(v. t.) To annoy; to trouble; to worry; to perplex. See Pother.
(v. i.) To feel care or anxiety; to make or take trouble; to be troublesome.
(n.) One who, or that which, bothers; state of perplexity or annoyance; embarrassment; worry; disturbance; petty trouble; as, to be in a bother.
Example Sentences:
(1) Why bother to put the investigators, prosecutors, judge, jury and me through this if one person can set justice aside, with the swipe of a pen.
(2) Unless you are part of some Unite-esque scheme to join up as part of a grand revolutionary plan, why would you bother shelling out for a membership card?
(3) Dinner is the usual “international” menu that few will bother with given the wealth of choice nearby.
(4) Despite excellent control of acute-stage emesis, some patients are still bothered by delayed emesis occurring more than 24 hours after cisplatin administration.
(5) Given this bipartisan strategy to minimise commitments, there is little wonder that voter turnout also reached a historical low, with less than two thirds bothering to vote in the east.
(6) I do think it is set fair but I am more bothered about the eurozone.
(7) These were: urinary symptoms, degree of bother due to urinary symptoms, BPH-specific interference with activities, general psychological well-being, worries and concerns, and sexual satisfaction.
(8) Interactive guide Election countdown: the key dates up to June 7 Interactive quizzes Can you be bothered?
(9) TV's Jeremy Paxman didn't even bother hiding his disdain for the introduction of weather reports to Newsnight – "It's April.
(10) And indeed both E.ON and SSE offer these for those who bother to switch,” he added.
(11) After the first couple days like everyone was like: 'Ah, I can't be bothered.
(12) Had they bothered to inquire of a veteran from the ranks, they might have heard how exasperating it is to see the dainty long-range patriots of Labour thrashing it out with the staunch gutter jingoists of the Conservative party – and barely a non-commissioned vet among them.
(13) I have been noticing, with sadness, that politicians do not even bother invoking the American Dream anymore.
(14) "No one ever bothered him at the suppers," former pastor Bob Moyer of Hartland told the paper.
(15) Refusing to play in the Seven Kingdoms league, the all black kit helps the team in matches against Wildling FC, who never bother to wear the same colours.
(16) No one else need bother to paint them as a ramshackle and rancorous rabble marooned in the past and without a plausible account of the future.
(17) With the coming of the meritocracy, the now leaderless masses were partially disfranchised; as time has gone by, more and more of them have been disengaged, and disaffected to the extent of not even bothering to vote.
(18) A cursory web search would have helped but fewer of us bother when the news is relatively inconsequential.
(19) What bothers me is that a club would contact the manager of a national team without first notifying the Federation.
(20) Arsenal responded in the only way they know, with Ramsey, Mesut Özil, Jack Wilshere and Oxlade-Chamberlain all involved in intricate passing patterns on the edge of the area, though there was no end product to bother Tim Howard apart from another long shot from Oxlade-Chamberlain that drifted wide.
Irk
Definition:
(v. t.) To weary; to give pain; to annoy; -- used only impersonally at present.
Example Sentences:
(1) When the rats were grouped into animals with mild (20%), moderate (50%), and severe (80%) reductions in maximal IRK activity, it was found that the mild and moderate defects could be reversed once the receptors were subjected to extensive autophosphorylation in vitro.
(2) We characterized the mechanism of IRK inhibition and studied whether it is the consequence of a glucose-induced stimulation of protein kinase C (PKC).
(3) 18 May 2014 New £69.4bn proposal, worth £55 a share, piles pressure on AstraZeneca's board to enter negotiations with Pfizer 19 May 2014 AstraZeneca board rejects Pfizer's final £69bn takeover bid , irking some large shareholders
(4) Reports of George’s stag do at Ristorante da Ivo near St Mark’s Square with the free £3,000 meal featuring six flavours of ice cream, including takeaway cartons, initially irked me.
(5) Joleon Lescott last weekend irked supporters by clumsily saying relegation was a “weight off the shoulders”.
(6) Wenger must be the only manager in football to be irked by reports that he will be offered a new deal.
(7) Walking by last Monday, Trump gestured towards an image of his inauguration crowd – a point that still irks him – and told reporters there would soon be an official statement about the future of his national security adviser, Michael Flynn.
(8) Blogger Yomi Adegoke said: "Thinly veiling vanity as philanthropy more than irks … the pretence these images are for anything other than an onslaught of 'natural beauty' acclamations, coupled with pats on the back for 'fighting the cause' makes the no makeup selfie mania even harder to stomach."
(9) We, therefore, conclude that glucose intolerance in aging could be attributed at least in part to acquired defects in the in vivo activation of the hepatic IRK, which results in reduced phosphorylation of its putative substrate pp180.
(10) But while agreeing that the results should not be exaggerated, D'Alimonte still thinks they indicate that the Five Star shine is wearing off among some voters - including those who were irked by the rambunctious figurehead's refusal to support a minority government led by the centre-left Democratic party (PD), thus forcing the PD to form a coalition with Berlusconi's centre-right.
(11) The corporation's power online and expanding digital TV and radio channels have irked beleaguered commercial rivals, resulting in an attack by James Murdoch, head of News Corporation in the UK.
(12) The home crowd turned their ire on the Hungarian referee Viktor Kassai – his decision to dismiss Piiroja for handball in the 76th minute particularly irked them – but they were deluding themselves if they thought he was to blame.
(13) Right now is not the time.” The midfielder refused to be drawn on suggestions that his team-mates were irked by his comments, and insisted the atmosphere among the squad in Brazil was similar to during the glorious Euro 2012 campaign.
(14) Hyperglycemia causes insulin-receptor kinase (IRK) resistance in fat cells.
(15) The comments irked the geologists' professional body, which was founded in 1807 as a dining club in a London pub.
(16) Philip Hammond appears to have irked the prime minister by making a sexist remark in cabinet, exposing the tensions at the highest level of government.
(17) Look, he’s the clear frontrunner, he’s been in six debates already, answered more questions from the media than any other candidate on the stage combined.” The Fox News press release that irked Trump and led to his withdrawal read: “We learned from a secret back channel that the Ayatollah and Putin both intend to treat Donald Trump unfairly when they meet with him if he becomes president – a nefarious source tells us that Trump has his own secret plan to replace the Cabinet with his Twitter followers to see if he should even go to those meetings.” Trump derided it as “a wise guy press release .
(18) To determine whether defects in insulin receptor kinase (IRK) activity or in the phosphorylation of its physiological substrates underlie this age-related phenomenon, young (2-3 months old) and old (24-27 months old) Wistar rats were studied.
(19) Field has already irked the medallion stallion with some low blows before the bell has rung, but it looks doubtful whether punches will be pulled for the number crunchers.
(20) Linehan, who turned 44 last week, is irked by the persistence of the idea that the sitcom that brought him and Arthur Mathews to the attention of millions has canned laughter on it.