(n.) A mucilaginous plant of the genus Borago (B. officinalis), which is used, esp. in France, as a demulcent and diaphoretic.
Example Sentences:
(1) The antiinflammatory effects of GLA administration observed in animal models, and the apparent clinical improvement experienced by 6 or 7 rheumatoid arthritis patients given borage seed oil in this open, uncontrolled study may be due in part to reduced generation of arachidonic acid oxygenation products.
(2) Diets were enriched (15% fat) with borage seed oil (23% GLA) or safflower oil (less than 1% GLA).
(3) Desaturase activity was influenced more by the black currant than by the borage diet, especially at 6 and 9 months of age.
(4) Low levels of the monoenes 22:1 and 24:1 found in some brands may indicate contamination of EPO with borage oil.
(5) Our results demonstrated that the animals supplemented with dietary fish oil had elevated levels of 20:5(n-3) in epidermal phospholipids and elevated epidermal levels of 15-hydroxyeicosapentaenoic acid (15-HEPE) [the 15-lipoxygenase product of 20:5(n-3)] compared with guinea pigs fed olive oil or borage oil.
(6) Weanling GPs were initially fed diets supplemented with olive oil (less than 0.1% EPA; less than 0.1% GLA) for 2 weeks, followed by a crossover by two sets of animals to diets supplemented with fish oil (19% EPA) or borage oil (25% GLA).
(7) The substrate for the delta 6-desaturase in borage was, therefore, the linoleate in the complex microsomal lipid phosphatidylcholine, rather than, as in animals, the acyl-CoA.
(8) For example, the leukotriene inhibition potentials (LIP) of both fish oil and borage oil were greatly enhanced when compared to controls.
(9) After diets, the PNE and vasoconstrictor responses to -40 mmHg LBNP, as well as the reflex vasodilation on its cessation, were significantly augmented by borage oil.
(10) The analysis revealed that five out of seven patients treated with borage oil showed a favourable effect with regard to the skin changes assessed by the ADASI-score.
(11) To test the hypothesis of a local modulatory effect of these PUFA in the epidermis, the basal diet of normal guinea pigs was supplemented with ethyl esters of either fish oil [rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] or borage oil [rich in gamma-linolenic acid (GLA)].
(12) Analysis of epidermal neutral lipids and phospholipids in borage oil-fed animals showed a marked increase in GLA and its elongase product, dihomogammalinolenic acid (DGLA).
(13) These data indicate that dietary borage oil has a blood pressure lowering effect in hypertensive and normotensive rats.
(14) To determine whether or not dietary GLA exerts any modulatory role on cutaneous eicosanoids, guinea pigs were fed either a control diet containing safflower oil (less than 0.5% GLA) or borage oil, a GLA-rich diet containing 25% GLA.
(15) To study their effects on cardiovascular reactivity to acute stress in man, 30 men were randomly assigned to one of three groups and given 28 day supplements of borage oil (containing 18:3n-6), fish oil (containing 20:5n-3), or olive oil (placebo).
(16) In a study on the effect of borage oil on atopic dermatitis, the value of this scoring system and of the statistical single-case analytic methods could be demonstrated.
(17) Similarly, animals supplemented with esters of borage oil preferentially incorporated dihomogammalinolenic acid (DGLA), the epidermal elongase product of GLA, into the epidermal phospholipids, which also was accompanied by epidermal accumulation of 15-hydroxyeicosatrienoic acid (15-HETrE).
(18) Interestingly, despite the lack of DGLA in SPH, this phospholipid exhibited a marked enrichment in nervonic acid (NA, 24:1n-9) from 16.2 to 24.7 mol% upon borage oil consumption.
(19) Mice were fed diets containing corn oil, borage oil or evening primrose oil or a mixture of borage and fish oils.
(20) Diets were supplemented with several dosages of oils containing either gamma-linolenic acid (GLA) (borage oil), eicosapentaenoic acid (EPA) (sardine oil), or a combination of the two in a dose-response protocol.
Borate
Definition:
(n.) A salt formed by the combination of boric acid with a base or positive radical.
Example Sentences:
(1) The derivatives are separated on a reversed-phase column (TSKgel ODS-120T) by gradient elution of acetonitrile in a mobile phase containing borate buffer (pH 8.5) and tetra-n-butylammonium chloride, and then determined by fluorimetry.
(2) Ultracentrifuge analyses showed similar molecular weights and laser quasi-elastic light scattering showed similar diffusions at pH 7.0 and 9.0 in borate and in the absence of borate.
(3) In both clincis phenylmercuric borate was used for desinfection of the thermometers.
(4) In borate buffer pH 8.0, with 0.15 M cyclohexanedione, the inactivation proceeds with a pseudo-first-order rate constant 0.084 hr.-1.
(5) At pH 9.0, nearly 2 mol of borate were complexed per glycotripeptide.
(6) The ability of LY 171,883 to antagonize LTC4 was eliminated in the presence of 45 mM serine borate in endothelium denuded tissues.
(7) Genomic RNA profiles were analysed by polyacrylamide gel electrophoresis (PAGE) on both 10% Laemmli and tris-borate-EDTA-(TBE)-urea gels.
(8) Noninfectious arbovirus antigens were prepared from borate-saline suspensions of infected suckling mouse brain buffered with tris(hydroxmethyl)aminomethane and treated with beta-propiolactone (BPL).
(9) Fertility (fertile eggs per 100 set) and hatchability (live chicks per 100 fertile eggs) were both nil in the borate-treated hens, compared with 57 and 95 and 59 and 100 for the control and aluminate-treated hens, respectively.
(10) (2) Borate decreases the equilibrium constant of the overall reaction in the direction of ethanol oxidation, therefore, borate enters directly into the overall reaction rather than merely decreases the effectiveness of the catalyst.
(11) The largest quantities of 125I BSA eluted with 1 M roprionic acid at pH 2.7 (86%) and 0.1 M borate buffer at pH 11.25 (80%).
(12) The nucleotide reactant NAD+ has no effect on the inactivation rate in either the presence or absence of borate.
(13) Borate also preserves white blood cells in urine and thereby marginally improved the diagnosis of pyuria.
(14) Borate bands are also observed in the spectra of other basic analytes, as well as when certain variations are made in the silver colloid preparation.
(15) glycerol or mannitol) be used to change the pH of the borate buffer for the production of greater pH gradient with a range of up to 4-5 pH units.
(16) The 0.1% dipivalyl epinephrine treatment approximated the results obtained with 1% epinephrine borate or phenylephrine 5% in reducing the intraocular pressure.
(17) In borate buffer the bulk of membranes partitioned in the poly(ethylene glycol)-rich top phase, whereas plasma membranes were pulled selectively into the dextran-rich bottom phase in the presence of ligand.
(18) The fluorophores produced in phosphate or borate buffer were the same but the fluorescence intensities were suppressed in borate buffer.
(19) S1 and G1, which comigrated in an SDS-sodium borate system, showed different mobilities upon addition of 5 M urea to the system.
(20) The bottom of the trachea was lined with mucus simulants, gels prepared from locust bean gum cross-linked with sodium borate.