(n.) A mucilaginous plant of the genus Borago (B. officinalis), which is used, esp. in France, as a demulcent and diaphoretic.
Example Sentences:
(1) The antiinflammatory effects of GLA administration observed in animal models, and the apparent clinical improvement experienced by 6 or 7 rheumatoid arthritis patients given borage seed oil in this open, uncontrolled study may be due in part to reduced generation of arachidonic acid oxygenation products.
(2) Diets were enriched (15% fat) with borage seed oil (23% GLA) or safflower oil (less than 1% GLA).
(3) Desaturase activity was influenced more by the black currant than by the borage diet, especially at 6 and 9 months of age.
(4) Low levels of the monoenes 22:1 and 24:1 found in some brands may indicate contamination of EPO with borage oil.
(5) Our results demonstrated that the animals supplemented with dietary fish oil had elevated levels of 20:5(n-3) in epidermal phospholipids and elevated epidermal levels of 15-hydroxyeicosapentaenoic acid (15-HEPE) [the 15-lipoxygenase product of 20:5(n-3)] compared with guinea pigs fed olive oil or borage oil.
(6) Weanling GPs were initially fed diets supplemented with olive oil (less than 0.1% EPA; less than 0.1% GLA) for 2 weeks, followed by a crossover by two sets of animals to diets supplemented with fish oil (19% EPA) or borage oil (25% GLA).
(7) The substrate for the delta 6-desaturase in borage was, therefore, the linoleate in the complex microsomal lipid phosphatidylcholine, rather than, as in animals, the acyl-CoA.
(8) For example, the leukotriene inhibition potentials (LIP) of both fish oil and borage oil were greatly enhanced when compared to controls.
(9) After diets, the PNE and vasoconstrictor responses to -40 mmHg LBNP, as well as the reflex vasodilation on its cessation, were significantly augmented by borage oil.
(10) The analysis revealed that five out of seven patients treated with borage oil showed a favourable effect with regard to the skin changes assessed by the ADASI-score.
(11) To test the hypothesis of a local modulatory effect of these PUFA in the epidermis, the basal diet of normal guinea pigs was supplemented with ethyl esters of either fish oil [rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] or borage oil [rich in gamma-linolenic acid (GLA)].
(12) Analysis of epidermal neutral lipids and phospholipids in borage oil-fed animals showed a marked increase in GLA and its elongase product, dihomogammalinolenic acid (DGLA).
(13) These data indicate that dietary borage oil has a blood pressure lowering effect in hypertensive and normotensive rats.
(14) To determine whether or not dietary GLA exerts any modulatory role on cutaneous eicosanoids, guinea pigs were fed either a control diet containing safflower oil (less than 0.5% GLA) or borage oil, a GLA-rich diet containing 25% GLA.
(15) To study their effects on cardiovascular reactivity to acute stress in man, 30 men were randomly assigned to one of three groups and given 28 day supplements of borage oil (containing 18:3n-6), fish oil (containing 20:5n-3), or olive oil (placebo).
(16) In a study on the effect of borage oil on atopic dermatitis, the value of this scoring system and of the statistical single-case analytic methods could be demonstrated.
(17) Similarly, animals supplemented with esters of borage oil preferentially incorporated dihomogammalinolenic acid (DGLA), the epidermal elongase product of GLA, into the epidermal phospholipids, which also was accompanied by epidermal accumulation of 15-hydroxyeicosatrienoic acid (15-HETrE).
(18) Interestingly, despite the lack of DGLA in SPH, this phospholipid exhibited a marked enrichment in nervonic acid (NA, 24:1n-9) from 16.2 to 24.7 mol% upon borage oil consumption.
(19) Mice were fed diets containing corn oil, borage oil or evening primrose oil or a mixture of borage and fish oils.
(20) Diets were supplemented with several dosages of oils containing either gamma-linolenic acid (GLA) (borage oil), eicosapentaenoic acid (EPA) (sardine oil), or a combination of the two in a dose-response protocol.
Mediterranean
Definition:
(a.) Inclosed, or nearly inclosed, with land; as, the Mediterranean Sea, between Europe and Africa.
(a.) Inland; remote from the ocean.
(a.) Of or pertaining to the Mediterranean Sea; as, Mediterranean trade; a Mediterranean voyage.
Example Sentences:
(1) Six marine bacteria which synthesize macromolecular antibiotics were isolated from neritic waters on the French Mediterranean coast, and their frequency recorded over two successive years.
(2) The authors report a resurgence of this disease during the last years, with a 5 human cases per 100,000 annual prevalence and a 6 per cent of rate death, the most active part of mediterranean area appears to be the region of Grand-Kabylie.
(3) It is now recognized that dwarfism in males is frequent around the Mediterranean, where wheat is the staple of life and has been grown for 4,000 years on the same soil, thereby resulting in the depletion of zinc.
(4) Among possible causes for the increase in deaths in the Mediterranean this year, the agency cited a worsening quality of vessels and smugglers’ tactics to avoid detection by authorities, such as sending many boats out at the same time, which makes the work of rescuers harder.
(5) The functional and phyletic significance of this material reveals a complex pattern of behavioral and phyletic diversity among large-bodied catarrhines in Europe and suggests that this diversity evolved in situ from circum-Mediterranean middle Miocene ancestors.
(6) Mediterranean countries, parts of southern Africa and South America would experience 20% to 30% less water availability.
(7) This condition is a genodermatosis, seen chiefly around the shores of the Mediterranean, characterised by early pigment disturbances which progress virtually inexorably towards a diffuse epitheliomatosis which usually results in death before the age of 20 years.
(8) A variety of sources can account for marine pollution by genotoxic, carcinogenic, and teratogenic compounds, but there is a relative paucity of analytical data concerning the Mediterranean.
(9) Vigils have been held in Cairo for the victims of EgyptAir flight 804 as a French navy ship headed to join the deep-sea search in the Mediterranean for the main wreckage and flight recorders.
(10) Novel structural changes in members of the serum amyloid A (SAA) gene family have been found in four patients of varied ethnic backgrounds with familial Mediterranean fever.
(11) Up to 100 children may have died in the weekend’s catastrophic shipwreck in the Mediterranean, a relief agency has said as prosecutors in Sicily arrested the alleged commander of the wooden fishing vessel and a member of his crew.
(12) This was equivalent to nearly nearly half the number rescued last May, a month which saw an unprecedented level of migration in the Mediterranean.
(13) Cases of cystic echinococcosis (E. granulosus) diagnosed in Central Europe are often imported from mediterranean countries.
(14) Anything that good for you might be expected to smell foul and come in a medicine bottle, but the Mediterranean diet is generally considered to be delicious, except by those who hate olive oil.
(15) Michelangelo Merisi da Caravaggio (1571-1610) died young, had a public career for only 10 years, had no workshop, bequeathed no drawings and left no pupils, and the only places he travelled to outside mainland Italy were the Mediterranean speck of Malta and, briefly, Sicily.
(16) About one-third of our postmastectomy patients are corpulent, middle-aged women with "Mediterranean" body structures.
(17) The northern Mediterranean has been Europe's soft underbelly during the crisis.
(18) They belonged to two ethnic groups--Mediterranean and Asian--and 53% were under the age of 6 years, the oldest being 20 years.
(19) Mediterranean patients (N = 16) had features intermediary between the two other groups.
(20) A C----T mutation at nucleotide 563 of G6PD Mediterranean has been identified by Vulliamy et al., and the same mutation has been found by De Vita et al.