(n.) Forward to meet danger; venturesome; daring; not timorous or shrinking from risk; brave; courageous.
(n.) Exhibiting or requiring spirit and contempt of danger; planned with courage; daring; vigorous.
(n.) In a bad sense, too forward; taking undue liberties; over assuming or confident; lacking proper modesty or restraint; rude; impudent.
(n.) Somewhat overstepping usual bounds, or conventional rules, as in art, literature, etc.; taking liberties in composition or expression; as, the figures of an author are bold.
(n.) Standing prominently out to view; markedly conspicuous; striking the eye; in high relief.
(n.) Steep; abrupt; prominent.
(v. t.) To make bold or daring.
(v. i.) To be or become bold.
Example Sentences:
(1) Obamacare price hikes show that now is the time to be bold | Celine Gounder Read more No longer able to keep patients off their plans outright, insurers have resorted to other ways to discriminate and avoid paying for necessary treatments.
(2) Moments later, Strauss introduces the bold human character with an energetic, upwards melody which he titles "the climb" in the score.
(3) And that is why we have taken bold action at home – by making historic investments in renewable energy; by putting our people to work increasing efficiency in our homes and buildings; and by pursuing comprehensive legislation to transform to a clean energy economy.
(4) No doubt it was intended as a bold and graphic way of presenting the Iranian nuclear threat, but much of the initial response – on Twitter, at least – was ridicule.
(5) Noonan was also bold in his projection for Irish economic growth by 3.9% for 2015, which is higher than the original 2.7% growth predicted back in April this year.
(6) He Peirong has been at the forefront of a bold and innovative campaign by Chinese activists to free Chen and his family from their lengthy captivity.
(7) But Di Matteo has made bold selections before, not least when he asked Ramires to play on the left of midfield against Barcelona in an attempt to nullify the threat posed by the marauding Daniel Alves down the flank.
(8) But Sanders, 73, rejected the idea his appeal is limited to voters on the left, boldly predicting on Wednesday that his message would appeal to both fellow independents and Republicans.
(9) Read more The agreement earned a mixed initial reception, with the UN hailing a “bold” and “groundbreaking” outcome even as other delegates complained of “a terrible precedent” and lack of moral leadership.
(10) There is effective use of a scuba-like neoprene fabric which is slickly practical and gives a bold, shell-like silhouette to hooded coats and to sweatshirts which seems to reference the balloon and cocoon shapes that Cristobal Balenciaga invented to great acclaim in the 1950s.
(11) Previously a cover-up and reworking of a tattoo beneath, when she was performing across the UK with Girls Aloud in February , you could see the bold work in progress poking above her backless stage costumes.
(12) Blowing up the flats will on the one hand "serve as an unforgettable statement of how Glasgow is confidently embracing the future and changing for the better", while on the other it will "serve as a respectful recognition and celebration of the role the Red Road flats have played in shaping the lives of thousands of city families for whom these flats have simply been home … " According to David Zolkwer, who as the games' artistic director may have had the idea, the demolition will be "a bold and confident statement that says: 'Bring on the future'."
(13) But the equaliser was fair reward for the best move of the game and for Strachan’s own boldness in putting a player on to push back Séamus Coleman on Ireland’s right.
(14) Carney will have to defend his bold pledge to peg UK interest rates to their current record low of 7% until unemployment rate has dropped to 7%, sometime in 2016 by the Bank's reckoning.
(15) But US security experts criticised the administration for appearing to time its intervention to suit conflicting agendas of the Asean and Paris summits rather than more boldly assert the principle of freedom of navigation.
(16) Charlotte Emma Aitchison suits the bold, bratty music she makes.
(17) Advising renegotiation was "a bold recommendation" but showed the depth of backbench feeling on the issue, he added: "This is a joint committee of the Lords and the Commons, with a coalition government majority, and it's a unanimous report."
(18) The only Newcastle player that regularly took initiatives in the first half was Andros Townsend but he lacked the accuracy to make good on bold intentions.
(19) In 2007 a fresh-faced MP spent two days at the home of a Muslim family in Birmingham and then wrote boldly of how it wasn’t possible to “bully people into feeling British: we have to inspire them”; “you can’t even start to talk about a truly integrated society while people are suffering racist … abuse … on a daily basis”.
(20) After meeting the summit host, the president of the Philippines, Obama said the US and Manila had agreed on the need for “bold steps to lower tensions, including pledging to halt reclamation, new construction and militarisation of disputed islands in the South China Sea”.
Inhibit
Definition:
(v. t.) To check; to hold back; to restrain; to hinder.
(v. t.) To forbid; to prohibit; to interdict.
Example Sentences:
(1) Cellulase regulation appears to depend upon a complex relationship involving catabolite repression, inhibition, and induction.
(2) administration of the potent short-acting opioid, fentanyl, elicited inhibition of rhythmic spontaneous reflex increases in vesical pressure (VP) evoked by urinary bladder distension.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The small units described here could be inhibitory interneurons which convert the excitatory response of large units into inhibition.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(7) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(8) The fate of the inhibited fungus is the subject of this report.
(9) The present study was therefore carried out to specify further which type of adrenoceptor is involved in lithium-induced hyperglycaemia and inhibition of insulin secretion.
(10) It is suggested that the normal cyclical release of LH is inhibited in PCO disease by a negative feedback by androgens to the hypothalamus or the pituitary, and that wedge resection should be reserved for patients in whom other forms of treatment have failed.
(11) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(12) Dilutional studies comparing the mechanism of inhibition of monoamine oxidase produced by Gerovital H3 and by ipronizid demonstrated that Gerovital H3 was a reversible inhibitor of monoamine oxidase.
(13) Other research has indicated that placing gossypol in the vagina does inhibit the effect of herpes simplex virus type 2 infection, however.
(14) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(15) In Ca free-solution phenylephrine inhibited the response to CaCl2.
(16) MAF-G activity was inhibited by mitomycin C and colchicine, which inhibit DNA synthesis and mitosis, respectively, but not by 2-deoxy-D-glucose, an inhibitor of glucose metabolism.
(17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
(18) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(19) This mAb inhibited monocyte binding of both soluble FITC-labeled IgA and IgA-coated E, whereas it did not inhibit IgG binding.
(20) The inhibition was not seen in longitudinal muscle without myenteric plexus.