(v. t.) To annoy; to trouble; to worry; to perplex. See Pother.
(v. i.) To feel care or anxiety; to make or take trouble; to be troublesome.
(n.) One who, or that which, bothers; state of perplexity or annoyance; embarrassment; worry; disturbance; petty trouble; as, to be in a bother.
Example Sentences:
(1) Why bother to put the investigators, prosecutors, judge, jury and me through this if one person can set justice aside, with the swipe of a pen.
(2) Unless you are part of some Unite-esque scheme to join up as part of a grand revolutionary plan, why would you bother shelling out for a membership card?
(3) Dinner is the usual “international” menu that few will bother with given the wealth of choice nearby.
(4) Despite excellent control of acute-stage emesis, some patients are still bothered by delayed emesis occurring more than 24 hours after cisplatin administration.
(5) Given this bipartisan strategy to minimise commitments, there is little wonder that voter turnout also reached a historical low, with less than two thirds bothering to vote in the east.
(6) I do think it is set fair but I am more bothered about the eurozone.
(7) These were: urinary symptoms, degree of bother due to urinary symptoms, BPH-specific interference with activities, general psychological well-being, worries and concerns, and sexual satisfaction.
(8) Interactive guide Election countdown: the key dates up to June 7 Interactive quizzes Can you be bothered?
(9) TV's Jeremy Paxman didn't even bother hiding his disdain for the introduction of weather reports to Newsnight – "It's April.
(10) And indeed both E.ON and SSE offer these for those who bother to switch,” he added.
(11) After the first couple days like everyone was like: 'Ah, I can't be bothered.
(12) Had they bothered to inquire of a veteran from the ranks, they might have heard how exasperating it is to see the dainty long-range patriots of Labour thrashing it out with the staunch gutter jingoists of the Conservative party – and barely a non-commissioned vet among them.
(13) I have been noticing, with sadness, that politicians do not even bother invoking the American Dream anymore.
(14) "No one ever bothered him at the suppers," former pastor Bob Moyer of Hartland told the paper.
(15) Refusing to play in the Seven Kingdoms league, the all black kit helps the team in matches against Wildling FC, who never bother to wear the same colours.
(16) No one else need bother to paint them as a ramshackle and rancorous rabble marooned in the past and without a plausible account of the future.
(17) With the coming of the meritocracy, the now leaderless masses were partially disfranchised; as time has gone by, more and more of them have been disengaged, and disaffected to the extent of not even bothering to vote.
(18) A cursory web search would have helped but fewer of us bother when the news is relatively inconsequential.
(19) What bothers me is that a club would contact the manager of a national team without first notifying the Federation.
(20) Arsenal responded in the only way they know, with Ramsey, Mesut Özil, Jack Wilshere and Oxlade-Chamberlain all involved in intricate passing patterns on the edge of the area, though there was no end product to bother Tim Howard apart from another long shot from Oxlade-Chamberlain that drifted wide.
Derange
Definition:
(v. t.) To put out of place, order, or rank; to disturb the proper arrangement or order of; to throw into disorder, confusion, or embarrassment; to disorder; to disarrange; as, to derange the plans of a commander, or the affairs of a nation.
(v. t.) To disturb in action or function, as a part or organ, or the whole of a machine or organism.
(v. t.) To disturb in the orderly or normal action of the intellect; to render insane.
Example Sentences:
(1) It is not known whether the deposits are primary or secondary events, but they may be of importance in initiating or maintaining derangement in heart function.
(2) All of them had fever, jaundice, abdominal pain, leucocytosis and deranged liver function while 26.6% were in shock, 13.3% in coma and 40% in azotaemia.
(3) In patients with Cushing's disease or Nelson's syndrome ACTH secretion is insensitive to naloxone, presumably because of an autonomous pituitary adenoma or hypothalamic derangement.
(4) The high ratio observed in BALF from patients with sarcoidosis and a chronic derangement of alveolar structure suggests either an increased C2 production or an alternative complement pathway (C2-independent) activation within their lungs.
(5) Progress is our understanding of the roles of vasogenic and cytotoxic brain edema in secondary brain damage can be expected from studies of the ability of biochemical factors to open the blood-brain barrier, derange the microcirculation, and cause cell swelling and necrosis.
(6) We assert that OCD and AVN are relatively common, clinically significant lesions of the mandibular condyle often associated with preexisting internal derangement of the temporomandibular joint.
(7) A hypothesis is presented as to how certain occlusal relationships and habitual patterns of jaw use may predispose an individual to TMJ internal derangements.
(8) These data suggest the feasibility of using calcium and EDTA infusions combined with an intact PTH assay to define the relationships between circulating levels of PTH-(1-84) and calcium in states of normal and deranged parathyroid physiology.
(9) Functionally, the first component reflected 55% of the reducibility property and an unimpaired oxidizability property, while the latter exhibited derangement of both aspects of cytochrome c activity.
(10) Laboratory investigations revealed hyperbilirubinemia, marked increase in serum transaminases, a variable alkaline phosphatase level and electrolytes derangement.
(11) Understanding how steroids work has led to improved comprehension of such derangements of hormonal regulation as testicular feminization.
(12) A case of a patient with a malignant schwannoma, who was originally diagnosed as having internal derangement of the temporomandibular joint (TMJ), is presented.
(13) The consequence of these derangements is often widespread plugging of small bronchi and bronchioles.
(14) The deranged adenosine metabolism and raised cAMP in the platelets of this child with severe combined immunodeficiency may explain the altered response to ADP.
(15) Surgery has been important in the treatment of internal derangement of the TMJ.
(16) Biopsies of lumbar multifidus muscles were obtained at operation on seventeen patients aged from fifteen to fifty-eight with lumbar spinal derangement, and further material was taken from the cadavers of three subjects aged from nineteen to fifty-one.
(17) Infection, compression and metabolic derangement were implicated as the most common etiologic factors.
(18) The rate of decline of creatinine clearance, the changes of the urinary protein loss, of total serum protein, of the daily insulin requirement, of the nutritional status and of some hormonal derangements were examined.
(19) Respiratory and circulatory derangements and brain damage ensue if the problem is not promptly recognized and corrected.
(20) It has been suggested that the occurrence of an intracellular Ca2+ overload may result in the development of diabetic cardiomyopathy, which is associated with depletion of high-energy phosphate stores and a derangement of ultrastructure and cardiac dysfunction.