BOL blocks 5-HT receptors that control DOPA formation.
(8) Ketanserin competes with 5-HT at the 5-HT2 receptor and with BOL at the allosteric site.
(9) Even though LSD behaved as a partial agonist and BOL as a pure antagonist, both drugs blocked the effect of serotonin in an unsurmountable manner, i.e., increasing concentrations of serotonin could not overcome the blocking effect of LSD or BOL.
(10) Arop Bol speaks with affection of the other "lost boys", the comrades in adversity from southern Sudan, whom he met along the way.
(11) Radioligand binding studies showed that preincubation of membranes with either LSD or BOL reduced the density of [3H]ketanserin binding sites, suggesting that the drugs bind tightly to the 5HT2 receptor and are not displaced during the binding assay.
(12) Lysergic acid diethylamide (LSD) and its structural analogue 2-bromo-lysergic acid diethylamide (BOL) act as unsurmountable antagonists of serotonin-elicited contractions in smooth muscle preparations.
(13) The effect of apomorphine in rats given GBL was blocked by haloperidol, but not by BOL and promethazine, whereas that of LSD was inhibited by haloperidol, BOL, and promethazine.
(14) It is suggested that in the striatum LSD and BOL block autoreceptorss (presynaptic receptors) regulating the tyrosine hydroxylation.
(15) It's just like everyone else's spag bol, except it's Lucy's.
(16) Variability of the total number of type A median neurosecretory cells in the protocerebrum was studied in Micapoda elongata Linn., Elima securigera Brunn., Holochlora indica Kirby, Neoconocephalus pallidus Reclt., Latana inflata Brunn., Gryllotalpa africana Chopard, Gryllus bimaculatus De Geer, Chrotogonus oxypterus Blanchard, Aeolopus affinis Bol., Spathosternum prasiniferum Walker, Hieroglyphus furcifer Ser., Acrida exaltata Walker, Altrastomorpha cranulata Fab., Pyrgomorpha bispinosa Walker, Cyrtacanthacris ranacea Stoll and Poecilocerus pictus Fab.
(18) The abilities of D-lysergic acid diethylamide tartrate (LSD 25), methysergide maleate (UML 491) and 2-bromo-lysergic acid diethylamide (BOL 148) to antagonize the actions of these compounds were studied.2.
(19) LSD and BOL have bimodal actions: direct inhibition and agonist blockade.
(20) The son of Dinka cattle-herding parents, Arop Bol arrived in South Africa in 2002 - 15 years after he was separated from his parents during an attack on their village.