(n.) The hard, calcified tissue of the skeleton of vertebrate animals, consisting very largely of calcic carbonate, calcic phosphate, and gelatine; as, blood and bone.
(n.) One of the pieces or parts of an animal skeleton; as, a rib or a thigh bone; a bone of the arm or leg; also, any fragment of bony substance. (pl.) The frame or skeleton of the body.
(n.) Anything made of bone, as a bobbin for weaving bone lace.
(n.) Two or four pieces of bone held between the fingers and struck together to make a kind of music.
(n.) Dice.
(n.) Whalebone; hence, a piece of whalebone or of steel for a corset.
(n.) Fig.: The framework of anything.
(v. t.) To withdraw bones from the flesh of, as in cookery.
(v. t.) To put whalebone into; as, to bone stays.
(v. t.) To fertilize with bone.
(v. t.) To steal; to take possession of.
(v. t.) To sight along an object or set of objects, to see if it or they be level or in line, as in carpentry, masonry, and surveying.
Example Sentences:
(1) It is concluded that during exposure to simulated microgravity early signs of osteoporosis occur in the tibial spongiosa and that changes in the spongy matter of tubular bones and vertebrae are similar and systemic.
(2) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(3) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(4) It is suggested that the Japanese may have lower trabecular bone mineral density than Caucasians but may also have a lower threshold for fracture of the vertebrae.
(5) Osteoporosis is characterized by a reduction in bone density.
(6) The half-life of 45Ca in the various calcium fractions of both types of bone was 72 hours in both the control and malnourished groups except the calcium complex portion of the long bone of the control group, which was about 100 hours.
(7) We have addressed the effect of late intensification with autologous bone marrow transplantation on SCLC through a randomized clinical trial.
(8) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
(9) Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remodeling.
(10) Pokeweed mitogen-stimulated rat spleen cells were identified as a reliable source of rat burst-promoting activity (PBA), which permitted development of a reproducible assay for rat bone marrow erythroid burst-forming units (BFU-E).
(11) The fibrous matrix and cartilage formed within the nonunion site transformed to osteoid and bone with increased vascularity.
(12) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
(13) The compressive strength of bone is proportional to the square of the apparent density and to the strain rate raised to the 0.06 power.
(14) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(15) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(16) There was however no difference in the cross-sectional studies and no significant deleterious effect detected of tobacco use on forearm bone mineral content.
(17) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(18) According to the finite element analysis, the design bases of fixed restorations applied in the teeth accompanied with the absorption of the alveolar bone were preferred.
(19) At consolidation, the distraction area was composed of lamellar trabecular and partly woven bone.
(20) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
Osteomalacia
Definition:
(n.) A disease of the bones, in which they lose their earthy material, and become soft, flexible, and distorted. Also called malacia.
Example Sentences:
(1) When in addition the serum P is low (which was a feature of male patients), the danger exists for osteomalacia to develop.
(2) Osteomalacia is characterized by large osteoid seams and a preserved volume of bone trabeculae.
(3) Chronic ingestion of certain drugs can lead to osteomalacia and hypocalcemia by potentiating the metabolism of vitamin D to inactive compounds.
(4) Whereas markedly high values of 1, 25-(OH)2D in plasma were found in some cases of primary hyperparathyroidism with prominent bone resorption, relatively low values were seen in some patients with chronic renal failure, senile osteoporosis, osteomalacia and hypercalcemia due to bone metastasis.
(5) The growth plates did not increase in width despite the presence of osteomalacia and histologic evidence of extensive deposition of aluminum in bone.
(6) A follow-up biopsy examined after 12 months of therapy showed almost complete healing of osteomalacia and normal mineralization.
(7) The fractures, which appeared on roentgenograms as transverse radiolucent zones with variable callus formation, healed slowly or not at all despite treatment with calcium and vitamin D. They resembled pseudofractures (Looser's transformation zones) radiologically, but the biochemical and histologic findings were those of idiopathic osteoporosis rather than osteomalacia.
(8) A third had intestinal malabsorption, 20 had features of osteomalacia, and 87 were iron deficient.
(9) Treatment will depend on the predominant bone lesions: secondary hyperparathyroidism or osteomalacia.
(10) The various abnormalities occurred alone or in combination with one another and, to a large extent, independently of serum biochemistry.Radiological examination failed to diagnose the histological abnormality in 12 of 13 patients with osteomalacia and in 10 of 25 patients with osteitis fibrosa.
(11) The serum bio-PTH assay was useful in identifying patients with osteomalacia, low turnover bone disease, or aluminum accumulation.
(12) Thus, fractures in patients with renal failure and accumulation of aluminum may result not only from osteomalacia but also from osteopenia.
(13) Osteomalacia due to impaired liver hydroxylation of vitamin D can hardly explain the increased fracture rate and the decreased bone mass, which have been described in alcoholics.
(14) Bone biopsies (n = 3) showed a normal mineralization and the disappearance of the osteomalacia.
(15) The secondary hyperparathyroidism followed by uremic renal osteodystrophy did not result in an osteomalacia.
(16) It was shown that the serum 25-hydroxycholecalciferol level and the skeletal radiograph were the most valuable in the early detection of osteomalacia.
(17) Elevated levels persisted for six to twelve weeks after fracture, the major influence upon the level at this time being the maximum value achieved rather than the presence of osteomalacia.
(18) Pre-treatment biopsies showed signs of osteomalacia and hyperparathyroidism.
(19) We conclude that in patients with osteomalacia, a condition which is characterized by an increased osteoid accumulation due to a decreased mineralization rate, the increased level of serum osteocalcin reflects the increased osteoid synthesis but not the mineralization defect.
(20) In addition, they point out the subtle ways in which less commonly encountered metabolic bone diseases, such as osteomalacia, hyperparathyroidism, and Paget's disease, might come to the attention of the orthopedist.