(1) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(2) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(3) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
(4) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
(5) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(6) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(7) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(8) Electron spin resonance studies indicate the formation of two vanadyl complexes that are 1:1 in vanadyl and deferoxamine, but have two or three bound hydroxamate groups.
(9) Treatment of the bound F1-ATPase with 4-chloro-7-nitrobenzofurazan prevented complete release of the enzyme by ATP.
(10) Only estrogenic hormones are bound with high affinity.
(11) Plasma for beta-endorphin assay was preincubated with sepharose-bound anti-beta-lipotropin to remove beta-lipotropin that cross-reacted with the beta-endorphin RIA.
(12) I think part of it is you can either go places where that's bound to happen.
(13) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(14) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(15) Immunoabsorption studies showed that these four antibodies bound to the same molecule as OKT9, an antibody to the transferrin receptor.
(16) We investigated this suppression quantitatively, using a chemical assay for cell-bound and dissolved capsular polysaccharide.
(17) Only IgG2a and IgG2b myeloma proteins bound readily to IC-21 Fc-receptors, the former in nonaggregated as well as aggregated form, the latter only as aggregated complexes.
(18) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(19) Plasmids containing the inverted repeat alone bound ER, though less efficiently than did plasmids containing the entire sequence.
(20) Inhibition of fast axonal transport by an antibody specific for kinesin provides direct evidence that kinesin is involved in the translocation of membrane-bounded organelles in axons.
Compact
Definition:
(p. p. & a) Joined or held together; leagued; confederated.
(p. p. & a) Composed or made; -- with of.
(p. p. & a) Closely or firmly united, as the particles of solid bodies; firm; close; solid; dense.
(p. p. & a) Brief; close; pithy; not diffuse; not verbose; as, a compact discourse.
(v. t.) To thrust, drive, or press closely together; to join firmly; to consolidate; to make close; -- as the parts which compose a body.
(v. t.) To unite or connect firmly, as in a system.
(n.) An agreement between parties; a covenant or contract.
Example Sentences:
(1) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(2) DNA compactization by protamines and histones HI is discussed in terms of the results obtained.
(3) At S-L clefts, paranodal-nodal regions, and Schwann cell nuclei, the axonal areas were smaller and the NF densities were higher than at compact myelinated regions.
(4) A compact attachment for microscope-type instruments is described enabling to introduce, rapidly and qualitatively, minute biological speciments into melted embedding medium and ensuring the safety of optics.
(5) Laminin was already present on the cell surface at the 2-cell stage, while nidogen was first detectable on compacted 8- to 16-cell stage morulae.
(6) Both types of molecules are compact and globular in shape and apparently contain beta-pleated sheet conformation.
(7) The tail region appeared to be cleaved off, making the head region less compact.
(8) Qualitatively the cell aspirator collected epithelial cells which were better preserved morphologically, but also a larger number of compact cell clusters.
(9) The ultrastructural study of nucleoli and ribonucleoprotein-containing structures in human seminiferous tubules revealed that the nucleoli of spermatogonia, spermatocytes and Sertoli cells exhibited a tripartite structure consisting of: a fibrillar center, a compact granular portion, and a reticular portion containing both pars fibrosa and pars granulosa.
(10) Compaction of the morula is a prerequisite for subsequent differentiation of the mouse embryo.
(11) Most double-helical segments were reactive to cobra venom ribonuclease to some degree; the exceptions were the five "long-range" helices that are probably compactly folded within the structure.
(12) During powder compaction on a Manesty Betapress, peak pressures, Pmax, are reached before the punches are vertically aligned with the centres of the upper and lower compression roll support pins.
(13) Based on these results we propose that the linearization of the DNA elution dose-response curve observed after chromatin decondensation reflects a reduction in the degree of chromatin compactness in the nuclear complexes that leads to a relatively uniform distribution of the DNA on the filter and reduces trapping of elutable material in the compact nuclear structures otherwise present.
(14) Cleavage to the compacted and cavitating stages was achieved in 78% and 69%, respectively, of human embryos cocultured in 24-48 hour human ampullary subcultures as compared to 50% and 33%, respectively, for embryos grown in culture medium alone.
(15) These observations strongly suggest that (i) GCN4 specifically recognizes the central base pair, (ii) the optimal half-site for GCN4 binding is ATGAC, not ATGAG, and (iii) GCN4 is a surprisingly flexible protein that can accommodate the insertion of a single base pair in the center of its compact binding site.
(16) In fact, the large scattering angle we chose, theta = 135 degrees, allowed us to assemble a very compact source-detector device.
(17) A monoclonal antibody to the cell adhesion molecule, E-cadherin, which mediates mouse embryo compaction, completely blocks compaction induced by these activators of PKC.
(18) At rostral levels, one third of the tracts are loosely built forming a king of curtain, while they become more compact at caudal levels.
(19) This shows that the compaction of chromatin associated with transcriptional inactivation does not require phosphorylation of H3 and suggests that the level of basal phosphorylation of H1 is not correlated with the intensity of transcription or DNA replication.
(20) After 8 days of incubation, SM subdivides into superficial (compact) and deep (disperse) sublaminae.