(v. t.) To annoy; to trouble; to worry; to perplex. See Pother.
(v. i.) To feel care or anxiety; to make or take trouble; to be troublesome.
(n.) One who, or that which, bothers; state of perplexity or annoyance; embarrassment; worry; disturbance; petty trouble; as, to be in a bother.
Example Sentences:
(1) Why bother to put the investigators, prosecutors, judge, jury and me through this if one person can set justice aside, with the swipe of a pen.
(2) Unless you are part of some Unite-esque scheme to join up as part of a grand revolutionary plan, why would you bother shelling out for a membership card?
(3) Dinner is the usual “international” menu that few will bother with given the wealth of choice nearby.
(4) Despite excellent control of acute-stage emesis, some patients are still bothered by delayed emesis occurring more than 24 hours after cisplatin administration.
(5) Given this bipartisan strategy to minimise commitments, there is little wonder that voter turnout also reached a historical low, with less than two thirds bothering to vote in the east.
(6) I do think it is set fair but I am more bothered about the eurozone.
(7) These were: urinary symptoms, degree of bother due to urinary symptoms, BPH-specific interference with activities, general psychological well-being, worries and concerns, and sexual satisfaction.
(8) Interactive guide Election countdown: the key dates up to June 7 Interactive quizzes Can you be bothered?
(9) TV's Jeremy Paxman didn't even bother hiding his disdain for the introduction of weather reports to Newsnight – "It's April.
(10) And indeed both E.ON and SSE offer these for those who bother to switch,” he added.
(11) After the first couple days like everyone was like: 'Ah, I can't be bothered.
(12) Had they bothered to inquire of a veteran from the ranks, they might have heard how exasperating it is to see the dainty long-range patriots of Labour thrashing it out with the staunch gutter jingoists of the Conservative party – and barely a non-commissioned vet among them.
(13) I have been noticing, with sadness, that politicians do not even bother invoking the American Dream anymore.
(14) "No one ever bothered him at the suppers," former pastor Bob Moyer of Hartland told the paper.
(15) Refusing to play in the Seven Kingdoms league, the all black kit helps the team in matches against Wildling FC, who never bother to wear the same colours.
(16) No one else need bother to paint them as a ramshackle and rancorous rabble marooned in the past and without a plausible account of the future.
(17) With the coming of the meritocracy, the now leaderless masses were partially disfranchised; as time has gone by, more and more of them have been disengaged, and disaffected to the extent of not even bothering to vote.
(18) A cursory web search would have helped but fewer of us bother when the news is relatively inconsequential.
(19) What bothers me is that a club would contact the manager of a national team without first notifying the Federation.
(20) Arsenal responded in the only way they know, with Ramsey, Mesut Özil, Jack Wilshere and Oxlade-Chamberlain all involved in intricate passing patterns on the edge of the area, though there was no end product to bother Tim Howard apart from another long shot from Oxlade-Chamberlain that drifted wide.
Irritate
Definition:
(v. t.) To render null and void.
(v. t.) To increase the action or violence of; to heighten excitement in; to intensify; to stimulate.
(v. t.) To excite anger or displeasure in; to provoke; to tease; to exasperate; to annoy; to vex; as, the insolence of a tyrant irritates his subjects.
(v. t.) To produce irritation in; to stimulate; to cause to contract. See Irritation, n., 2.
(n.) To make morbidly excitable, or oversensitive; to fret; as, the skin is irritated by friction; to irritate a wound by a coarse bandage.
(a.) Excited; heightened.
Example Sentences:
(1) Postpartum management is directed toward decreasing vasospasm and central nervous system irritability and maintaining fluid and electrolyte balance.
(2) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(3) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(4) Inhibition of binding of [3H]TPA to the receptor preparation by tigliane and ingenane DTE correlates with irritant activity in vivo, while some daphnane and 1 alpha-alkyldaphnane DTE inhibit binding of [3H]TPA in a less pronounced manner but still are very irritant.
(5) Exposure to irritants was also more common among the asthmatics than the nonasthmatics with similar exposure to organic allergens (P = 0.004).
(6) The purpose of this study was to develop a new model for the induction of chronic irritant contact dermatitis, which would reflect well the conditions of daily practice.
(7) The drug I started taking caused an irritating, chronic cough, which disappeared when I switched to an inexpensive diuretic.
(8) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
(9) Two children required lidocaine therapy for cardiac irritability manifesting as multifocal PVCs and ventricular tachycardia.
(10) In autumn, leaf-heaps composted themselves on sunken patios, and were shovelled up by irritated owners of basement flats.
(11) The dietary fibre intake of 25 patients with the irritable bowel syndrome was assessed by dietary recall over one week for the period before onset of symptoms, at diagnosis and after six months treatment with bran and a fibre-rich diet, and compared with controls matched for age and sex.
(12) A case of epidermoid tumor of the sacral area with S3 root irritation resulting in bladder dysfunction is presented and its possible relationship to spinal puncture is discussed.
(13) The present study did not identify any baseline parameters such as initial prostate volume, peak flow rates, or obstructive or irritative symptom scores that correlated with clinical outcome.
(14) Scores on the "dependent smoking" subscale of the smoking motivation questionnaire correlated significantly with overall withdrawal severity, craving, and increased irritability.
(15) The airways can be affected by inflammation, can be targets of infection, and can respond to chemical irritants with bronchoconstrictive responses.
(16) Some pulp irritation can occur if deep restorations are not placed over a protective film.
(17) MIDAZOLAM IS SUPERIOR TO DIAZEPAM IN CERTAIN WAYS: it has a more rapid onset; produces greater anterograde amnesia, less postoperative drowsiness, less venous irritation and less likelihood of thrombophlebitis development.
(18) Primary invasive adenocarcinoma of the bladder was diagnosed in a fifty-two-year-old male with a two-month history of irritative voiding symptoms.
(19) We studied seventy patients, 23 males and 47 females with irritable bowel syndrome in adolescence aged 13-19 yrs, who visited the department of psychosomatic medicine in Takano Hospital during about six year period of April, 1986-July, 1992.
(20) The study suggested that 1) diabetes and "prediabetes" produce significant changes in levels of chondroitin 4, 6, and dermatan sulfates within alveolar bone, 2) in "prediabetic" animals, interdental bone loss occurs prior to the onset of clinical symptoms and in the absence of local irritating factors, the bone height appears to return to normal levels, and 3) there may be a correlation between alveolar bone height and relative levels of dermatan sulfate.