(n.) The external or limiting line, either real or imaginary, of any object or space; that which limits or restrains, or within which something is limited or restrained; limit; confine; extent; boundary.
(v. t.) To limit; to terminate; to fix the furthest point of extension of; -- said of natural or of moral objects; to lie along, or form, a boundary of; to inclose; to circumscribe; to restrain; to confine.
(v. t.) To name the boundaries of; as, to bound France.
(v. i.) To move with a sudden spring or leap, or with a succession of springs or leaps; as the beast bounded from his den; the herd bounded across the plain.
(v. i.) To rebound, as an elastic ball.
(v. t.) To make to bound or leap; as, to bound a horse.
(v. t.) To cause to rebound; to throw so that it will rebound; as, to bound a ball on the floor.
(n.) A leap; an elastic spring; a jump.
(n.) Rebound; as, the bound of a ball.
(n.) Spring from one foot to the other.
() imp. & p. p. of Bind.
(p. p. & a.) Restrained by a hand, rope, chain, fetters, or the like.
(p. p. & a.) Inclosed in a binding or cover; as, a bound volume.
(p. p. & a.) Under legal or moral restraint or obligation.
(p. p. & a.) Constrained or compelled; destined; certain; -- followed by the infinitive; as, he is bound to succeed; he is bound to fail.
(p. p. & a.) Resolved; as, I am bound to do it.
(p. p. & a.) Constipated; costive.
(v.) Ready or intending to go; on the way toward; going; -- with to or for, or with an adverb of motion; as, a ship is bound to Cadiz, or for Cadiz.
Example Sentences:
(1) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(2) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(3) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
(4) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
(5) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(6) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(7) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(8) Electron spin resonance studies indicate the formation of two vanadyl complexes that are 1:1 in vanadyl and deferoxamine, but have two or three bound hydroxamate groups.
(9) Treatment of the bound F1-ATPase with 4-chloro-7-nitrobenzofurazan prevented complete release of the enzyme by ATP.
(10) Only estrogenic hormones are bound with high affinity.
(11) Plasma for beta-endorphin assay was preincubated with sepharose-bound anti-beta-lipotropin to remove beta-lipotropin that cross-reacted with the beta-endorphin RIA.
(12) I think part of it is you can either go places where that's bound to happen.
(13) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(14) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(15) Immunoabsorption studies showed that these four antibodies bound to the same molecule as OKT9, an antibody to the transferrin receptor.
(16) We investigated this suppression quantitatively, using a chemical assay for cell-bound and dissolved capsular polysaccharide.
(17) Only IgG2a and IgG2b myeloma proteins bound readily to IC-21 Fc-receptors, the former in nonaggregated as well as aggregated form, the latter only as aggregated complexes.
(18) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(19) Plasmids containing the inverted repeat alone bound ER, though less efficiently than did plasmids containing the entire sequence.
(20) Inhibition of fast axonal transport by an antibody specific for kinesin provides direct evidence that kinesin is involved in the translocation of membrane-bounded organelles in axons.
Need
Definition:
(n.) A state that requires supply or relief; pressing occasion for something; necessity; urgent want.
(n.) Want of the means of subsistence; poverty; indigence; destitution.
(n.) That which is needful; anything necessary to be done; (pl.) necessary things; business.
(n.) Situation of need; peril; danger.
(n.) To be in want of; to have cause or occasion for; to lack; to require, as supply or relief.
(v. i.) To be wanted; to be necessary.
(adv.) Of necessity. See Needs.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) An effective graft-surveillance protocol needs to be applicable to all patients; practical in terms of time, effort, and cost; reliable; and able to detect, grade, and assess progression of lesions.
(3) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
(4) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(5) Paradoxically, each tax holiday increases the need for the next, because companies start holding ever greater amounts of their tax offshore in the expectation that the next Republican government will announce a new one.
(6) That means deciding what job they’d like to have and outlining the steps they’ll need to take to achieve it.
(7) The obvious need for highly effective contraception in women with existing disorders of glucose metabolism has led to a search for oral contraceptive (OC) regimens for such women that are efficient but without unacceptable metabolic side effects.
(8) More research and a national policy to provide optimal nutrition for all pregnant women, including the adolescent, are needed.
(9) "Britain needs to be in the room when the euro countries meet," he said, "so that it can influence the argument and ensure that what the 17 do will not damage the market or British interests.
(10) It is suggested that the results indicate the need for full haematological screening of all patients with recurrent aphthae.
(11) As important providers of health care education, nurses need to be fully informed of the research findings relevant to effective interventions designed to motivate health-related behavior change.
(12) Elderly women need to follow the same strategies as postmenopausal women with more emphasis on prevention of falls.
(13) The problem of treatment oneside malocclusions of adult patients needs to concern of anchorange.
(14) Since the start of this week, markets have been more cautious, with bond yields in Spain reaching their highest levels in four months on Tuesday amid concern about the scale of the austerity measures being imposed by the government and fears that the country might need a bailout.
(15) Most patients of the bopindolol-group needed 1 mg once daily as compared to those on the nifedipine who required 20 mg b.i.d.
(16) But that's just it - they need to be viable in the long term.
(17) However, further improvement of culture systems is needed for active replication of HBV in vitro.
(18) In documents due to be published by the bank, it will signal a need to shed costs from a business that employs 10,000 people as it scrambles to return to profit.
(19) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(20) Parents believed they should try to normalize their child's experiences, that interactions with health care professionals required negotiation and assertiveness, and that they needed some support person(s) outside of the family.